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Evaluation of the Biological Activity of Nickel Oxide Nanoparticles as Antibacterial and Anticancer Agents

In the present study, nickel oxide nanoparticles (NiO NPs) were evaluated as an antibacterial and anticancer agent. The nanoparticles of nikel oxide were synthesized using aloe vera leaves extract and characterized with AFM (showing an average diameter of 45.11 nm), XRD and FE-SEM analyses. Three different concentrations (125, 250 and 500 µg/ml) were prepared from the synthesized NiO NPs and investigated for their potential antibacterial activity against both Enterococcus faecalis (Gram-positive bacteria) and Acinobacter baumannii (Gram-negative bacteria). While cytotoxicity and apoptotic activity were measured on both MCF-7 and AMJ13 cancer cell lines by  MTT and caspase-9 luminescence assays. The results showed that NiO NPs inhibit bacterial growth, as indicated by large inhibition zones  against both tested bacteria, with all studied concentrations. Moreover, the results of cytotoxicity and caspase-9 activity assays were in concordance with those of  antibacterial activity, showing high cytotoxicity and apoptotic effects against both of the studied cancer cell lines and with all the tested concentrations of NiO NPs. Both the antibacterial and anticancer activities of NiO NPs were dose-dependent. 

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Publication Date
Wed Nov 20 2024
Journal Name
Journal Of Baghdad College Of Dentistry
Assessment of the relationship between maxillary sinus floor and maxillary posterior teeth root apices using spiral CT scan

Background: The purpose of this study is to investigate the relationship between the roots of the maxillary posterior teeth and the maxillary sinus using spiral computed tomography, and measured the distances between the roots of the maxillary posterior teeth and the sinus floor. Materials and Methods: The sample of the present study was a total of 120 Iraqi subject (60 males & 60 females) aged (20-60) years old, who admitted to spiral Computed Tomography scan unit in AL-Zahraa hospital in AL-Kut city to have Computed Tomography scan of the brain and paranasal sinuses who had complaints of headaches or with suspicion of sinusitis but without pathological findings in maxillary sinuses. From November 2012 to April 2013, CT sagittal reconstruc

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Publication Date
Fri Jul 01 2022
Journal Name
Iraqi Journal Of Science
Core Polarization Effects on the Inelastic Longitudinal Electron Scattering Form Factors of Ti 48,50 and Cr 52,54 nuclei

In this paper, inelastic longitudinal electron scattering form factors C2 and C4
transitions have been studied in Ti 48,50
and Cr 52,54
nuclei with the aid of shell
model calculations. The core polarization transition density was evaluated by
adopting the shape of Tassie model togther with the derived form of the ground state
two-body charge density distributions (2BCDD's). The following transitions have
been investigated; 0 2 2 2 1 1
   and 0 2 4 2 1 1
   of Ti 48 , 0 3 2 3 1 1
   and
0 3 4 3 1 1
   of Ti 50 , 0 2 2 2 1 1
   and 0 2 4 2 1 1
   of Cr 52 and
0 3 2 3 1 1
   and 0 3 4 3 1 1
   of Cr 54 nuclei. It is fou

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Publication Date
Fri Feb 01 2019
Journal Name
Journal Of Plastic, Reconstructive & Aesthetic Surgery
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Publication Date
Tue Dec 01 2020
Journal Name
The Saudi Dental Journal
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Publication Date
Fri Jun 15 2018
Journal Name
Journal Of Baghdad College Of Dentistry
Assessment of Dental Implant Site Dimensions And Alveolar Bone Density in The Mandible Using Cone Beam Computed Tomography

Background: The quantity and the quality of available bone, influence the clinical success of dental implants surgery. Cone beam Computed tomography is an established method for acquiring bone images before performing dental implant. Cone beam computed tomography is an essential tool for treatment planning and post-surgical procedure monitoring, by providing highly accurate 3-D images of the patient's anatomy from a single, low-radiation scan which yields high resolution images with favorable accuracy. The aim of study is the Measurement of alveolar bone (height and buccolingual width) and density in the mandible among Iraqi adult subject using CBCT for assessment of dental implant site dimensions. Material and method: The study sample in

