Preferred Language
Articles
/
dxfTWJMBVTCNdQwChtEZ
Hyperglycosylated hCG in a Group of Iraqi Patients with Gestational Trophoblastic Disease

Background : Hyperglycosylated hCG a newly discovered variant of hCG which can be used as a predictor of invasion of trophoblastic cells in patient with gestational trophoblastic disease. Objectives : To measure hyperglycosylated human chorionic gonadotrophin and to assess how far it can be used as predictor of invasion in invasive mole and choriocarcinoma. Study design control study. Setting: : Case Gynecological department in Baghdad Teaching Hospital from January 2016 to January 2017. Patient and Methods : 60 women were enrolled in this study 30 of them were with gestational trophoblastic disease (no.= 30 ) the remainder were normal pregnancy (no. =30) , hCG –H level was measured in both groups. Results : Mean serum hCG-H level was significantly higher in patients with gestational trophoblastic disease compared to control women (460.5 ± 168.35 , 206.8± 19.99 ) respectively with p value < 0.05. Mean serum hCG-H level was significantly higher in patients with gestational trophoblastic disease Invasive mole and chriocarcinoma compared to patient with molar pregnancy. Before evacuation (772.11 ± 184.08, 398.27 ±65.86). After evacuation (550.52 ± 146.15 , 340.40 ±85.61). With p value < 0.05. Conclusion : 1) Serum hCG-H level was higher in patients who had invasive mole and patients with choriocarcinoma than patients with gestational trophoblastic disease , so it can be used as a predictor of invasion in patients with invasive mole and choriocarcinoma. 2) Serum hCG-H level can be used in patient with abnormal β- hCG after evacuation when it is slowly decreasing or plateau. 3) It is better to measure the ratio hCG-H/total hCG and using uniform method test and units so we can understand the actual changes that happen in invasion.

Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Wed Apr 25 2018
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
On Estimating the Survival Function for the Patients Suffer from the Lung Cancer Disease

          In this paper, the survival function has been estimated for the patients with lung cancer using different parametric estimation methods depending on sample for completing real data which explain the period of survival for patients who were ill with the lung cancer based on the diagnosis of disease or the entire of patients in a hospital for a time of two years (starting with 2012 to the end of 2013). Comparisons between the mentioned estimation methods has been performed using statistical indicator mean squares error, concluding that the estimation of the survival function for the lung cancer by using pre-test singles stage shrinkage estimator method was the best   . <

... Show More
Crossref
View Publication Preview PDF
Publication Date
Tue Feb 28 2023
Journal Name
Iraqi Journal Of Science
Study the Association of Uromodulin Gene rs13332878 with Chronic Kidney Disease

       Uromodulin is the most abundant protein ordinary excreted in urine which could be used as a biomarker to diagnose kidney diseases.  However, evidence suggests that it regulates salt transport, protects against urinary tract infection and kidney stones, and has a role in kidney damage and innate immunity. This study aimed to understand the association of uromodulin gene rs13332878 with  chronic kidney disease. More than 100 people were selected for the study and the samples collected from the under study subjects were divided into two groups. 70 chosen subjects were under the dialysis with kidney failure, and  aged between 18-88 years. The second group included 30 samples from healthy individuals, used as control. One of t

... Show More
Scopus Crossref
View Publication
Publication Date
Thu Jun 25 2020
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Evaluating the Clinical Outcomes of Three Medication Regimens for Treating a Sample of Iraqi Persistent Asthmatic patients

Abstract

    Asthma is a complex disease defined by chronic airway inflammation and airflow limitation causing variable respiratory symptoms which include shortness of breath (SOB), wheezing, chest tightness and cough. Asthma guidelines advocate adding a second long acting bronchodilator to medium doses of inhaled corticosteroids (ICS) rather using high doses of ICS alone to control moderate to severe persistent asthma. The aim of this study was to evaluate the clinical outcomes of three medication regimens indicated for Iraqi patients suffering from persistent asthma. 

