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Evaluation of some bioactive effect of phenolic compounds in Costus speciosus rhizome extract
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This work was evaluated the antioxidant, antibacterial and cytotoxic activity of Costus speciosus rhizomes methanol extract. The FLC analysis showed the presence of five compounds in the methanol extract of C. speciosus rhizomes. These compounds were Quercetin (5.2mg/ml), Rutin (6.02mg/ml), Luteolin, (18.3mg/ml),
Kaempherol, (11.34mg/ml) and Coumarin (1.41mg/ml). The maximum antioxidant activity of the extract was at concentration 1000 μg/ml with free radical scavenging activity approximately 67.5%. It was less than standard ascorbic acid 85.5% and Gallic acid 90% with significant difference (p≤0.05), with no significant difference
in comparison with standard TBA 68.5%. The IC50 of extract was 3093μg/ml, while the IC50 of ascorbic acid, Gallic acid and TBA were (277.2, 364.5 and 601.3 μg/ml) respectively. The extract revealed influential growth inhibition for all bacteria used in this experiment. The extract was moderately effective at concentration 400 μg/ml of extract with inhibitory activity 50.7 % on MCF-7 cell line and IC50 139.1 μg/ml.

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Publication Date
Fri Nov 24 2023
Journal Name
Iraqi Journal Of Science
Antimicrobial Effect of Black Grape Seed Extract
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Grape is a phenolics rich plants, Black Grape seed extract was reported to have many pharmalogically benefits including antioxidant, antimicrobial, anticancer and anti aging and anti Alzheimer's properties. Black grape seed phenols were extracted by percolation method. Results showed that the minimum inhibitory concentration of phenolic extract had no effect against K.pneuminae, However, variable inhibitory effects were developed against pathogenic P.aeruginosa , E.coli ,Bacillus ,S.aureus , E.faecalis and C.albicans. We found that black grape seed extract (Vitis vinifera) was more effective against gram positive bacteria than gram negative bacteria and its effect also against pathogenic C.albicans.

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Publication Date
Sat Dec 11 2021
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Evaluation of Synergistic Antibacterial Effect of Combined Scrophularia striata Extract and Antibiotics Against Pseudomonas aeruginosa and Methicillin -Resistant Staphylococcus aureus
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Scrophularia. striata from Scrophulariacea family has been used in Iranian folk medicine for the treatment of infectious diseases. In this study we evaluated the synergistic effect of S. striata   hydroalcoholic extract (SSE) and commercially available antibiotics against P. aeroginosa and Methicillin- resistant Staphylococcus aureus (MRSA). The resazurin-based microdilution method was used to determine the minimum inhibitory concentration (MIC) values of plan extract and standard antibiotics. The interaction between standard antibiotics and SSE was evaluated by using checkerboard method. The results of this study revealed that SSE enhance the antibacterial activity of antibiotics. The combin

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Publication Date
Thu Dec 22 2022
Journal Name
Iraqi Journal Of Biotechnology
Evaluation of Antibacterial Activity of Laurus nobilis Leaves Extract against Escherichia coli Isolates
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The aim of this study is to evaluating the antibacterial activity of Laurus nobilis leaves extract on E. coli isolates. Maceration and Soxhlet apparatus were used to prepare aqueous and methanolic extracts; total phenolic content and 2,2-diphenyl-1-picrylhydrazyl (DPPH) were conducted to determine the active compounds in the extracts. The results showed that both Laurus nobilis methanolic and aqueous extracts have a noticeable effect on scavenging free radicals. Free radical scavenging activity. The total phenolic contents were 28.60 ±0.12 and 16.58 ±0.11mg/g in 50 mg/ml, in methanolic and aqueous extracts respectively. The antibacterial activity of Laurus nobilis leaves extracts showed that the methanolic extract was more effective than

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Publication Date
Wed Apr 26 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Evaluation of the Effect of Some Plant Extracts on Mice Mammary Adenocarcinoma (AMN3).
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   The cytotoxic effect of different concentrations of Crude extracts of  Solanum melongena  , Curcuma longa and  Daucus carota  on  mice mammary adenocarcinoma cell line was  studied . The concentrations  used were 62.5 125 , 250, 500 Microgram/militer for 24,48 and 72 hour . These exracts were prepared by  using alcoholic and  hot water methods . The preliminary chemical tests revealed acidic pH of all  extracts. The results showed  a clear  toxic effect of all extracts in a time and dose –dependent manner . The Curcuma longa  had the highest effect on adenocarcinoma 94.61% , followed by Solanum melonga( 93.20%)   and the lowest effect was by Da

