Plants and their extracts preparations have been used as medicines against infectious diseases. In present work, Cassia senna (leaves), Piper nigrum (fruits) were extracted with different organic solvents to investigate their antifungal activities in vitro. However, the effective of plant extracts against some pathologic fungi (Tricophyton rubrum, T. tonsurans, T. violaceum, Microsporum audouinii, M. canis and M. gypseum) were evaluated at concentrations ranged between (0.005–5%) using agar diffusion methods and compared with standard antifungal drug (Clotrimazole). Results showed that methanol extract of C. senna and ethanol extract of P. nigrum displayed excellent inhibition on dermatophytes compared with standard antifungal drug, the MFC value for C. senna extract against dermatophyte isolates was (0.5%) except T. rubrum and M. canis (0.1%), the MIC was (0.05%). MFC value for P. nigrum extract against T. violaceum, M. audouinii and M. gypseum was (0.1%) while for M. canis was (0.05%), T. rubrum and T. tonsurans was (0.01%) and the MIC value was (0.005%). But MFC value for clotrimazole was (0.5%) and the MIC value was (0.1%). The yield of active compounds in C. senna and P. nigrum were (3, 6.7%) respectively. Also, the chemical compositions of these extracts were analyzed by FLC (Fast Liquid Chromatography) the result shows that the main components in C. senna were phenols, alkaloids and glycosides, while in P. nigrum were phenols, alkaloids and there was no terpens.
Adversity and psychosocial stress are involved in aging through the following pathways. psychological stress enhances the nerve system to secrete endocrine mediators (hormones). Mitochondrial respiration mediates energy production stimulated by binding to these hormones to their receptors. Energy produced by mitochondria accelerates metabolism and, in its turn, leads to increases in reactive oxygen species (ROS) of free radicals. Cellular stress and accumulation of damage can result from an excess of ROS. Accumulation of damage comprises damages in telomeric and nontelomeric DNA, in addition to mitochondrial DNA. Mitochondrial DNA damage plays an important role in increasing the pathway of p53/p21. The expression of the PGC-1α gene
... Show MoreThe pollution producing from textile industries effluents is growing since the years, due to at discharged lots of it in water without treatment. The resulting effluent is colourful, highly toxic, and poses a significant environmental hazard. This problem can be solved by using enzymic biological treatment, where the Congo red dye was used with concentrations (100,200,300,500) mg /L, pH values (3,4,5,6,7,8), and variable temperatures (25,35,45)°C, the best removal of Congo red (CR) dye under optimum conditions for degradation was at concentration of 100 mg/L, at (pH 6, 25 °C) with efficiency of 99.85 % using the peroxidase enzyme extracted from red radish plant, while the removal percentage decreased when increase dye concentration
... Show MoreAl-Rustamiyah plant is the oldest and biggest sewage treatment plant in Iraq; it locates in the south of Baghdad city. The plant suffers from serious problems associated with overflow and low capacity. The present work aims to upgrade the heart of biological treatment process through suggesting the use of membrane bioreactor; (MBR). In this work, fouling of membrane during sewage treatment has been analyzed experimentally and theoretically by fouling mechanisms. Aeration has been applied in order to control fouling through producing effective diameters of air bubbles close to the membrane walls. Effect of air flow rate on flux decline was investigated. Hermia's models were used to investigate the fouling mechanisms. The results showed th
... Show MoreThis study was conducted to describe a protocol for the callus establishing culture of Lavandula angustifolia plant and estimating their content of volatile oil. The quantity of volatile oil callus tissues was compared with that of leaves production. Callus was induced from leaf explants on Murashige and Skoog medium (MS) supplemented with Naphthalene acetic acid (NAA) and Benzyl adenine (BA) in different concentrations. Maximum callus fresh weight was obtained in the combination of 10 mg/L BA and 3 mg/L NAA which reached 18 g after four weeks. The results of this work showed that the quantity of volatile oil from the highest fresh weight callus was 6 ml compared with quantity of 18g of leaves which gave 0.5 ml. Volatile o
... Show MoreAntibiotic resistance is the major growing threat facing the pharmacological treatment of bacterial infections. Therefore, bioprospecting the medicinal plants could provide potential sources for antimicrobial agents. Mimusops, the biggest and widely distributed plant genus of family Sapotaceae, is used in traditional medicines due to its promising pharmacological activities. This study was conducted to elucidate the antimicrobial effect of three unexplored Mimusops spp. (M. kummel, M. laurifolia and M. zeyheri). Furthermore, the mechanisms underlying such antibacterial activity were studied. The Mimusops leaf extracts revealed significant antibacterial activities against the five tested bacter
... Show MoreActinomycetes are free, spore-forming, high (G+C) ratio (>55%) saprophytic microorganisms that are widely distributed in most soils, colonize plants, and are prevalent in water. This is frequently accompanied by the production of filament airborne mycelium. Actinomycetes are well-known microcolonies for creating antibiotics and other critical bioactive components that are beneficial to humans. Approximately 70% to 80% of commercially available medications and antiviral active compounds have been synthesized so far. Secondary metabolites produced by microbes have the potential to be used in a variety of sectors, including antimicrobial agents, enzyme technology, pigment manufacture, antitumor agents against cancer cells, and toxin pr
... Show MoreLead has toxic effects on reproduction of both male and female. It can cause decreased sex drive , infertility and abnormal menstrual cycle in women. This study was designed to evaluate the effect of exposure to lead in batteries female workers on sex hormones level in the serum.Thirty nine (39) female workers (volunteers) in Iraqi Batteries Manufacturing Plants, Al-Waziriya / Baghdad were participated in this study. They are classified into 3 groups, first group included fourteen (14) female that have been employed for 1-7 years , second group included thirteen (13) female that have been employed for 8-14 years , third grou
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