In this paper, a new modification was proposed to enhance the security level in the Blowfish algorithm by increasing the difficulty of cracking the original message which will lead to be safe against unauthorized attack. This algorithm is a symmetric variable-length key, 64-bit block cipher and it is implemented using gray scale images of different sizes. Instead of using a single key in cipher operation, another key (KEY2) of one byte length was used in the proposed algorithm which has taken place in the Feistel function in the first round both in encryption and decryption processes. In addition, the proposed modified Blowfish algorithm uses five Sboxes instead of four; the additional key (KEY2) is selected randomly from additional Sbox5, the fifth Sbox is formed in GF(28) and it is variable to increase the complexity of the proposed algorithm. The obtained results were tested using many criteria: correlation criteria, number of pixels change rate (NPCR) and mean square error (MSE). These tested factors were approved by the output results which demonstrated that the correlation of image elements in the proposed algorithm was significantly reduced during the encryption operation. Also, the algorithm is very resistant to attempts of breaking the cryptographic key since two keys were used in the encryption/ decryption operations which lead to increase the complexity factor in the proposed algorithm.
Modified Blowfish Algorithm for Image Encryption using Multi Keys based on five Sboxes
Blowfish
MSE
Encryption
Decryption
NPCR
Correlation
Gray scale images
Publication Date
Tue Mar 01 2022
Journal Name
Iraqi Journal Of Agricultural Sciences
CORRELATION OF TMPRSS2-ERG GENE FUSION STATUS WITH CLINICOPATHOLOGICAL CHARACTERISTICS IN PROSTATE CANCER OF IRAQI PATIENTS
The aim of this study was to establish the existence and interaction of TMPRSS2 – ERG gene fusion status with clinicopathological features of prostate cancer patients. This research consisted of 123 embedded formalin-fixed tissues obtained from the prostate tumor patients. The above gene fusion is detected through the technique of fluorescent in situ hybridization (FISH) by means of a triple color probe. Seven samples have not been scored due to technical difficulties and 46 patients have fusion (39.6%)
while the remaining (70) have not been seen with fusion. Of the 46 fusion-positive
17 (36%) were caused by ERG-translocation
of the other 29 (63%) were caused by the interstitial segment deletion between the two genes due to their sequential position. In order to find a substantial correlation between 116 patients (fusion took place in 46 and non-fusion in 70) with clinicopathological features
the following findings were calculated: Our findings recorded non-significant correlation at age
BMI and tumor size at which (P-value >0.05).While results showed significant association with: pathological T stage (P value = 0.011)
Gleason score (P value = 0.002)
perineural invasion (P value = 0.047) and PSA (P value = 0.033). The clinicopathological features which had a considerable correlation with fusion status are very important as they aid the doctors in prognosis and treatment of such tumor.