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Publication Date
Thu Jul 01 2021
Journal Name
Iraqi Journal Of Science
The Influence of NMI against Modularity in Community Detection Problem: A Case Study for Unsigned and Signed Networks

Community detection is useful for better understanding the structure of complex networks. It aids in the extraction of the required information from such networks and has a vital role in different fields that range from healthcare to regional geography, economics, human interactions, and mobility. The method for detecting the structure of communities involves the partitioning of complex networks into groups of nodes, with extensive connections within community and sparse connections with other communities. In the literature, two main measures, namely the Modularity (Q) and Normalized Mutual Information (NMI) have been used for evaluating the validation and quality of the detected community structures. Althoug

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Publication Date
Sat Apr 30 2022
Journal Name
Iraqi Journal Of Science
Geochemistry of the Middle Eocene Gercus Sandstone, Shaqlawa Area, Northern Iraq: Implications for Provenance, Tectonic Setting and Paleoweathering

    The study of the geochemical characterization of sandstone rocks contributes to understand the nature of the source rocks, their tectonic setting and the effects of paleoclimate and paleo-weathering. Accordingly, twenty sandstone samples from the red sandstone units of the Gercus Formation were collected from the northeastern limb of Safin Anticline at Shaqlawa Area – Northern Iraq. The studied sandstone samples show depletion in major, trace elements contents, except for CaO, MgO and Ni, Co and Cr respectively, and general depletion in the rare earth elements (REE) contents. Major element geochemistry indicates that the red bed sandstones of the Gercus Formation are of an oceanic island arc (OIA) tectonic setting. On the other

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Publication Date
Thu Sep 30 2021
Journal Name
Iraqi Journal Of Science
Evaluating the in vitro Cytotoxicity of Thymus vulgaris Essential Oil on MCF-7 and HeLa Cancer Cell Lines

     Thyme essential oil (TEO) was extracted from dried leaves of Thymus vulgaris. The air-dried aerial parts of the plant produced 1.0% yield of TEO. The detection of this essential oil’s compounds was performed by GC-MASS. The cytotoxic activity of TEO was evaluated against two human cancer cell lines, namely HeLa (human epithelial cervical cancer) and MCF-7 (human breast carcinoma). Cells grown in 96 multi-well plates were treated with six concentrations of EO (6.25, 12.5, 25, 50, 100, 200 ppm) and incubated at 37 °C for 72 hrs. Cancer cell lines elicited various degrees of sensitivity to the cytotoxic effect of essential oil. The TEO exhibited significant differences (p≤ 0.01) between the effects of

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Publication Date
Wed Dec 18 2019
Journal Name
Baghdad Science Journal
The Continuous Classical Boundary Optimal Control of Couple Nonlinear Hyperbolic Boundary Value Problem with Equality and Inequality Constraints

The paper is concerned with the state and proof of the existence theorem of a unique solution (state vector) of couple nonlinear hyperbolic equations (CNLHEQS) via the Galerkin method (GM) with the Aubin theorem. When the continuous classical boundary control vector (CCBCV) is known, the theorem of existence a CCBOCV with equality and inequality state vector constraints (EIESVC) is stated and proved, the existence theorem of a unique solution of the adjoint couple equations (ADCEQS) associated with the state equations is studied. The Frcéhet derivative derivation of the "Hamiltonian" is obtained. Finally the necessary theorem (necessary conditions "NCs") and the sufficient theorem (sufficient conditions" SCs") for optimality of the stat

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Publication Date
Thu Apr 27 2023
Journal Name
Journal Of The Faculty Of Medicine Baghdad
The Use of Off-label and Unlicensed Drugs for Neonates: A Report from a Teaching Hospital in Baghdad

Background: Neonates who are admitted to hospitals will need various drugs. The use of unlicensed or off-label drugs without scientific evidence makes this exposure unsafe.

Aim of study: We aimed to assess the use of drugs for neonates based on the British National Formulary for Children and IBM Micromedex Neofax.

Patients and methods: This is a descriptive study which reviewed the clinical files of enrolled neonates who have stayed in the hospital for more than 24 hours and received at least one drug. It was conducted in the neonatal care unit of the Children Welfare Teaching Hospital/ Medical City Complex in Baghdad during the period from 1st of January to 30th of June/20

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