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Assessment of Levels of Metabolic Hormones and Lipid Profile in Growth Hormone Deficient Patients
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Abstract

The current study aims to evaluate levels of metabolic hormones and lipid profile in a sample of growth hormone (GH) deficient patients. Seventy five GH deficient patients and twenty healthy subjects used as control group have been participated in this study during their attendance to the National Diabetic Center for Treatment and Research/Al-Mustansiriya University. The studied subjects’ ages were with a range (3-15 years). Blood samples were collected from the studied subjects to determine levels of basal GH, GH2 and GH3 after 1 hr and 1/30 hr provocation with clonidine, respectively; insulin like growth factor (IGF-1); levels of metabolic hormones [thyroid profile: triiodothyronine (T3), thyroxin (T4), and thyroid stimulating hormone (TSH)]; and lipid profile [cholesterol, triglyceride, high density lipoprotein (HDL), low density lipoprotein (LDL) and very low density lipoprotein (VLDL)].

The findings of the anthropometric measurements of the studied groups revealed that a non-significant (P>0.05) difference was found in the weight between the patients and the control, while the mean of height in the patients was significantly (P<0.05) lower than its value in the control. Mean of BMI detected a non-significant (P>0.05) difference between the patients and the control. While mean of BMI percentile and mean of BMI Z-score revealed significant (P<0.05) decrease in the patients compared to their values in the control.

The results showed that non-significant (P>0.05) difference was found in level of basal GH between the patients and the control, while a high significant (P<0.01) decrease was found in levels of GH2 and GH3 in the patients group compared to the control group. Level of IGF-1 showed a significant (P<0.05) decrease in the patients compared to the control.

The results of metabolic hormones revealed a non-significant (P>0.05) difference in serum T3 between the patients and the control, while a high significant (P<0.01) decrease was found in serum T4 in the patients compared to the control.  A non-significant (P>0.05) difference was found in serum TSH between the patients and the control. The data of serum cortisol showed a significant (P<0.05) increase in the patients compared to the control.

The results of lipid profile showed a non-significant (P>0.05) difference in serum cholesterol between the patients and the control, while triglyceride showed a significant (P<0.05) increase in the patients compared to the control. A non-significant (P>0.05) difference was found in serum HDL between the patients and the control, while a significant (P<0.05) increase was found in levels of LDL and VLDL in the patients compared to the control.

It can be concluded from the present study that diagnosis of GHD cannot be done at the basal serum of GH.  A high level of GH was detected after 1 hr. provocation with clonidine compared with its value after 1/30 hr. provocation. The IGF-1 is an appropriate parameter to expect GHD in children and adolescences whom GHD was detected by GH stimulation testing. Low GH secretion is associated with high level of cortisol resulting in GHD.  Patients with GHD displayed a tendency towards lipids disturbances.

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Publication Date
Tue Aug 15 2023
Journal Name
Al-academy
The effectiveness of artificial intelligence in contemporary digital graphic design
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In our world, technological development has become inherent in all walks of life and is characterized by its speed in performance and uses. This development required the emergence of new technologies that represent a future revolution for a fourth industrial revolution in various fields, which contributed to finding many alternatives and innovative technical solutions that shortened time and space in terms of making Machines are smarter, more accurate, and faster in accomplishing the tasks intended for them, and we find the emergence of what is called artificial intelligence (artificial intelligence), which is the technology of the future, which is one of the most important outputs of the fourth industrial revolution, and artificial inte

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Publication Date
Sat Apr 15 2023
Journal Name
Iraqi Journal Of Science
Sorption efficiency of kaolinte in removal Cd from aqueous solutions
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Because of the contaminants represented by heavy metals in the aquatic
environment have an adverse effects need to be addressed, therefore, a laboratory
simulation was conducted on Cd using kaolinite that collected from Ga’ara Formation
as considered as a natural sorbent material that can be used to remove heavy metals
from aqueous environments. Mineralogical study was conducted on kaolinite using
X-Ray diffraction (XRD), Scanning Electron Microscope (ESM) and Energy-
Dispersive X-ray Spectroscopy (EDS) for the purpose of investigating the microtexture.
It was found that kaolinite has pure phase of very fine grains with a very little
quantity of quartz and has a number of active sites for adsorption. Chemical an

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Publication Date
Wed Feb 20 2019
Journal Name
Political Sciences Journal
The American vision of the Non-governmental Organizations in Iraq
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The American vision of the Non-governmental Organizations in Iraq the topic area of that’s paper dealing with Civil Society as concept and practice, its already consider as Western concept and associated with liberalism and political development, they are many definitions of its but most significantly is all organizations, agencies, trade unions and non-governmental institutions, that’s agencies were established after 2003 and received funds from United States and UN development agencies. The non- governments organizations played a significant role as support and develop many cultural, healthy, educational, and social projects, also that’s organizations try to reduction the effects of terrorists actions especially after ISI

