The objective of this study was to assess the levels of antiMullerian hormone (AMH), Follicle stimulating hormone (FSH), testosteron, luteinizing hormone (LH), and estradiol (E2) as markers of spermatogenesis between fertile and infertile males. This study was conducted at (AlRamadi Teaching Hospital for maternity and children) and included 136 males partners of infertile couples. Samples were classified according to the WHO criteria of semen analysis into three groups; Azoospermia, Oligospermia, and normal(control). Assay levels of these hormones were made in the serum and the semen of each sample. The results showed that the level of AMH in serum samples was non-significantly decreased (P>0.05) in both Azoospermia and Oligospermia groups compared to control (6.74±3.21 ng/ml and 6.01±0.25 ng/ml vs. 12.81±7.69 ng/ml). While FSH and LH levels, there were non-significantly(P > 0.05) increased in both azoospermia and Oligospermia compared to control (FSH: 12.11±8.14 mIU/ml and 7.22±6.06 mIU/mlvs.3.14±1.27 mIU/ml; LH: 10.04±7.23 mIU/ml and 7.62±3.30 mIU/ml vs.5.57±2.03mIU/ml).In addition, there were non- significant differences (P> 0.05) of testosterone hormone level among the studied groups. Such, there was a non-significant decreased level of E2 (P> 0.05) in both Azoospermia and Oligospermiagroups compared to control (170.49±37.57 ng/ml and 137.20±53.92 ng/ml vs. 194.91±41.66 ng/ml).İn contrast to semen samples, the results of AMH showed a significant (P< 0.05) decreased level in both Azoospermia and Oligospermia compared to control (8.24±4.17 ng/ml and 8.85±4.79 ng/ml vs. 13.33±0.77 ng/ml). FSH level was non-significant (P> 0.05) increased in Azoospermia and Oligospermia compared to control (3.97±1.91 mIU/ml and 4.09±2.50 mIU/ml vs. 2.47±1.29 mIU/ml). Such, there were non-significant (P> 0.05) increased levels of LH and testosterone hormones in both Azoospermia and control compared to Oligospermia (9.35±6.02 mIU/ml and 5.99±4.43 mIU/ml vs. 4.06±2.82 mIU/ml), and significant (P< 0.05) increased level of E2 in both Azoospermia and Oligospermia compared to control (241.36±35.32 ng/ml and 220.86±48.96 ng/ml vs. 170.71±73.52 ng/ml).The study concluded that the AMH, FSH and E2 hormones levels in serum and semen samples may have been associated with the sperm production and may be a good marker for spermatogenesis, as well as Sertoli cell development. In addition, the age played a critical role in the level of the studied hormones.
Folate metabolism is fundamental and essential for DNA structure synthesis and repair. Change in genes that participate in folate metabolism can be linked with different types of malignant tumor, Therefore, this study was conducted to find out the association between methylenetetrahydrofolatereductaseMTHFR gene polymorphisms and risk of breast cancer in a sample of Iraqi patients. One Single Nucleotide Polymorphism ( SNP) including MTHFR C677T was calculated using a tetra primer ARMS PCR experiment assay. The results explained that (MTHFR C677T) consists of three genotype (CC, CT, TT), The CC genotype was the most frequent in patients and control group ( 40.00%) and(60.00%) ,respectively, while the lowest frequency was for TT genotype(26
... Show MoreAlterations of trace element concentrations adversely affect biological processes and could promote carcinogenesis. Trace element deficiency or excess is implicated in the development or progression of some cancers like colorectal cancer. The aim of the present study was to compare the serum copper (Cu) and zinc (Zn) concentrations in patients with colorectal cancer from Iraqi male patient with those of healthy subjects. During the period of March 2015 until august 2015, a total of 25 patients with metastatic colon cancer and 20 healthy volunteers were enrolled from the Al-Kadhimia Teaching Hospital after the diagnosis using a histopathological examination for the malignant tumor; their age was between (38-60) years. Higher levels o
... Show MoreAlterations of trace element concentrations adversely affect biological processes and could promote carcinogenesis. Trace element deficiency or excess is implicated in the development or progression of some cancers like colorectal cancer. The aim of the present study was to compare the serum copper (Cu) and zinc (Zn) concentrations in patients with colorectal cancer from Iraqi male patient with those of healthy subjects. During the period of March 2015 until august 2015, a total of 25 patients with metastatic colon cancer and 20 healthy volunteers were enrolled from the Al-Kadhimia Teaching Hospital after the diagnosis using a histopathological examination for the malignant tumor; their age was between (38-60) years. Higher
... Show MoreIn this study forty mature albino rats were used wich were randomly divided into five groups ,four groups were adminstrated Phoenix dactylifera pollen grains suspension at concertenrations (18,54,108,and 216)mg/ kg body weight by oral administration while the fifth group was considered as a control group.Experiment continued for 40 days then rats were sacrificed and samples of blood were collected for determination of some biochemical parameters (total protein ,total cholesterol ,LDLc and HDLc).Testis were removed for preparation histological sections to measures the diameters of seminferous tubules ,thickness of seminiferous epithelium and the numbers of spermatogenic cells.
