The study area is located to the south of Iraq at Al-Shanafiya town, south west of Iraq. Groundwater is the main source for crops irrigation, household uses and livestock drinking. To determine the relative age of groundwater by measuring the tritium concentration in groundwater, four wells and four springs water samples were taken. Found that the mean tritium concentration in springs samples is 4.125 TU where in wells samples is 2 TU. Using Clark and Firtz (1997) classification found that the relative age is amix of sub modern and modern water. Through modern study was performed by Al-Paruany (2013) found that the tritium concentration in rainfall in Al-Diwaniyah Meteoric Station has reached the natural level (approximately 5TU). Through this , recent study can be applied by Mazor (2004) to determine the age of more accurate, found that the spring water effective age may be not more than 5 years. Eighteen representative groundwater samples were collected from wells and springs, were subjected to chemical analysis to measurement the major ions concentration. The water samples are alkaline in nature, they have high TDS and EC. Piper classification was applied and found that the groundwater samples are confined in the fields 2, 3 and 5 (Na-Cl, Ca-Mg-Cl and Ca-Cl water types). Chadha's diagram was applied for better understanding, water samples are confined in the fields 6, 4 and 7, nearly identical with Piper classification. The groundwater is unsuitable for human drinking, building and for all industries. But it is suitable for domestic uses and live stocks. The suitability of groundwater for irrigation, the samples (S1, S2, W1, W8, and W13) are fair water while the other samples were classified poor water.
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Background: Excision repair cross-complementing group 2 gene (ERCC2) polymorphisms have been linked as being a risk factor for colorectal cancer (CRC) emergence. However, data from several studies are contradictory. To validate genetic biomarkers of the CRC; the impact of the following ERCC2 polymorphism (rs1799793 and rs238406) was examined on CRC susceptibility among sample of Iraqi population. Methods: A total of 126 subjects were enrolled in this case control study; 78 CRC patients and 48 apparently healthy individuals who are age, gender, smoking status and BMI matched. Polymerase chain reaction (PCR) was used for genotyping, followed by sequencing then the association between genetic polymorphisms and CRC risk was investigate
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The pharmacophore 2-aminothiazole has an interesting role in pharmaceutical chemistry as this led to the synthesis of many types of compounds with diverse biological activity. Schiff base derivatives at the same time contribute to drug evolution importantly. In this review, the Schiff base derivatives of 2-aminothiazole formed and some of their metal complexes are being focused on, and the antimicrobial and anticancer activity of them is being illustrated.
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The pharmacophore 2-aminothiazole has an interesting role in pharmaceutical chemistry as this led to the synthesis of many types of compounds with diverse biological activity. Schiff base derivatives at the same time contribute to drug evolution importantly. In this review, the Schiff base derivatives of 2-aminothiazole formed and some of their metal complexes are being focused on, and the antimicrobial and anticancer activity of them is being illustrated.
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Flurbiprofen (FLB) is chemically 2-(3- fluoro-4-phenyl phenyl) propanoic acid. It is a nonsteroidal anti-inflammatory drug (NSAID) used in the treatment of rheumatoid arthritis and osteoarthritis. Oral administration of this drug is associated with severe gastrointestinal side effects like ulceration and gastrointestinal bleeding. The solution to this problem lies in the fact that topically applied NSAIDs are safer than orally. This study aims to prepare different topical semisolid formulation of FLB as cream base (o/w), (w/o) and gel base using different gel-forming agents in different concentrations. Comparing characterization properties in addition to release and diffusion study for all the prepared formulas to select the best on
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Objective: Econazole nitrate (ECZ) is one of the triazole antifungal drugs with poor aqueous solubility and dissolution rate; there is a need for enhancement of solubility. Therefore; inclusion complexation with β cyclodextrin (βCD) was performed. Methods: In this study kneading method and co-evaporation method of preparation of inclusion complex between βCD and ECZ using two molar ratios of βCD. The solubility of these complexes in isotonic saline solution and distilled water was studied. Complexes prepared by kneading method were used for the preparation of different ophthalmic gel formulas using carbomer (CB) and sodium carboxymethylcellulose (sod CMC) as a gelling agent. The release profile and the rheological behaviour of the gel w
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