Today’s academics have a major hurdle in solving combinatorial problems in the actual world. It is nevertheless possible to use optimization techniques to find, design, and solve a genuine optimal solution to a particular problem, despite the limitations of the applied approach. A surge in interest in population-based optimization methodologies has spawned a plethora of new and improved approaches to a wide range of engineering problems. Optimizing test suites is a combinatorial testing challenge that has been demonstrated to be an extremely difficult combinatorial optimization limitation of the research. The authors have proposed an almost infallible method for selecting combinatorial test cases. It uses a hybrid whale–gray wolf optimization algorithm in conjunction with harmony search techniques. Test suite size was significantly reduced using the proposed approach, as shown by the analysis of the results. In order to assess the quality, speed, and scalability of TWGH, experiments were carried out on a set of well-known benchmarks. It was shown in tests that the proposed strategy has a good overall strong reputation test reduction size and could be used to improve performance. Compared with well-known optimization-based strategies, TWGH gives competitive results and supports high combinations (2 ≤ t ≤ 12).