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This work studies the role of serum apelin-36 and Glutathione S-transferases (GST) activity in association with the hormonal, metabolic profiles and their link to the risk of cardiovascular disease (CVD) in healthy and patients' ladies with polycystic ovary syndrome (PCOS). A total of fifty-four (PCOS) patients and thirty-one healthy woman as a control have been studied. The PCOS patients were subdivided on the basis of body-mass-index (BMI), into 2-subgroups (the first group was obese-PCOS with BMI ≥ 30 and the second group was non-obese PCOS MBI<30). Fasting-insulin-levels and Lipid-profile, Homeostatic-model assessment-of-insulin-resistance (HOMA-IR), follicle-stimulating-hormone (FSH), luteinizing-hormone (LH), testosterone and
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Public spending represents the government’s financial leverage and has a significant impact on real and monetary economic variables, and one of these effects is the effect of public spending on the exchange rate as an important monetary variable for monetary policy, As we know that public spending in Iraq is financed from oil revenues sold in US dollars, and the Ministry of Finance converts the US dollar into Iraqi dinars to finance the government's need to spend within the requirements and obligations of the state's general budget, And converting the US dollar into Iraqi dinars has an impact on the parallel exchange market, even if there is a contractual exchange rate between the Ministry of Finance and the Central Bank of Iraq to
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Anastatica hierochuntica is believed to be very useful in Arab countries for treating various health disorders. The aqueous extract of Anastatica hierochuntica was investigated for its effects on hormones in mice females. the aqueous extract of plant at a dose level of 100mg/1mL showed significant increase (p<0.05) on levels of hormones LH, FSH, PRL level and PRO level. Clomid treated group showd significant increase in LH, FSH, and PRL while there was non-significant increase in PRO. From the above results, it is concluded for the first time that aqueous Anastatica hierchuntica extract offers significant effect of LH, FSH, PRL, and PRO in this mice females scompared with control.
The aim of this study is to find a relationship between oxidative stress and adiponectin in Iraqi patients with acromegaly. The present study included 30 patients with acromegaly disease attending at Al-Yarmuk teaching hospital , and 30 healthy individuals as a control group.The two groups with ages ranging (30-55) years. The results revealed a highly significant elevation in all parameters (GH,IGF-1 , adiponectin , malondialdehyde , and peroxynitrite ) levels in sera of patients when compared with healthy control .It can be concluded that oxidative stress (malondialdehyde and peroxynitrite ) may be valuable in detecting of endocrine diseases like acromegaly .
The aim of this study is to find a relationship between oxidative stress and adiponectin in Iraqi patients with acromegaly. The present study included 30 patients with acromegaly disease attending at Al-Yarmuk teaching hospital , and 30 healthy individuals as a control group.The two groups with ages ranging (30-55) years. The results revealed a highly significant elevation in all parameters (GH,IGF-1 , adiponectin , malondialdehyde , and peroxynitrite ) levels in sera of patients when compared with healthy control .It can be concluded that oxidative stress (malondialdehyde and peroxynitrite ) may be valuable in detecting of endocrine diseases like acromegaly .
The scholastic view of public religion differed, and this difference was on two extremes. All economic schools agreed that public debt is a monetary liquidity that was unjustly deducted from the income and output cycle as a result of the imbalance in the economic balance and the departure from the conditions of balance between aggregate demand and aggregate supply. Debt is a waste of financial resources allocated to productive accumulation. Except for the Keynesian school, which considers public debt to be an addition to aggregate demand after the decline in the role of the private sector in investment as a result of pessimistic expectations that warn of signs of economic contraction. Public debt is linked to the ex
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