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Publication Date
Sat Feb 01 2020
Journal Name
Journal Of Economics And Administrative Sciences
Reflection of the service encounter environment in enhancing customer satisfaction
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Because of the fierce competition between service organizations on the one hand and the increasing demands of customers on the other. Therefore, these organizations sought to distinguish their service by taking care of all aspects. One of these important aspects is the service encounter environment and its reflection on customer emotions, so we choose the current research to clarify the importance and impact on customer satisfaction, the problem of research is how the interest of Iraqi restaurants in the service encounter environment and how to care about its elements and whether this interest is sufficient to reflect the satisfaction of the customer. the goal of the current research was to clarify how much the application of the

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Crossref
Publication Date
Mon Feb 04 2019
Journal Name
Iraqi Journal Of Physics
Experimental investigation of dusty plasma characteristics in AC discharge system
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In the present work, the effect of size of zinc dust particles on
AC argon discharge characteristics are investigated
experimentally. The plasma characteristics are determined by
using optical emission spectroscopy (OES) techniques. The
results illustrated that the electron temperature (Te) in the present
and absent of Zinc dust particle is reduced with increasing of
pressure. The electron temperature decreases with increasing of
Zinc dust size. Excitation temperature Tex is reduces with
increasing of Ar pressure in present and absent of zinc dust
particles. The present of Zinc dust reduce the Tex of Ar in both
Zinc dust size. The electron density increasing in the present and
absent of both zinc dust siz

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Crossref
Publication Date
Mon Feb 04 2019
Journal Name
Journal Of The College Of Education For Women
Mystic love poems in the poetry of Atika Al-Khazraji
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We deal with this essay about religious mystic poetry of Atika Al-
Khazraji. We think she imitates Rabia Al-Adawiyya. We do not deny that our
poetess lived in a conservative society although she lives in reality a liberal
life, so she tries to satisfy her society. In fact these mystic poems are pure
love. Poems in men.
This double standard behavior is quite clear in women’s poems in the
Arab world of this era.

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Publication Date
Sun Mar 06 2011
Journal Name
Baghdad Science Journal
Epidemiological Study of Viral Hepatitis/ Chibayish Marsh Reality in Iraq
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Total of 170 samples were collected from Al-Chibayish Marsh reality in Dhi-Qar governorate southern of Iraq to study the epidemology of viral hepatitis in these areas and to detect the type of hepatitis viruses which include A ,B,C,D .The percentage of hepatitis A was 1.17% and most of them below age of ?10 (66.6%) while infection with hepatitis B account 5.29% and includes all age groups. There was no detected cases of hepatitis C,D. The laboratory study showed that the incidence of hepatitis B higher in male (4.11%) compared to female ( 2.35%)

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Crossref
Publication Date
Thu Sep 12 2019
Journal Name
Al-kindy College Medical Journal
The role of prophylactic antibiotics in nasal packing for epistaxis
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Background: This study is to evaluate the necessity of prescribing prophylactic antibiotics for nasal packing in spontaneous epistaxis. There are few published papers of infective complications in such patients.

Methods: This prospective study analysed 149 consecutive patients admitted to AL-Kindy teaching hospital with spontaneous, epistaxis, who underwent nasal packing  over 2 years period . in the first  year, 78 patients received prophylactic antibiotics , In the second  year 71 patients were not given prophylatic antibiotics.  Exclusion criteria included antibiotics prescribed for unrelated  pathology and post-operative epistaxis. Signs and symptoms of acute otitis m

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Crossref
Publication Date
Mon Oct 01 2018
Journal Name
Journal Of Engineering
Experimental Study of Hybrid Solar Air Conditioning System in Iraq
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In this paper, an experimental study of the thermal performance for hybrid solar air conditioning system was carried out, to investigate system suitability for the hot climate in Iraq. The system consists of vapor compression unit combined with evacuated tube solar collector and liquid storage tank. A three-way valve was installed after the compressor to control the direction flow of the refrigerant, either to the storage tank or directly to the condenser. The performance parameters were collected by data logger to display and record in the computer by using LabVIEW software. The results show that the average coefficient of performance of hybrid solar air conditioning system (R=1) was about 2.42 to 2.77 and the average p

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Publication Date
Sun Aug 13 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Characteristic Behavior of Ion Acoustic Wave in A dusty Plasma
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In this research, we make an attempt to derive theoretically 1-D linear dispersion relation of ion-acoustic waves in uniform unmagnetized dusty plasma valid in the long wavelength limits. This equation matched previously special equation of acoustic modes of a general form in magnetized dusty plasma.  Depending on previously mentioned experimental data, we numerically consider various parameters that affect the properties of these waves in   dusty plasma. The study has shown that the presence of dust grains is to modify the properties of ion acoustic waves and affect the behavior of the plasma in which they are immersed.  

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