The work involves synthesis of new quinolin-2-one Schiff bases (XIII)a,b and (XIV)a,b, pyrazoles (XI)a,b and pyrazolines (XII)a,b derivatives containing isoxazoline or pyrimidine cycle starting with chalcones. 3-Aminoacetophenone was reacted with 4-bromobenzaldehyde or 4-N,N-dimethyl aminobenzaldehyde in basic medium to give chalcones (I)a,b by Claisen-Schemidt reaction. These chalcons were reacted with hydroxylamine hydrochloride or with thiourea in basic medium to form isoxazolines (II)a,b or pyrimidine-2-thion (III)a,b ,respectively.Also the pyrimidine-2-thiones (III)a,b and isoxazolines (II)a,b reacted with 4-or 3-substituted benzaldehyde and coumarin to form Schiff bases (IV)a-f (V)a-f and quinoline derivatives (VII)a-d(VIII)a-d, respectively. On the other hand, compounds (V)b,f were reacted with ethylchloroacetate in basic medium to give ester compounds (IX)a,b .The condensation of new esters (IX)a,b with hydrazine hydrate led to produce new acid hydrazides (X)a,b.The later compound refluxing with 4-substituted benzaldehyde in dry benzene to give Schiff bases (XIII)a,band (XIV)a,b while the reaction of acid hydrazides (X)a,b with acetyl acetone or ethyl aceto acetate led to formation of pyrazole (XI)a,b , pyrazoline (XII)a,b ,respectively. The synthesized compounds were characterized by melting points, FTIR,C.H.N.analysis, Mass and 1H NMR spectroscopy(of someof them) Some of the synthesized compounds have been screened for their antibacterial activities using two types of bacteria; E. Coli and Staph. aureus. All the examined compounds did not show any biological activity towards E. Coli but compound (VII)a showed activity towards Staph. aureus.
The main purpose of this article is to study the soft LC-spaces as soft spaces in which every soft Lindelöf subset of is soft closed. Also, we study the weak forms of soft LC-spaces and we discussed their relationships with soft LC-spaces as well as among themselves.
Background: The laparoscopic cholecystectomy is the gold standard for treating the symptomatic cholelithiasis. Conversion is sometimes necessary due to finding unexpected pathology,intraoperative complications or unexpected technical errors .
Objectives: The aims of this study were to determine the complications and the predictive factors of conversion in patients undergoing laparoscopic cholecystectomy for various indications in elective and acute settings in a general hospital in order to reduce the incidence rates of both , complications and conversion of laparoscopic cholecystectomy to the open technique .
Patients and Methods: This is a prospective study includ
... Show MoreThe Yamama Formation belongs to the late Berriasian-Aptian succession, which was deposited during the Lower Cretaceous period within the main shallow marine depositional environment.
Petrographic study and microfacies analysis enabled the recognition of six main microfacies for three association facies. These are the Semi-restricted, Shallow open marine and Shoal environments. The study succession represents deposition of three third order cycles, these cycles where deposited during successive episodes of relative sea level rises and still stand.
The presence of shoal association facies (oolitic packstone microfaces) between the Sulaiy and Yamama formations refer to continue the deposition during the same stage, and may s
... Show MoreCadmium Oxide and Bi doped Cadmium Oxide thin films are prepared by using the chemical spray pyrolysis technique a glass substrate at a temperature of (400?C) with volumetric concentration (2,4)%. The thickness of all prepared films is about (400±20) nm. Transmittance and Absorbance spectra are recorded in the wave length ranged (400-800) nm. The nature of electronic transitions is determined, it is found out that these films have directly allowed transition with an optical energy gap of (2.37( eV for CdO and ) 2.59, 2.62) eV for (2% ,4%) Bi doped CdO respectively. The optical constants have been evaluated before and after doping.
Sequences spaces , m , p have called quasi-Sobolev spaces were introduced by Jawad . K. Al-Delfi in 2013 [1]. In this paper , we deal with notion of quasi-inner product space by using concept of quasi-normed space which is generalized to normed space and given a relationship between pre-Hilbert space and a quasi-inner product space with important results and examples. Completeness properties in quasi-inner product space gives us concept of quasi-Hilbert space . We show that , not all quasi-Sobolev spa
... Show MoreSimple, sensitive and accurate two methods were described for the determination of terazosin. The spectrophotometric method (A) is based on measuring the spectral absorption of the ion-pair complex formed between terazosin with eosin Y in the acetate buffer medium pH 3 at 545 nm. Method (B) is based on the quantitative quenching effect of terazosin on the native fluorescence of Eosin Y at the pH 3. The quenching of the fluorescence of Eosin Y was measured at 556 nm after excitation at 345 nm. The two methods obeyed Beer’s law over the concentration ranges of 0.1-8 and 0.05-7 µg/mL for method A and B respectively. Both methods succeeded in the determination of terazosin in its tablets
Pregnancy is a stressful condition in which many physiological and metabolic functions are altered to a considerable extent . Pregnancy is a physiological state accompanied by a high-energy demand and an increased oxygen requirement. The present study aim to study selenium ,zinc cupper in the first trimester of pregnancy. The study group comprised of Fourty five pregnant women and twenty six non pregnant women as control . The samples were taken from pregnant women who come to several heath center in Baghdad city to cheak up. Laboratory investigations including Cupper, Ceruloplasmin, Total Antioxidant (TAA), malondialdehyde (MDA), glutathione (GSH), Zinc, Uric acid, and Selenium had been measured in pregnant women and control . Th
... Show MoreThe purpose of this study was to develop poloxamer-based in-situ gel of chloramphenicol aiming to increase bioavailability and prolong corneal contact time, controlling drug release, and enhancing ocular bioavailability. The in-situ gel was prepared using different concentrations of poloxamer 407 combined with hydroxypropyl methyl cellulose (HPMC) or carbapol 940 to achieve gelation temperature about physiological temperature and improve rheological behavior and gelling properties of poloxamer gel. The prepared formulations were evaluated for their appearance, pH, and sol-gel transition temperature. The formulations F2, F3, and F5 have a gelation temperature within the accepted range 35-370C an
... Show MoreAtopic dermatitis in another word Atopic Eczema is a chronic inflammatory skin disease that effecting all ages, described by lesions of eczematous and acute itch. As the objective of this study for determine the effect of variation in TSLP, IgE, and Eosinophil levels in patients with atopic dermatitis compared with a healthy control group. The level of TSLP was almost the same between the patients and the control group, and the reason was that most of the patients were treated with anti-allergic drugs. In this study, there is a significant (P = 0.004), serum level of TSLP in atopic dermatitis patient’s pre-treatment with immunotherapy (corticosteroids and antihistamines) is compared with atopic dermatitis patients’ post-tr
... Show MoreIn this paper, we introduce new conditions to prove that the existence and boundedness of the solution by convergent sequences and convergent series. The theorem of Krasnoselskii, Lebesgue’s dominated convergence theorem and fixed point theorem are used to get some sufficient conditions for the existence of solutions. Furthermore, we get sufficient conditions to guarantee the oscillatory property for all solutions in this class of equations. An illustrative example is included as an application to the main results.