Tropical illnesses caused by parasites proceed to cause socioeconomic devastation that reverberate worldwide protozoan parasites, like Leishmania. This parasite has an enormous public health problem in many countries. There is a growing requisite for new control methods for many of these illnesses due to the increasing drug resistance showed by the parasites and problems with drug poisonousness. In this study, fifty-five patients (burns and wounds) were collected from patients from Al-Yarmouk Hospital and Teaching Baghdad Hospital during the period from November, 2015 to January, 2016. Cultural and morphological characteristic examination, biochemical tests were conducted and confirmed the diagnosis by antibiotics sensitivity test and Vitek-2 system. The results identified thirty-three Staphylococcus aureus and thirty Pseudomonas aeruginosa from skin burn and wounds. Vitek 2 system gave confirmation of positive results for both strains with a probability 98-99%. The S. aureus isolate (S3) and P. aeruginosa (P 5) was chosen among bacterial isolates as a good producer for crude both bacteriocins according to their widest inhibition zone by well diffusion assay WDA. Two steps method extraction were used for bacteriocin purification, first via ammonium sulphate at 70% and next step by Sephadex G-50 gel filtration chromatography. The two new drugs staphylococcin and pyocin at different concentrations was used for the treatment of L. tropica and L. donvani. All concentration of Staphylococcin showed no inhibitory activity on promastigotes of L. tropica and L. donvani. While the concentration of 32.5 µgmL-1 of pyocin showed the maximum cytotoxic effect on promastigotes of L. tropica and L. donovani, where the inhibition rate (IR%) were 87.1% and 87.9% respectively. As part of the research objectives is the discovery of new treatments against leishmaniasis also benefit from improved models.
Sixty urine samples were collected from women with urinary tract infection in different ages. The aims of this study were determined the dominancy of pathogens isolated from urine of women with UTI and evaluating the antibacterial activity of Rosmarinus officinalis L. essential oil against these pathogenic isolates. Identification of bacteria was done on Chromogenic orientation agar while disc diffusion method was used for determination the sensitivity of bacterial isolates to antibiotics and Agar well diffusion method was used for evaluation the antibacterial effect of Rosemary essential oil on these isolates. The results showed that 50% of women infected with Escherichia coli, it was dominants in ages above 15 years old while Staphylococc
... Show MoreEffect Anti-Mullerian Hormone (AMH) on thyroid levels in patients with and
without polycystic ovarian syndrome PCOS was studied, The results showed an
increase in AMH ,T3 ,T4 with increase of age while TSH , BMI decreased with
increase of age comparing to control in hyperthyroidism with PCOS patients.
Otherwise an increase in AMH, TSH, BMI, T3 and T4 with increase of Age
compared to healthy group in hyperthyroidism without PCOS. Effect of ovarian
hormones (AMH) on inventory levels of thyroid and perturbations in terms of
increases and its impact obesity as well as fertility in women was declared in this
research. Serum Anti-Müllerian Hormone (AMH) was assessed using enzyme linked
immunosorbent kit [Elisa] whil
The aim of the present study was assess the antimicrobial effect of
Peganumharmala L seeds extracts by ethanol (80%) on gram negative and gram
positive bacteria and four concentrations (25, 50, 75 and 100) mg/ml were prepared.
Four clinical isolates of bacteria were used; two were positive and two were
negative bacteria; that include: Bacillus, Staphylococcus aureus, Pseudomonas
aeruginosa and Escherichia coli. The results showed that all concentration that have
been used had antimicrobial effect against gram negative and gram positive bacteria
and the best concentration that have the best antimicrobial effect was 100 mg/ml and
the effect of alcoholic extraction was greater on gram positive bacteria than gram
n
(5)
(5)
The compound [G1] was prepared from the reaction of thiosemicarbazide with para-hydroxyphenylmethyl ketone in ethanol as a solvent. Then by sequence reactions prepared [G2] and [G3] compounds. The compound [G4] reaction with ethyl acetoacetoneto synthesized compound [G6] and acetyl acetone to synthesized compound [G5]. Reaction the [G3] with two different types of aldehydes in the present of pipredine to form new alkenes compounds [G7]and [G8].The compound [G3] reacted with hydrazine hydrate to formation[G4] with present the hydrazine hydrade 80% in (10) ml of absolute ethanol. Latter the compound [G4]reacted with different aldehydes with present the glacial acetic acid and the solvent was ethanol to formed the Schiff bases compounds[G9] an
... Show MoreThe compound [G1] was prepared from the reaction of thiosemicarbazide with para-hydroxyphenylmethyl ketone in ethanol as a solvent. Then by sequence reactions prepared [G2] and [G3] compounds. The compound [G4] reaction with ethyl acetoacetoneto synthesized compound [G6] and acetyl acetone to synthesized compound [G5]. Reaction the [G3] with two different types of aldehydes in the present of pipredine to form new alkenes compounds [G7]and [G8].The compound [G3] reacted with hydrazine hydrate to formation[G4] with present the hydrazine hydrade 80% in (10) ml of absolute ethanol. Latter the compound [G4]reacted with different aldehydes with present the glacial acetic acid and the solvent was ethanol to formed the Schiff bases compounds[G9] an
... Show MoreThe aim of the present study was to characterize the Iraqi Tribulus terrestris for the presence of biologically active phyto-chemicals using methanolic extracts of the plant (aerial parts) by Gas Chromatography –Mass spectrometry (GC/MS), while the mass spectra of the compounds found in the extract was matched with the National Institute of Standards and Technology (NIST) library , in addition to study the antioxidant activity of plant extract , results confirmed the presence of therapeutically potent compounds in the Iraqi Tribulus terrestris extract predominantly alkaloids, flavonoids, saponins, tannins and terpenoids. Antioxidant potential of Iraqi Tribulus terrestris
... Show More
(2)
Many clinical isolates of proteus spp. (30 isolates of P
mirabilis and 30 isolates of P. vulgaris) from patients with urinary
tract infections (UTIs) were examined for their ability to produce
proteolytic enzymes and their ability to form swarming growth. Most
(90%) of P. mirabilis and 60% of P. vulgaris isolates secreta
proteolytic enzymes. A strong correlation was found between the
ability of a strain to secreted proteases and it's ability to form
swarming growth. Non- swarming isolates invariably appeared to be
non- proteolytic. However, some isolates (12 isolates of P. vagaries)
were non- proteolytic even when they formed swarming growth
New sulfonamide derivatives comprising azide, 1, 2, 3- triazole, azo , chalcone and Schiff base moieties had synthesized. The structures of the new compunds have been confirmed byFT-IR and ¹H-NMR spectra. The synthesized derivatives have been screened for antimicrobial and in vitro antioxidant properties. The results of this investigation revealed that the newly synthesized compounds have good antimicrobialand antioxidant activities.
Phthalimide formation of Phthalic anhydride with various amines using microwave or without a method with the difference of the catalyst used in a prepared Phthalimide, either structure general are C6H4CONRCO and used as starting materials in synthesis several compounds derivative phthalimides are an important compounds because spectrum wide biological activities including Antimicrobial activity, anticonvulsant activity, Anti-inflammatory activity,Analgesic activity, Anti- influenza activity and Thromboxane inhibitory activity