Enamel White Spot Lesions (EWSLs) are a common dental condition characterized by being opaque or chalky white in appearance. In this review, an overview of the etiology, prevention, and treatment techniques for EWSLs is presented. Enamel demineralization caused by bacteria in dental plaque which releases acids upon the consumption of fermentable carbohydrates causing mineral loss is thought to be the main cause of those lesions, which could be predisposed through orthodontic treatment, poor diet, inadequate oral hygiene and certain medical conditions. So, sustaining an adequate carbohydrate consumption, proper fluoride exposure and good oral hygiene are some of the practices which aid in these lesions’ prevention. Although the success or failure of treatment of EWSLs depends on patient cooperation, depth of the lesion and lesion severity, treatment of those EWSLs should begin with the most conservative approach like remineralization and if failed then more invasive microabrasion, infiltration and maybe even restoration treatment strategies can be pursued. Further research is still needed in the prevention and treatment strategies.
