With the aim of developing potential antimicrobials, a series of new 5-fluoroisatin derivatives incorporated with different secondary amines (piperidine, morpholine, pyrrolidine, dimethylamine, and diphenylamine) for monomer, and (piperazine) in case of dimer Mannich bases, separately in presence of formaldehyde to obtain Mannich bases of 5-fluoroisatin derivatives, which then each Mannich derivatives reacts with phenylhydrazine to form Schiff bases as final products. The resulting compounds were characterized by two spectroscopic analyses; (Fourier- transform infrared) FT-IR and proton nuclear magnetic resonance spectroscopy (¹H-NMR). In addition, the in vitro antibacterial and antifungal activities were tested against some human pathogen

The aim of present study was to develop solid and liquid  self-microemulsifying drug  delivery system of poorly water soluble drug mebendazole using Aerosil 200 as solid carrier.  Microemulsions are clear, stable, isotropic liquid mixtures of oil, water and surfactant, frequently in combination with a co-surfactant having droplet size range usually in the range of 20-250 nm. Oleic acid, tween 80 and polypropylene glycol were selected as oil, surfactant and co-surfactant respectively and for preparation of stable SMEDDS, micro emulsion region was identified by constructing pseudo ternary phase diagram containing different proportion of surfactant: co-surfactant (1:1, 2:1 and 3:1), oil and water. In brief S/ CoS mix means su

Objective: Carbamazepine is typically used for the treatment of seizure disorders and neuropathic pain. One of the major problems with this drug is its low solubility in water; therefore the objective of this study was to enhance the solubility of carbamazepine by complexation with cyclodextrin to be formulated as effervescent and dispersible granules.Methods: Solvent evaporation method was used to prepare, binary (Carbamazepine/β-cyclodextrin) complex and ternary (Carbamazepine/β-cyclodextrin/hydroxypropyl methyl cellulose (HPMC E5). The more soluble complex will be further formulated as unit dose effervescent and dispersible granules. The complexes were evaluated for their solubility, drug content, percentage practical yield and

Praise be to God, Lord of the worlds, and prayers and peace be upon the master of the messengers, his family and all his companions. And after:
      This research talks about a topic that has taken a great deal of attention and controversy among many Arabic language scholars, which is the subject of poetic necessity, but it does not talk about the necessity in general, but one of the scholars and writers who had stances and references to this issue was chosen in many places from their books. Abu Al-Ala 'Al-Maari was among the scholars who dealt with this issue on numerous occasions and occasions, and this was evident in his books.

    We chose this topic to see how Abu Al-Ala

The Islamic thought still suffers from the problems posed by Western thought in the modern era, especially after the establishment of the modern Arab state, and replacing the intellectual reference that prevailed at that time, which is represented by Islamic thought with another intellectual reference represented by Western thought. Since then, thinkers and innovators and reformers and intellectuals of the Islamists, Are trying to get out of these many problems and multiple, after imposing the nature of that thought and those references with all their consequences, and one of these problems that is still Islamic thought suffers, the bilateral problem that some academics have raisedThe title of the symposium failed The Islamic thought and

Through the title of the research, it is clear that beliefs in different religions are considered the important principles that distinguish religions, sects, and sects from each other, and belief is the important foundation and pillar on which the individual and society is based, because God Almighty called for reflection and reflection to choose his peaceful belief away from blind imitation. It is (belief in the existence of God, and His unification - and glorifying His attributes - and belief in the prophets in general, and belief in the angels in general, and in the revealed books in general).

Modern linguistic theories have given the researchers some real opportunities to find out important linguistic phenomena that

تعد فرقة المعتزلة من الفرق الإسلامية الكبيرة التي شغلت حيزاً كبيراً في التاريخ الإسلامي, فقد ظهرت المعتزلة كفرقة ذات نسق عقيدي مميز الى الوجود في العصر الأموي , ولكنها شغلت الفكر الإسلامي في العصر العباسي عندما بلغت أوج قوتها ردحاً طويلاً من الزمن .

Praise be to God, Lord of the worlds, and prayers and peace be upon our master Muhammad and upon his family and companions as a whole.
    The topic of attention was drawn to the attention of the speakers, as it made me ponder it carefully, and my goal in that is to know the reason for the interest of the speakers and their care for it, and to clarify from their books the purpose of making this topic one of the advanced investigations with them.

     The idea of ​​writing a paper on the subject of consideration was not absent from my thinking, because I saw the attention of speakers on this issue, as they made it one of the first issues that they deal with studying in their work

Al-Jahiz was an aesthetic philosopher, and the concept of beauty for Al-Jahiz depended on objectivity and focus on the idea of moderation