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A review of recent developments in pharmaceutical chemistry on biological evolution of tetrazole derivatives

This review sums up the developments in the biological activity of tetrazole active derivatives in recent days. Some of the deliberated derivatives of tetrazole are at present actively scientifically studied; some of them have biological activity that enables them to be studied further in the future as a drug for various biological activities. This review seeks to offer a comprehensive analysis of the efficacy and clinical advantage of biological activity for tetrazole derivatives.

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Publication Date
Fri Jan 01 2016
Journal Name
International Journal Of Surgery Case Reports
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Publication Date
Thu Jan 13 2022
Journal Name
Iraqi Journal Of Science
Facies Analysis of The Siliciclastic-calciturbidites, Gercus Formation In Dokan Area, Ne-Iraq; New Insight On Deposition Enviroment And Basin Evolution

Sedimentologic and facies evidences reveal a marine environment for the Gercus Formation. Facies analysis and associated sedimentary structures including graded beddings decide turbidity origin of the rocks. Marine environment is supported by the identifying glauconite and fossils types reported for the first time.
The formation composed of seven lithotypes; shale/claystone, mudstone, sandstone, carbonate, conglomerate, breccias and debris flow, which are arranged in repeated cycles of mixed siliciclastic-carbonate turbidites in a range of gravity-flow regime. The Gercus successions are grouped into four facies associations confirming marine depositional systems, these are (from bottom to top); slump siliciclastic-calciturbidites (dol

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Publication Date
Sun Apr 01 2018
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Laparoscopic colorectal surgery in Baghdad teaching hospital A review of 12 patients

Background: colonic resections by laparoscopy are being performed with increasing frequency worldwide.
Objective: The aim of this study is to evaluate our experience in the laparoscopic management of colorectal disease and to compare our results with other institutes.
Patients and Methods: This is a prospective study conducted during the period from 1st of January 2017 till the 15th of November 2017, 12 patients underwent laparoscopic colectomy in in Baghdad Teaching Hospital and followed up for 30 days postoperatively.
Results: 12 patients were included in this study, 83.3% of them were male, majority of patients (41.7%) were between 60 – 69 years, most of th

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Publication Date
Mon Feb 01 2021
Journal Name
Journal Of Engineering
The Synergic Effects of Mineral Admixtures in Ternary Blended Cement: A Review

In the last decades, using mineral admixture in concrete became very necessary to improve concrete properties and reduce CO2 emissions associated with the cement production process. Subsequently, more sustainable concrete can be obtained.  Ternary blended cement containing two different types of mineral admixture can achieve ambitious steps in this trend. In this research, the synergic effects of mineral admixtures in ternary blended cement and its effects on concrete fresh properties, strength, durability, and efficiency factors of mineral admixture in ternary blended cement, were reviewed. The main conclusion reached after reviewing many literature pieces is that the concrete with ternary blended cement

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Publication Date
Sun Sep 03 2023
Journal Name
Al-mansour Journal
Biometrics Systems Challenges in a Post-COVID-19 Pandemic World: A review

One of the most serious health disasters in recent memory is the COVID-19 epidemic. Several restriction rules have been forced to reduce the virus spreading. Masks that are properly fitted can help prevent the virus from spreading from the person wearing the mask to others. Masks alone will not protect against COVID-19; they must be used in conjunction with physical separation and avoidance of direct contact. The fast spread of this disease, as well as the growing usage of prevention methods, underscore the critical need for a shift in biometrics-based authentication schemes. Biometrics systems are affected differently depending on whether are used as one of the preventive techniques based on COVID-19 pandemic rules. This study provides an

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Publication Date
Thu Jun 01 2023
Journal Name
Baghdad Science Journal
Simultaneous Determination of Piroxicam and Codeine Phosphate Hemihydrate in a Pharmaceutical Dosage Form Using Validated HPLC Method

An easy, eclectic, precise high-Performance Liquid Chromatographic (HPLC) procedure was evolved and validated to estimate of Piroxicam and Codeine phosphate. Chromatographic demarcation was accomplished on a C18 column [Use BDS Hypersil C18, 5μ, 150 x 4.6 mm] using a mobile phase of methanol: phosphate buffer (60:40, v/v, pH=2.3), the flow rate was 1.1 mL/min, UV detection was at 214 nm. System Suitability tests (SSTs) are typically performed to assess the suitability and effectiveness of the entire chromatography system. The retention time for Piroxicam was found to be 3.95 minutes and 1.46 minutes for Codeine phosphate. The evolved method has been validated through precision, limit of quantitation, specificity,

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Publication Date
Mon Apr 01 2024
Journal Name
Chemical Engineering Research And Design
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Publication Date
Wed Jan 01 2020
Journal Name
International Journal Of Pharmaceutical Research
Spectrophotometric Evaluation of Paracetamol in Bulk and Pharmaceutical Preparations

An uncomplicated, new and sensitive spectrophotometric technique for determining paracetamol was presented in this research article. The suggested technique includes the reacting Sodium nitrite (NaNO2) with hydrochloric acid to yield nitrous acid (HO-NO) and the acid reacting with paracetamol in a hydrochloric acid medium for producing orange colored product with an extreme absorbing at 431.0 nm. There haven’t any observed interferences from the typical excipients in the formulations. The technique is efficaciously engaged for the determining paracetamol in numerous medicinal formulations. The fallouts have statistically compared with gotten results based on the official technique.

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Publication Date
Fri Nov 11 2022
Journal Name
Al-nisour Journal For Medical Sciences
Spectrophotometric determination of sulfamethoxazole in pure and pharmaceutical formulations

New, easy, simple, and fast spectral method for estimation of sulfamethoxazole (SMZ) in pure and pharmaceutical forms. The proposed method is based on the azotization of the drug compound by sodium nitrite in an acidic medium and then coupling with 2,3dimethyl phenol reagent (DMP) in a basic medium to yield an orange-coloured dye which shows λmax at 402 nm. Different affection of the optimization reaction has been completed, following the classical univariate sequence. The concentration of sulfamethoxazole about (1-15) μg. mL-1 with molar absorptivity of (14943.461) L.mol1 .cm-1 that obeyed Beer’s law. The detection and quantification limits were (0.852, 2.583) μg. mL-1 respectively, while the value of Sandell’s sensitivity (

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Publication Date
Mon May 22 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Spectrophotometric Determination of Isoptin (Verapamil Hydrochloride) in Pharmaceutical Preparations

Verapamil Hydrochloride (VH) has been determined spectrophotometrically by using Methyl Orange (MO).  In our previous researches MO was used for determination of Mexiletine Hydrochloride [1]. The method was based on complexation between (MO and VH).  After shaking and diluting the complex solution with D.W, the pH was adjusted with NaOH and HCl to pH 4. The colored complex formed between VH and the reagents were transferred into separating funnels and extracted using 4.5 ml CH2Cl2 and were shaken for (4 minutes).  The extracted organic layer was used for the preparation of the calibration curves for spectrophotometric measurements of VH at 437nm.  The blanks were carried out in exactly the same way throughout the whol

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