    This study was interventional randomized clinical study conducted on a sample of adult Iraqi asthm

... Show More
Scopus (2)
Crossref (1)
Scopus Crossref
View Publication Preview PDF
Publication Date
Thu Jun 25 2020
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn: 1683 - 3597 , E-issn : 2521 - 3512)
Evaluating the Clinical Outcomes of Three Medication Regimens for Treating a Sample of Iraqi Persistent Asthmatic patients

Abstract     Asthma is a complex disease defined by chronic airway inflammation and airflow limitation causing variable respiratory symptoms which include shortness of breath (SOB), wheezing, chest tightness and cough. Asthma guidelines advocate adding a second long acting bronchodilator to medium doses of inhaled corticosteroids (ICS) rather using high doses of ICS alone to control moderate to severe persistent asthma. The aim of this study was to evaluate the clinical outcomes of three medication regimens indicated for Iraqi patients suffering from persistent asthma.      This study was interventional randomized clinical study conducted on a sample of adult Iraqi asthmatic patients in Baghdad City. The study com

... Show More
Scopus (2)
Crossref (1)
Scopus Crossref
Preview PDF
Publication Date
Tue Jan 01 2019
Journal Name
Indian Journal Of Public Health Research &amp; Development
Impact of Breast Feeding Duration on the Presence of <i>Candida</i> in Relation to Nonnutritive Sucking Habit among Group of Iraqi Children

Crossref
View Publication
Publication Date
Fri Nov 24 2023
Journal Name
Iraqi Journal Of Science
Antineutrophil cytoplasmic antibodies in patients with tuberculosis

Tuberculosis is caused by Mycobacterium tuberculosis; it is considered as one of the most common, infectious diseases and major causes of morbidity and mortality worldwide. A prospective study was conducted to obtain more clarification about the impact of causative agent and its treatment to enhance autoantibodies production such as ANCA and BPI which used as diagnostic markers for several diseases, and to provide further insight into the classical risk factors (age and sex).Seventy patients with tuberculosis involved in this study, 35 of them were untreated and 35 with treatment administration these patients were attending to directorate of general health national reference laboratory in Baghdad during the period between November/ 2012

... Show More
View Publication Preview PDF
Publication Date
Sun Jan 03 2010
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Cytokine Profile in Patients with Rheumatoid Arthritis

Background: Cytokines produced by inflammatory cells play a pivotal role in synovial inflammation and joint destruction in rheumatoid arthritis.
Patients and Methods: The cytokine serum levels were measured by EASIA (Enzyme amplified sensitivity immunoassay) in sera from 50 RA patients, and 40 healthy donors. Cytokine levels were compared in different RA subpopulations (positive or negative rheumatoid factor (RF), long term or recent onset disease, high or low disease activity). In addition, the possible association with other demographic and clinical parameters (gender, age, etc) was also analyzed.
Results: It was demonstrated that IL-2, IL-6 and IFN-δ levels were elevated in serum samples of RA pati

... Show More
Crossref
View Publication Preview PDF
Publication Date
Sun Jul 04 2010
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Renal Dysfunction in Patients with Heart Failure

Background: The coexistence of renal and heart failure carries an extremely bad prognosis. The exact cause of deterioration of kidney function and the mechanism underlying this interaction are complex, multifactorial in nature, and still not completely understood. Both the heart and the kidney act in tandem to regulate blood pressure, vascular tone, diuresis, natriuresis, etc.
Patients and methods: Sixty patients mean age 65.5 year were complaining heart failure duo to different causes assessed for renal function (blood urea &creatinine) and cardiac function by echocardiography in day 0 and 10 day after treatment of heart failure.
Results: The mean value (±S.D) of blood urea and serum creatinine on day 0 were 64.17mg/dL (±30.

... Show More
Crossref (1)
Crossref
View Publication Preview PDF
Publication Date
Thu Apr 01 2021
Journal Name
Biochem. