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ijs-558
Effect of aqueous extract of Agaricus bispporus on lipid profile of female albino mice treated with peroxide
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Agaricus bisporus is cultivated edible mushroom . This study is made to evaluate the  activity of A. bisporus extract  on  lipid profile in mice treated with peroxide.  40 females albino mice were chosen and  divided into 4 groups (ten mice per each group). The first group was treated with normal saline as a control, the second group received 2ml/kg body weight of peroxide , While the third set received 2ml/kg body weight of peroxide plus 25 mg/ml  A bisporus .Besides, the last fourth group received 25 mg/ml  of A. bisporus. The Results have showed a significant increase (p≤ 0.05) in cholesterol(CH) in group 2 (250.01± 1.05)and group3 (204.25±1.80), while there was no significant decrease in CH  level of group 4(170.01±2.01) as compared with control group(184.00± 1.02). As well, there was a significant increase in Low Density Lipoprotein (LDL) in group 2 (159.23±0.9) and group 3 (158.32±2.00), while there was a significant decrease (110.95±1.3) in the level of this parameter in group 4 as compared with the control group(115.98±2.2). Moreover,  there was a significant differences in the levels High Density Lipoprotein ( HDL) ,Very Low Density Lipoprotein (VLDL)  Triglyceride and in all treated groups compared with the control group.

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Publication Date
Sat Oct 01 2011
Journal Name
Baghdad Science Journal
Studying the Effect of Aqueous Extract from Curcuma Longa on Some Parameters of Cytogenetic, Immunity and Fertility in Female Mice
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The research work was conducted to investigate the effect of oral administration of aqueous extract of turmeric at doses of (5, 10) mg/kg body weight for two weeks daily by determining the genotoxic effect (mitotic index), evaluation of immunological effect (IgG, IgM, IgA, C3, C4) and measuring fertility hormones (follicles stimulation hormone/FSH, lutenising hormone/LH) levels with histological examinations of female albino swiss mice ovaries in comparison with control (normal saline). A clear effect in increasing mitotic activity was reveled for both doses in comparison with control. Results also showed a significant increase in the value of all immunological parameters at both doses, in comparison with control. Also, obvious raise was se

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Publication Date
Tue May 30 2023
Journal Name
Iraqi Journal Of Science
Effects of Aqueous Extract of Cumin Seed (Cuminum cyminum) on the Structure and Function of Albino Rat Kidneys Treated with Dibutyl Phthalate
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     This study was aimed to investigate the effects of Cuminum cyminum seed aqueous extract on the function and histological structure of rat kidney treated with dibutyl phthalate (DBP). Eighteen albino rats weighing 190-240g and aged 10-12 weeks were used for this study which went on for 28 days. The rats were divided into three groups (each with six animals): 1st  group: control rats were given food and tap water, 2nd group was given DBP (420mg/Kg. B.W.)  with tap water and diet, 3rd group were fed cumin plant orally at a daily dose of (200 mg/kg B.W.) and DBP (420mg/kg. B.W.) was given with drinking water and fed with diet daily. Kidney and liver function parameters were measured and hi

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Publication Date
Thu Dec 29 2016
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Effect of Antioxidants (Vitamin C and E) on Function of Testes in Albino Mice Treated With Hexavalent Chromium
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   Effect of antioxidants (vitamins C and E) (500mg/kg) was studied on function of testes in albino mice treated with hexavalent chromium (1000ppm). The results showed that exposure to hexavalent chromium caused a significant decrease in body weights, without changes in weight of testes, seminal vesicles and prostate. A significant decrease was observed in the percentage of dead sperms, sperms abnormalities, diameter of seminiferous tubules and the number of leydig cells. Degenerative changes and necrosis were observed in the lumen of seminiferous tubules. Treatment of hexavalent chromium-exposed mice with vitamin C caused improvement in weights and characters of sperms and improvement of the tissue of seminiferous tubules. Tre

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Publication Date
Fri Jan 01 2016
Journal Name
Iraqi Journal Of Science
The Inhibitory Effect of Aqueous Extract of Coriander (Coriandrum sativum L.) Leaves on the Activity of Male Reproductive System of Albino Mice
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The aim of present study to investigate the effect of Coraindrum sativum leaves extract on reproductive activity of male albino mice .Thirty male mice with age of 80-100 day and weight between 25-30 g were divided into three groups: group 1 (untreated), group 2 and 3 were administrated orally for 30 days with aqueous extract of Coraindrum sativum leaves at dose 125 and 250mg/kg.b.w. respectively. The following parameters were evaluated: serum testosterone levels, testes weights, sperm characteristics [motility, viability, spermatozoa, morphology and concentration] and histology changes of the testis. The results showed that the treatment caused highly significant degrease (P<0.01) in testosterone levels and the weight of testes assoc

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Publication Date
Wed Feb 08 2023
Journal Name
Iraqi Journal Of Science
The Inhibitory Effect of Aqueous Extract of Coriander (Coriandrum sativum L.) Leaves on the Activity of Male Reproductive System of Albino Mice
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The aim of present study to investigate the effect of Coraindrum sativum leaves extract on reproductive activity of male albino mice .Thirty male mice with age of 80-100 day and weight between 25-30 g were divided into three groups: group 1 (untreated), group 2 and 3 were administrated orally for 30 days with aqueous extract of Coraindrum sativum leaves at dose 125 and 250mg/kg.b.w. respectively.
The following parameters were evaluated: serum testosterone levels, testes weights, sperm characteristics [motility, viability, spermatozoa, morphology and concentration] and histology changes of the testis. The results showed that the treatment caused highly significant degrease (P<0.01) in testosterone levels and the weight of testes ass

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Publication Date
Sun Mar 02 2014
Journal Name
Baghdad Science Journal
The Effect of Vitamin A on Testis Weight and Sexual Glands on Albino Male Mice Treated with Hexavalent Chromium
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This study was conducted to determine the effect of vitamin A ( 10 mg/kg ) on avearage testis weight and sexual glands ( Prostate and Seminal Vesicle ) for albino male mice treated with Hexavalent chromium ( 1000 ppm ) .The current study 40 mice were divided into fife groups : 1st group treated with distilled water and considered an control group (C) / the 2nd group treated with sesame oil ( T1) / 3rd group was givin hexavalent chromium ( 1000 ppm ) (T2) / 4th group treated with vitamin A ( 10 mg / kg ) and exposed to hexavalent chromium ( 1000 ppm ) (T3) / 5th group treated with vitamin A ( 10 mg kg ) (T4) . The expermint lasted 35 day . the results showed a significant ( P ? 0.05 ) decrease in avearage testis weight and sexual glan

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Publication Date
Sun Jan 30 2022
Journal Name
Iraqi Journal Of Science
Effects of Gel Extract from Aloe Vera Cultivated in Iraq on Blood Glucose Level and Lipid Profile in Induced Diabetic Mice
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     In Iraq; there is a great demand for handling  some epidemic diseases such as hyperglycemia and hyperlipidema through searching some medical plant extracts which the country is rich with and contains an important phytochemicals that may solve  the incidence of such cases. Aloe vera that cultivated in Iraq, is known to be rich with biological active constituents.    The aim of  the  present study; the plant gel extract was subjected  to treat an induced diabetic lab mice through injecting  streptozotocin dose with  high fatty food to elevate lipid profile before induction of the gel oral treatment of the plant. In the study results: the oral administration of A.ver

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Publication Date
Sun Sep 03 2017
Journal Name
Baghdad Science Journal
A study of histological changes in the Diaphragm of male albino mice administered with aqueous extract of chamomileflowers Chamomillarecutita
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The chamomile is one of the most important medicinal plants recommended for treatment of asthma and some respiratory system diseases. This research was designed to research the effects of aqueous extract of chamomillarecutita on histological structure of Diaphragm of albino mice. The study included 40 male albino mice Musmusculus, their age ranged from (5-7) weeks.The mices were divided randomly to 5 groups and oral administered with 1 ml every day for 10 days:- First Group G1: consider as control group and treated with normal saline,Second Group G2: was treated with aqueous extract of chamomile with concentration of 3 gm /100 ml D.W, Third Group G3: was treated with aqueous extract of chamomile with concentration of 5 gm /100 ml D.W.Fourth

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Publication Date
Sun Jan 04 2015
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Effect of Green Lean Body Capsules on Body Weight, Lipid Profile, and Renal Physiology and Histology in Albino Rats
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Background: Many anti-obesity medicines have been increased in recent years to solve the problem of obesity; among these medicines are Green Lean Body Capsules (GLBCs) which contain green plants and fruits extract.
Objective: This study was designed to evaluate the effects of daily oral consumption of GLBCs on level of serum lipids, renal function tests, and the histological structure of the kidney in albino rats.
Materials and Methods: Twenty adult albino male rats weighing 240-260 g were divided into 2 equal groups: control group and GLBCs-treated group. During the 4-weeks treatment, each rat in the GLBCs-treated group was orally administered with 20 mg/kg B.W. of GLBCs, while the control rats were orally

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Publication Date
Wed Apr 04 2012
Journal Name
The Iraqi Journal Of Veterinary Medicine
Toxicopathological study of aqueous extract of beetle cocoon Larinus maculatus F. on some internal organs in male albino mice
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The present study was carried out to investigate the effect of oral administration of hot aqueous extract of beetle cocoon Larinus maculatus Faldermann, in a two doses 50 and100mg/Kg/Bw for 25 and 45days respect- tively on some organs such as liver, lung, kidney, intestine, heart, spleen, and brain in male mice Mus musculus. The results indicated that there were toxicopathological changes in many tissues of experimental animals. Histo -pathological changes was dose and period dependent . It was found that the aqueous extract of beetle cocoon has undesirable effect at the administered doses, since the raw extract of this cocoon is currently being used in Folk medicine as treatment for cough, bronchitis in Iraq. This study revealed that the l

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