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Biochemical and Genetic Study in Blood of β– Thalassaemia Children in Mosul City, Iraq
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The present study aimed to demonstrate the extent to which the activity of a number of enzymes and genetic variation of β-globin genes were affected in the blood of 65 children with β - thalassemia major of both sexes. The patients, with an age range of 2 – 15 years, were registered in the Thalassemia Center at Ibn Al-Atheer Teaching Hospital for Children in the city of Mosul / Iraq. They were under continuous treatment after being diagnosed by specialist doctors. The study also involved 30 healthy children of both sexes with the same age range who were considered as a control group.

       The results showed significant increases (p≤0.05) in the activities of alanine transaminase (ALT), aspartate  transaminase (AST), alkaline phosphatase (ALP), glucose 6- phosphate dehydrogenase (G6PD),  and adenosine deaminase (ADA) in the serum of treated patients by 73% , 53%, 8%, 9%, and 54%, respectively, compared with the healthy children group. Also, the results showed significant increases in the activities of G6PD  and ADA in the red blood cells (RBCs) of the patients by 7% and 43%, respectively,  compared with the control group.

     When determining the genetic variation of the β-globin gene depending on the PCR technique, the results did not show any genetic variation in the size of PCR band. However, the results of the sequencing showed variations in the nucleotides that included the conversion of the nucleotides (A) to (C) in position (250), (T) to (C) in position (426), (C) to (A) in position (623), (G) to (A) in position (630), and (T) to (A) in position (724). Also, the results demonstrated the detection of three transversion mutations and two transition mutations in β-globin gene in the children with β-thalassemia.

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Publication Date
Wed Mar 27 2019
Journal Name
Iraqi Journal Of Science
Efficiency of Thematic Mapper Data for Detecting the Changes of Land Use -Land Cover in Mosul Lake and Surrounding Area Northern Iraq
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The study area lies in the northern part of Iraq, This study depends on one scene of Thematic Mapper (TM5) data of Landsat, these data are subset by using region of interest (ROI) file within the ERDAS 9.2 software. RS and GIS have been used as tools for detecting the desertification during the periods 1990-2000-2009 by using Normalized Difference Vegetation Index NDVI, Water Index WI and Barren Land Index BLI. The indicators of Desertification which used in this study for period  1990-2000 and 2000-2009 are represented by decrease the vegetation cover and increase water body and barren land.

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Publication Date
Fri Aug 28 2020
Journal Name
Iraqi Journal Of Science
The hydrochemistry of Tigris River in Baghdad city, Iraq
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The primary objective of this study was to investigate the current status of water-quality conditions and assessment it in the Tigris River, Baghdad, Iraq, and to determine how those conditions are changing over time of pollution if any. A series of Hydrochemical tests were carried out to ascertain the influence of major Cations and Anions, Total Dissolved Solids (TDS), Electrical Conductivity (EC) and Potential of hydrogen (pH) on the quality of water. To assess the environmental pollution of the study area: 34 water samples were collected along Tigris River from north to south Baghdad City; 17 on January 2019 and 17 on April 2019. Result of the test were compared with the World Health Organization standards, and showed that all the

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Publication Date
Sat Jan 01 2022
Journal Name
Open Engineering
Geotechnical correlations of soil properties in Hilla City – Iraq
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Abstract<p>In this research, the geotechnical properties of the soil profile in Hilla city within Babylon Governorate in the middle parts of Iraq are described. The geotechnical data at the specific sites were collected from some geotechnical investigation reports performed at some selected locations. This article is devoted to studying the distribution of soil properties (the physical and mechanical) in the horizontal and vertical directions. Moreover, a correlation between different physical and mechanical properties is performed. The correlation is executed using statistical analysis by Microsoft Excel Software (2016). From the regression results, it was found that the nature of the soil is c</p> ... Show More
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Publication Date
Sat Jan 01 2022
Journal Name
Open Engineering
Geotechnical correlations of soil properties in Hilla City – Iraq
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Abstract<p>In this research, the geotechnical properties of the soil profile in Hilla city within Babylon Governorate in the middle parts of Iraq are described. The geotechnical data at the specific sites were collected from some geotechnical investigation reports performed at some selected locations. This article is devoted to studying the distribution of soil properties (the physical and mechanical) in the horizontal and vertical directions. Moreover, a correlation between different physical and mechanical properties is performed. The correlation is executed using statistical analysis by Microsoft Excel Software (2016). From the regression results, it was found that the nature of the soil is c</p> ... Show More
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Publication Date
Wed Mar 10 2021
Journal Name
Baghdad Science Journal
5'-nucleoridase activity in sera from iraq children with leukemia
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Enzyme activity were studied in the sera of children with leukemia than healthy children, where 31 cases were studied, including 21 cases of patients with acute lymphatic leukemia

