The objective of this study was to establish an accurate, precise, sensitive, simple, fast and reliable method for the determination of ciprofloxacin hydrochloride in pure or in pharmaceutical dosage forms using Homemade instrument fluorimeter continuous flow injection analyser with solid state laser (405 nm) as a source. The method is based upon the fluorescence fluorescein sodium salt and its quenching by ciprofloxacin hydrochloride in aqueous medium. The solutions of standard and the sample were prepared in distilled water. The calibration graph was linear in the concentration range of using (10 - 100) mMol.L-1 ciprofloxacin hydrochloride (r= 0.9891) with relative standard deviation (RSD%) for 3 mMol.L-1 ciprofloxacin HCl solution is lower than 2%(n=6). A comparison was made between the newly developed method of analysis with the quoted value using the standard addition method and no significant difference between the new developed method and the quoted value by the manufacturers companies. This indicates clearly that the new method can be successfully used for the assay of the cited day.
New Approach for Determination of Ciprofloxacin by Quenched Fluorescence of Analytically Interested Species Using Continuous Flow Injection Laser Diode Fluorimeter Analyser
Ciprofloxacin hydrochloride
homemade instrument fluorimeter continuous flow injection analyser
flow injection
fluorescein sodium salt
Publication Date
Mon Nov 01 2010
Journal Name
Al-nahrain Journal Of Science
Chemical Elements Diffusion in the Solar Interior
The standard solar model and equation of state have been used to study relative diffusion of Hydrogen and Helium in the present time for solar interior
as a function of distance and depth from the center of the star. The effects of temperature and density on diffusion velocity for these chemical elements have been explaned.
It is found that heat flow which is arising from these reactions leads to an increase in helium diffusion velocity
while the temperature and density leading to a decrease in Hydrogen diffusion velocity. This means that Hydrogen behaves inversely with that for helium does through these reactions. Accordingly
diffusion percentages for Hydrogen
Helium and other Heavy Elements could be determined for the main sequence stars and white dwarf stars.