Since its start spreed "Severe acute respiratory syndrome coronavirus 2" was discovered in Wuhan, China.that is chargeable COVID-19, a pandemic virus, has end up a widespread fitness hassle everywhere in the global Over 2.1 million people have been affected. We analyze serum concentration of CD4 marker and CD8 marker depend in COVID-19 sufferers, and to make clear a relationship between these variables and disorder Progression and severity For those purpose, (158) sufferers with COVID-19 (showed with the aid of using polymerase chain reaction) and (22) seemingly wholesome human beings have been protected withinside the present day examine and taken into consideration as a manipulate group. All examine population (sufferers and manipulate) have been subjected to the assessment of serum awareness of CD4 marker and CD8 marker. COVID-19 sufferers displayed a huge elevation withinside the tiers of parameters protected on this examine while in comparison with wholesome controls. We additionally observed that concentration of CD4 and CD8 high in sever ( CD4 5.68 ±0.16-CD8 961.74 ±49.48 ) than critical ( CD4 4.76 ±0.14- CD8 880.19 ±52.03 )and moderate (CD43.83 ±0.09 – CD8 647.52 ±44.54 ) groups with high significant different (P≤0.01(
