The study was aimed to investigate the association between IL-10 (-592A/C) gene polymorphism with the progression of type 2 diabeteis mellitus in Basrah Province. This study included (100) subjects (30) person as a control group and (70) patients with T2DM. The patients were distributed as two groups according to Their gender and duration of the disease: group for short duration (≤ 5 years) and group for long duration( >5 years). Lipid profile and glucose concentrations were measured by COBAS analyzer while IL-10 (-592A/C) gene polymorphism was genotyped by using (RFLP-PCR) technique. CC genotype frequency showed a significant decrease while CA genotype revealed significant increase ( p≤0.05) in T2DM compared with controls .No significant differences were observed in the allelic frequencies between both groups. Gender and duration of diabetes didn’t show any significant differences. There is significant association between CA genotype with the risk of T2DM (OR=1.50, 95% CI=1.035-2.173). We concluded that IL-10 (-592A/C) gene polymorphism contribute in development of T2DM.
The association of IL-10 (-592A/C) gene polymorphism with progression of Type 2 Diabetes Mellitus in Basrah Province-Iraq
IL-10 -592A/C
gene polymorphism
T2DM
Publication Date
Wed Jan 20 2021
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
αg_Ị-open sets and αg_Ị-functions
αg_Ị-closed set
αg_Ị O-functions
αg_Ị C-functions
αg_Ị-continuous function
Strongly αg_Ị-continuous function
αg_Ị-irresolute function
ideal.
The objective of this paper is to show modern class of open sets which is an -open. Some functions via this concept were studied and the relationships such as continuous function strongly -continuous function -irresolute function -continuous function.
