This study includes 15 male healthy and 30 male patients diagnosed with prostate
cancer inciude (18 cases in stages I & II and 12 cases in III – stage). All the patients
were suffered from urinary tract infection ( UTI) . The mean age is (57.33± 5.02)
years range ( 45-63) years, as cases and controls Patients with prostate cancer were
treated admits an Educational Baghdad Hospital, and Central Public Health
Laboratory and Radiation and Nuclear Medicine Hospital in Baghdad, during
period 1/6/2008 to 1/12/2010 are included in this study. The markers Prostatespecific
antigen (CA PSA), Interleukins ( IL -1 , IL-2, IL-3, IL-5) and
Immunoglobulins ( IgG, IgM, IgE) are estimated by using ELISA method. The
Clean-Catch midstream urine of the patients were collected, and cultured on blood
agar and MacConky agar to isolation of the pathogenic bacteria causes and
associated with prostate cancer. The isolated bacteria were identified according to
morphological and using biochemical tests.
The aim of this study is to fined out changes in some immune markers in prostate
cancer patients and if any correlation exists between the tumor marker in patients
serum pre and post-operation, and the bacterial pathogens of the UTI and its
correlation with prostate cancer risk.
The results show , a significant difference in CAPSA levels between healthy
control and prostate cancer patients ( stages I , II , III ) pre-operation ( P> 0.05 ),
while no appear significant difference between healthy and patients post-operation ,
The comparison between prostate cancer pre and post-operation was showed a
significant difference ( t=7.042,P > 0.05 ) with positive correlation. However ,
statistical analysis shows a significant difference in interleukins ( IL–1 , IL–2 , IL
-3 , IL-5 ) between healthy and prostate cancer patients pre-operation, whereas no
significant difference between them in post-operation , only IL-5 , also is increased
significantly (P<0.05 ) and positive correlations in interleukins levels at prostate
cancer patients pre and post-operation. The results show a significant difference in
immunoglobulins (IgG, IgE, IgM ) between healthy control compared with prostate
cancer patients pre-operation, but no significant difference post-operation. By
comparing between prostate cancer pre and post-operation a significant
correlation(P>0.05) but only IgM has no correlation( r=0.149,P=0. 432) were
appeared.
In this study 30(100%) patients are shown to be urine culture positive. Were
inciude E. coli with frequency rate of 43.33%, Pseudomonas aerginosa (16.66 %),
Klebsiella spp. (16.66%), Enterobacter spp. (10 %), , Acinetobacter spp. (3.33%),
Serratia spp. (3.33%), and Staphylococci spp. (6.66%).
Background: Laparoscopic colectomy is performed in an increasing number of institutions as a minimally invasive treatment for benign and malignant large bowel disease. Laparoscopic rectal surgery enables more accurate visualization of the anatomical structure in the pelvic cavity for selected patients with tumors in the middle and low rectum.
Objectives: To determine the early outcome of patient who underwent laparoscopic low anterior resection using radial reload stapler.
Patients and methods: This is a prospective study of 8 patients with low or mid rectal cancer who underwent a laparoscopic low anterior resection between January 2017 till June 2017 at Saint Raphael hospital.
