The aim of this study is the determination of the anti-adhesion activity of active compounds extracted from plants in the inhibition of adhesion ability of C. albicans that is used as a virulence factor for infection. Adherence to host surfaces is a primary factor in the colonization of human tissues by fungi, which can also adhere to the surfaces of medical devices and form biofilms. Medicinal plants possess therapeutic properties or beneficial pharmacological effects on the body. A total of one hundred samples were collected from female patients with vaginal infection in two hospitals in Baghdad city for three months. The fungi were isolated and identified by microscopic morphology, morphological features on culture media, and Vital Index of Traditional Environmental Knowledge (VITEK 2) System. Extraction and purification of plant active compounds, vasicine from Adhatoda vasica and gallic acid from Punica granatum L. , were performed. The active compounds were used as anti-adhesion factors and the minimum inhibition concentration (MIC) against Candida albicans was determined. We also used the antifungal drug fluconazole for comparison as a control. The results of vaginal discharge characterization of clinical samples showed that 30% of the infections are caused by fungi (100% were Candida albicans), 47% by Gram negative bacteria, and 23% by Gram positive bacteria. The results of MIC assays showed that the plant extract and the antifungal drug do not seem to have fungicidal effects on the isolates of C. albicans tested. The ability of C. albicans isolates for adhesion to the epithelial cells was detected by the calculation of the number of adherent C. albicans cells under light microscope. The activity of vasicin and gallic acid appeared to be approximately equal on the number of C. albicans adherent on epithelial cells. Vasicin concentration activity used in mg/ ml was higher than that used in µg/ ml, with less numbers of C. albicans adhered on epithelial cell. However, treatment with fluconazole showed that more than half of the number of C. albicans were non-adherent on epithelial cells when added to the suspension, in contrast to the control (C. albicans without the extracts or antifungal drug).
An effective two-body density operator for point nucleon system
folded with the tenser force correlations( TC's), is produced and used
to derive an explicit form for ground state two-body charge density
distributions (2BCDD's) applicable for 25Mg, 27Al and 29Si nuclei. It is
found that the inclusion of the two-body TC's has the feature of
increasing the central part of the 2BCDD's significantly and reducing
the tail part of them slightly, i.e. it tends to increase the probability of
transferring the protons from the surface of the nucleus towards its
centeral region and consequently makes the nucleus to be more rigid
than the case when there is no TC's and also leads to decrease the
1/ 2
r 2 of the nucleu
An effective two-body density operator for point nucleon system folded with the
tenser force correlations ( TC's), is produced and used to derive an explicit form for
ground state two-body charge density distributions (2BCDD's) applicable for
19F,22Ne and 26Mg nuclei. It is found that the inclusion of the two-body TC's has the
feature of increasing the central part of the 2BCDD's significantly and reducing the
tail part of them slightly, i.e. it tends to increase the probability of transferring the
protons from the surface of the nucleus towards its centeral region and consequently
makes the nucleus to be more rigid than the case when there is no TC's and also
leads to decrease the
1/ 2
2 r of the nucleus. I
The elastic magnetic electron scattering form factors and the magnetic dipole moments have been studied for the ground state of 19C (halo) (JπT= 1/2+ 7/2) nucleus carried out using psd-shell Millener-Kurath (PSDMK) interactions. The single-particle wave functions of harmonic-oscillator (HO) potential are used with two different oscillator parameters bcore and bhalo. According to this interaction, the core nucleons of 18C nucleus are assumed to move in the model space of spd. The outer halo (1-neutron) in 19C is assumed to move in the pure 2s1/2 orbit. The elastic magnetic electron scattering of the stable 13C and exotic 19C nuclei are investigated through Plane Wave Born Approximation (PWBA). It is found that the difference between the
... Show MoreThe organization uses many techniques and methods to ensure that they will succeed and adapted with velocity change in the internal and external environment by decision taking, especially strategic decisions.
Strategic decisions are very important for organization success because it can predict the future and deal with uncertainty, in this circumstances they need accurate and comprehensive information to make effective strategic decision.
To achieve that purpose it must owned successful Strategic Information System ( SIS ) and determined the critical success factors for this system ,which can assisted the worker to focus on the important activities to develop it.
... Show MoreIn gene regulation, transcription factors (TFs) play a key function. It transmits genetic information from DNA to messenger RNA during the process of DNA transcription. During this step, the transcription factor binds to a segment of the DNA sequence known as Transcription Factor Binding Sites (TFBS). The goal of this study is to build a model that predicts whether or not a DNA binding site attaches to a certain transcription factor (TF). TFs are regulatory molecules that bind to particular sequence motifs in the gene to induce or restrict targeted gene transcription. Two classification methods will be used, which are support vector machine (SVM) and kernel logistic regression (KLR). Moreover, the KLR algorithm depends on another regress
... Show MoreThe main goal of this research is to determine the impact of some variables that we believe that they are important to cause renal failuredisease by using logistic regression approach.The study includes eight explanatory variables and the response variable represented by (Infected,uninfected).The statistical program SPSS is used to proform the required calculations
The elastic magnetic electron scattering form factors and the magnetic dipole moments have been studied for the ground state of 19C (halo) (JπT= 1/2+ 7/2) nucleus carried out using psd-shell Millener-Kurath (PSDMK) interactions. The single-particle wave functions of harmonic-oscillator (HO) potential are used with two different oscillator parameters bcore and bhalo. According to this interaction, the core nucleons of 18C nucleus are assumed to move in the model space of spd. The outer halo (1-neutron) in 19C is assumed to move in the pure 2s1/2 orbit. The elastic magnetic electron scattering of the stable 13C and exotic 19C nuclei are investigated through Plane Wave Born Approximation (PWBA). It is found that the difference between the
... Show MoreThis research paper studies the use of an environmentally and not expensive method to degrade Orange G dye (OG) from the aqueous solution, where the extract of ficus leaves has been used to fabricate the green bimetallic iron/copper nanoparticles (G-Fe/Cu-NPs). The fabricated G‑Fe/Cu-NPs were characterized utilizing scanning electron microscopy, BET, atomic force microscopy, energy dispersive spectroscopy, Fourier-transform infrared spectroscopy and zeta potential. The rounded and shaped as like spherical nanoparticles were found for G-Fe/Cu‑NPs with the size ranged 32-59 nm and the surface area was 4.452 m2/g. Then the resultant nanoparticles were utilized as a Fenton-like oxidation catalyst. The degradation efficiency of
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