Rifampicin (RF) considered a hepatotoxic drug. Is one of the first line successful drugs of management of tuberculosis. To reduce injury and protect liver from adverse effect of Rifampicin, this study was designed to investigate the activity of Nigella Sativa (NS) seeds powder aqueous suspension to hepato protection against Rifampicin.
For conducting this study,24 male albino rats were divided into four groups and all treated orally as follow; group І (control), received normal saline alone; group II, received RF (50mg/kg body weight/day); group III received NS it's called normal dose, (2g/kg body weight day); group IV RF (50mg/kg body weight) + NS (2g/kg body weight).Respectively for 28 days. Blood samples obtained for estimation of liver foundation parameters and enzymes such as serum alkaline phosphate (ALP), serum glutamic pyruvic transaminase (SGPT), serum glutamic Oxaloacetic transaminase (SGOT) and serum bilirubin. After rats were scarified, liver tissue sections were prepared for histopathological examination. The results parameters in treated rats in group II showed a significant (P<0.05) increase, while group IV showed a significant (P<0.05) decrease in biochemical parameters of liver. Liver histopathological examination of animal group treated with RF showed focal necrotic area in the hepatocyte and neutrophils and mononuclear cells aggregation in thickening wall of congested blood vessels with large granulomatous lesion in liver Parenchyma.
The Histological examination of pre-treatment animal group of NS (2g/kg body weight) showed near normal liver architecture with moderate aggregation of mononuclear cell around blood vessels and moderate proliferation of kupffer cells.
Pre-treatment of NS produced significant hepatoprotection by decreasing the levels of ALP, SGOT, SGPT and bilirubin. The result indicates clearly that NS possesses hepatoprotective and activity against RF induced hepato toxicity.
Understanding energy metabolism and intracellular energy transmission requires knowledge of the function and structure of the mitochondria. Issues with mitochondrial morphology, structure, and function are the most prevalent symptoms. They can damage organs such as the heart, brain, and muscle due to a variety of factors, such as oxidative damage, incorrect metabolism of energy, or genetic conditions. The control of cell metabolism and physiology depends on functional connections between mitochondrial and biological surroundings. Therefore, it is essential to research mitochondria in situ or in vivo without isolating them from their surrounding biological environment. Finding and spotting abnormal alterations in mitochondria is the
... Show MoreFree Space Optical (FSO) technology offers highly directional, high bandwidth communication channels. This technology can provide fiber-like data rate over short distances. In order to improve security associated with data transmission in FSO networks, a secure communication method based on chaotic technique is presented. In this paper, we have turned our focus on a specific class of piece wise linear one-dimensional chaotic maps. Simulation results indicate that this approach has the advantage of possessing excellent correlation property. In this paper we examine the security vulnerabilities of single FSO links and propose a solution to this problem by implementing the chaotic signal generator “reconfigurable tent map”. As synchronizat
... Show MoreThe gypseous soil may be one of the problems that face the engineers especially when it used as a foundation for hydraulic structures, roads, and other structures. Gypseous soil is strong soil and has good properties when it is dry, but the problem arises when building hydraulic installations or heavy buildings on this soil after wetting the water to the soil by raising the water table level from any source or from rainfall which leads to dissolve the gypsum content. Cement-stabilized soil has been successfully used as a facing or lining for earth channel, highway embankments and drainage ditches to reduce the risk of erosion and collapsibility of soil. This study is deliberate the treatment of gypseous soil by using a mixture
... Show MoreIn 2010, Long and Zeng introduced a new generalization of the Bernstein polynomials that depends on a parameter and called -Bernstein polynomials. After that, in 2018, Lain and Zhou studied the uniform convergence for these -polynomials and obtained a Voronovaskaja-type asymptotic formula in ordinary approximation. This paper studies the convergence theorem and gives two Voronovaskaja-type asymptotic formulas of the sequence of -Bernstein polynomials in both ordinary and simultaneous approximations. For this purpose, we discuss the possibility of finding the recurrence relations of the -th order moment for these polynomials and evaluate the values of -Bernstein for the functions , is a non-negative integer
This paper presents the design and analysis of composite right left hand (CRLH) electromagnetic bandgap (EBG) structure. The proposed unit cell is consistent of a dielectric substrate with dimensions of 5×5×1 mm 3 made of FR4-Epoxy with εr = 4.4 underneath of a conductive patch with dimensions of 4.4×4.4mm 2 . The unit cell is structured to perform a negative permittivity (ε) and negative permeability (µ) in different bands. The proposed unit cell is developed to 5G systems in the sub-6GHz bands. In this work, a complete analysis of the unit cell in terms of Sparameters, constitutive parameters and refraction index are evaluated using HFSS simulation package based on Finite Element Method (FEM).
The urbanization and climate change phenomena are global problems whose negative effects have been exacerbated in cities, and they are a reason for the formation of global warming and urban heat islands. The research came to shed light on the urban expansion of Baghdad for four decades which extended between (1981-2021) using the ArcMap Gis10.7 technique, then evaluating the impact of this expansion on the city’s climate. The climate data were taken from Baghdad station by remote sensing technique for the same period. To clarify and analyse the relationship between the expansion and climatic data, Microsoft Excel was used. The results indicated a strong relationship between them, as urbanization rates increased, especially during the f
... Show MoreBiocompatible gold nanoparticles were successfully synthesized by hibiscus plant leaf extract as a bioreactor. The prepared nanoparticles were evaluated using UV/Vis spectroscopy, Atomic Force Microscopy (AFM), Fourier Transform Infrared Spectroscopy (FT-IR), X-ray Diffraction and Scanning Electron Microscopy (SEM) . The study also investigated the effect of the different gamma irradiation doses on the size and dispersion of the produced nanoparticles. In UV- Vis spectra, the peak of Au NPs' surface plasmon resonance (SPR) was detected as a single peak at 543 nm. The gamma irradiation induced a blue shift in the SPR peak, which indicates that it might be applied as affective factor for size control. Physical as well as chemi
... Show MoreBackground: Treatment of malocclusions using removable orthodontic appliances may prepare new stagnant areas susceptible for colonization and retention of Candida species, therefore; the aim of this study was to investigate the effect of upper removable orthodontic appliances on the mucosal Candidal count in group of apparently healthy orthodontic patients. Materials and Methods: Patients enrolled in this study were children aged 8-12 years having upper removable orthodontic appliances. Candidal counts at six mucosal sites were estimated using Imprint Culture method before, 14 and 28 days during orthodontic therapy. Results: Whole mouth and individual mucosal sites for Candidal counts increase significantly during treatment with upper remov
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