Results: Eight patients underwent elective laparosc
The cytotoxic effect of different concentrations of Crude extracts of Solanum melongena , Curcuma longa and Daucus carota on mice mammary adenocarcinoma cell line was studied . The concentrations used were 62.5 125 , 250, 500 Microgram/militer for 24,48 and 72 hour . These exracts were prepared by using alcoholic and hot water methods . The preliminary chemical tests revealed acidic pH of all extracts. The results showed a clear toxic effect of all extracts in a time and dose –dependent manner . The Curcuma longa had the highest effect on adenocarcinoma 94.61% , followed by Solanum melonga( 93.20%) and the lowest effect was by Da
... Show MoreBackground: The anticancer impact of Epigallocatechin gallate (EGCG) the highly active polyphenol of green tea was abundantly studied. Though, the exact mechanism of its cytotoxicity is still under investigation. Objectives: Hence, the current study designed to investigate the molecular target of EGCG in HepG2 cells on thirteen autophagy- and/or apoptosis- related genes. Methods: The apoptosis detection analyses such as flow cytometry and dual apoptosis assay were used. The genes expression profile was explored by the real-time quantitative-PCR. Results: EGCG increases G0/G1 cell cycle arrest and the real-time apoptosis markers proteins leading to stimulate apoptos
... Show MoreThe reaction of LAs-Cl8 : [ (2,2- (1-(3,4-bis(carboxylicdichloromethoxy)-5-oxo-2,5- dihydrofuran-2-yl)ethane – 1,2-diyl)bis(2,2-dichloroacetic acid)]with sodium azide in ethanol with drops of distilled water has been investigated . The new product L-AZ :(3Z ,5Z,8Z)-2- azido-8-[azido(3Z,5Z)-2-azido-2,6-bis(azidocarbonyl)-8,9-dihydro-2H-1,7-dioxa-3,4,5- triazonine-9-yl]methyl]-9-[(1-azido-1-hydroxy)methyl]-2H-1,7-dioxa-3,4,5-triazonine – 2,6 – dicarbonylazide was isolated and characterized by elemental analysis (C.H.N) , 1H-NMR , Mass spectrum and Fourier transform infrared spectrophotometer (FT-IR) . The reaction of the L-AZ withM+n: [ ( VO(II) , Cr(III) ,Mn(II) , Co(II) , Ni(II) , Cu(II) , Zn(II) , Cd(II) and Hg(II)] has been i
... Show MoreMeasurement of 238U, 233Th and 40K concentrations in soil samples collected from Ziggurat of Dur-Kurigalzu west region of Baghdad, have been evaluated, using high purity germanium detector. The activity concentrations of 238U, 233Th and 40K varied from 16.040 to 26.620 , 14.510 to 31.480 , and 153.820 to 266.320 with average values of 20.604±2.9 , 24.534±3.3 , 212.22±25.1 , respectively. The importance of these measurements lies in the estimation of radiation risk, radium equivalent, absorbed dose, annual effective dose, risk indices, gamma index, and cancer risk. The average value of the absorbed dose ranged from 33.187 outdoors to 63.111 indoo
... Show MoreObjective(s): To determine the impact of instructional intervention program upon psychological health status for
women who undergo chemotherapy after mastectomy
Methodology: The sample consisted of (100) women, (50) considered as study group, and another (50) the control
group. A pre test was done for both groups (study and control), and then the study samples were exposed to an
instructional intervention and three-dimensional post tests and the length of time between each test 21 days in
the Institute and Hospital of Radiation and Nuclear Medicine. The questionnaire composed of three parts, first,
demographic information; include (age, educational level, type of family, occupation, marital status, and adequacy
of mo
In this paper two modifications on Kuznetsov model namely on growth rate law and fractional cell kill term are given. Laplace Adomian decomposition method is used to get the solution (volume of the tumor) as a function of time .Stability analysis is applied. For lung cancer the tumor will continue in growing in spite of the treatment.
An increasing interest is emerging in identifying natural products to overcome drug resistance in cancer patients. In this context, the present study was conducted to investigate the cytotoxic effects of neem plant (Azadirachta indica) oil in three different biological models (breast cancer cell lines, Allium cepa root tip, and mice vital organs). The cytotoxic potential of the neem oil was evaluated with two human cell lines (MCF7 and MDA-MB231) and an Allum cepa root tip bioassay. Histopathological analysis was conducted on the neem oil-treated and untreated control mice. The results revealed an anti-proliferative effect for neem oil on both estrogen receptor-positive (MCF7) and estrogen receptor-negative (MDA-MB231) breast cancer cell li
... Show MoreThis study includes the preparation of the ferrite nanoparticles CuxCe0.3-XNi0.7Fe2O4 (where: x = 0, 0.05, 0.1, 0.15, 0.2, 0.25, 0.3) using the sol-gel (auto combustion) method, and citric acid was used as a fuel for combustion. The results of the tests conducted by X-ray diffraction (XRD), emitting-field scanning electron microscopy (FE-SEM), energy-dispersive X-ray analyzer (EDX), and Vibration Sample Magnetic Device (VSM) showed that the compound has a face-centered cubic structure, and the lattice constant is increased with increasing Cu ion. On the other hand, the compound has apparent porosity and spherical particles, and t
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