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Publication Date
Sat Jul 01 2023
Journal Name
The Egyptian Journal Of Hospital Medicine
Evaluation of the Antibiofilm Activity of Laurus nobilis Leaves Extract and Assessment of Its Effect on fimA and papC genes in Escherichia coli isolates
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Background: The beneficial gut bacterium E. coli can cause blood poisoning, diarrhoea, and other gastrointestinal and systemic disorders. Objective: This study amid to examines the antibiofilm activity of Laurus nobilis leaves extract on E. coli isolates and compares pre- and post-treatment gene expression of fimA and papC genes. Subjects and Methods: Ten isolates of E. coli were obtained from the Genetic Engineering and Biotechnology Institute, University of Baghdad, which was previously collected from Baghdad city hospitals and diagnosed by chemical tests, the diagnosis was confirmed using VITEK-2 System. The preparation of the aqueous and methanolic Laurus nobilis leaves extracts was done by using the maceration method and Soxhlet appara

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Publication Date
Wed Jan 01 2020
Journal Name
Annals Of Tropical Medicine And Public Health
In vitro Scavenging Activity of Rosemary Extract and its Activity Against Some Pathogenic Microorganisms
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Rosemary (Rosmarinus officinalis L.) is one of the most economically important species of the family Lamiaceae. Rosemary extract was examined by applying 2.2-diphenyl-1- picrylhydrazyl (DPPH) radical-scavenging assays. The result proved that rosemary extract had a higher antioxidant activity by absorption at a wavelength of 517a nm by using three different concentrations (0.5, 1.0 and 3) mg/ml which performed the absorbance at (2. 314, 0. 211 and 0.296) nm in comparison with control (21.8, 92.2 and 90) nm respectively. Results obtained using chemical detection of the phytochemicals indicated the presence of flavonoids, phenols, saponins, Steroids and cardiac in rosemary water extract. Water extracts of R. officinalis leaves were inves

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Publication Date
Wed Feb 08 2023
Journal Name
Iraqi Journal Of Science
Increasing of Some Medical Flavonoid Compounds of Dodonaea viscosa L. using AgNO3 Nanoparticles In Vitro
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The research was conducted to study the effect of adding different concentrations of AgNo3 Nanoparticles (0,0.5,1.0,1.5,2.0) mg/ l in the production of some secondary metabolic compounds(Quercetin, Luetolin and Apigenin) of plant Dodonaea viscosa L. Quantitative and qualitative analysis of secondary metabolites were estimated by using( HPLC ). The explants from leaves were culture on MS media supplemented with 2mg/l of 2,4-D, 0.5mg/l of NAA and 0.5 mg/l of BA for callus induction. Adding AgNo3 Nanoparticles (2 mg/l) cause in significant increase of Quercetin and Luetolin production, while adding AgNo3 Nanoparticles (0.5mg/l) led to significant increase of Apigenin in callus extract.

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Publication Date
Sun Mar 07 2010
Journal Name
Baghdad Science Journal
Studying the biological activity of some Antimony Compounds with amino acids
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In this work four complexes of antimony were prepared ,Na[SbO(gly)2],Na[SbO(Asp)2],Na[SbO(Tyrosin)2], Na [SbO(phen alanin)2]. by reaction SbOCl with salts amino acids identifiefid these complexes by FTIR ,their conductivity was measured and also their biological activity against two types of bacteria was studied ,they were biologically active.

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Publication Date
Sun Oct 22 2023
Journal Name
Iraqi Journal Of Science
The Effect of Alkaloids Extract of Amaranthus gracilis (L.) on Some Biological Aspects of House Fly Musca domestica(L.)
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Present study is carried out to evaluate the effect of alkaloids extract of
Amaranthus gracilis on some biological aspects of the house fly Musca domestica to
find out the best way for their control. The highest mortality percentage on eggs of
the house fly was 83.3% at concentration of 10 mg/ml followed by 44.4% and
31.1% at 7.5 mg/ml and 5 mg/ml respectively. Results also referred that the
mortality rates of eggs, larvae, pupae were increased with increasing concentration.
The pupal weights were decreased with increasing of concentration.

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Publication Date
Sun Apr 30 2023
Journal Name
Iraqi Journal Of Science
Comparison of the inhibitory effect of the alcoholic extract of pomegranate peel and antibiotics against some intestinal bacterial isolates
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This research included isolation of 18 bacterial isolates from children stool with diarrhea and acute bloody water and under the age of five, if possible get a 9 isolates of the bacterium Escherichia coli and 5 isolates of the bacterium Salmonella typhimurium and 4 isolation of the bacterium Shigella flexneri, subjected all of these isolates tests AGRO and microscopic and biochemical and diagnosed using Vitek2 system. Tested the effectiveness of inhibitory extract alcohol to peel pomegranate Punica granatum L. in the growth of isolates bacterial intestinal and using the diffusion method in drilling Well diffusion as well as determine the focus damper Near Minimum inhibitory concentration MIC and focus killer Near Minimal bactericidal con

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