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Publication Date
Wed Dec 14 2016
Journal Name
Journal Of Baghdad College Of Dentistry
Dental Caries and Treatment Needs among Kindergarten Children in Al-Basrah Governorate/Iraq
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Background: Dental caries is a disease occurs in the world in both developed and developing countries, it is still widespread among children and it can be controlled but not eliminated , most of tooth loss occurs due to dental caries and its complications. The aim of this study was to estimate the occurrence, and severity of dental caries and treatment needs among kindergarten children in Al-Basrah governorate. Materials and methods: The sample consisted of 1000 kindergarten children at age of 4-5 years old (445 boys and 555 girls) from urban areas in Al-Basrah city. Diagnosis and recording of dental caries and treatment needs were done according to the criteria of WHO (1987). Results: The percentage of dental caries was (80.8%) of the tota

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Publication Date
Thu May 04 2023
Journal Name
Biomedicine
Assessing the complete blood count in Graves’ ophthalmopathy patients treated with RAI-131 in Iraq
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Introduction and Aim: Graves ophthalmopathy is one of the pandemic public health disorders in Iraq. The current investigation attempts to determine the variation in the complete total blood cells on the recovery of individuals with Graves' ophthalmopathy following low and high-dose Radioactive Iodine 131 (RI-131) exposures.   Materials and Methods: The complete blood CBC level in people with Graves' illness and healthy, normal controls were quantitatively identified using the CBC counter. Thyroid stimulating hormone was utilized to compare the recovery of ophthalmopathy patients in comparison to a control group.    Results: In comparison to healthy controls, patients with Graves' ophthalmopathy disease who received 10 mci of RAI-

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Publication Date
Sun Sep 01 2013
Journal Name
Baghdad Science Journal
Biochemical Study of Gonad Hormones in Sera of Iraqi Patients with Thyroid Disorder
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The objective of this study was to evaluate the alteration in levels of gonado trophins hormones i.e.,Leutizing (LH),Follicular(FSH) in sera of patients with thyroid disorders and molecular binding study of (LH ,FSH) with their antibodies The study was conducted at the specialized center for endocrinology and diabetes from January / 2009 to March / 2010.Two hundreds and twenty three Iraqi subjects, 109 patients with thyroid disorders at age range between (40-50) years and 114 healthy individuals as control group were included in this study.The majority of patients were female with hyperthyroidism and (49.54 % ) were at age range between(40 - 50) years. The levels of hormones(LH,FSH.tri iodothyronine(T3).thyroxine(T4), thy

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Publication Date
Sun Jun 07 2009
Journal Name
Baghdad Science Journal
Biochemical study of glutathione reductase (GSH-Red) in Tissue Homogenate of Breast Tumors
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Breast tumor patients generally have more oxidative stress than normal females. This was clear from significant decrease (P<0.05) in tissue GSSG-Red activity. The study had found that free radicals in malignant breast tumors were higher than benign tumors, therefore the GSH- Red might be used as markers for prognosis of the disease. Results of molecular characterization show optimum enzyme concentration substrate conc., optimum pH, temperature & time & effect of some (chemotherapies in constant conectrations) for GSSG-Red activity.

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Publication Date
Mon Mar 08 2021
Journal Name
Baghdad Science Journal
Effect of alkaloid and phenolic extract administration oi Allium cepa L Ù  on some biochemical parameters of blood on albino mice
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؛ ١٨his study male and female albino mice werdministr^d doses of alkaloid and phenolic extracts of Allium cepa at doses of( 25 ,50,100, 200) mg / kg of( body weight). males and females were divided into four groups and each croup comprised mice were injected intra^ritonially daily for one week and orally ٢٠٢ one month . After which animals were killed and the serum was separated for biochemical analysis (total blood suger, total protein , otal cholesterol). Results showed significant decrease ( p< 0,05) in the total blood suger and total cholesterol on the serum of both males and females and significant increase( p< 0,05) in the total serum protein of both males and females of the two types of injection and oral administr

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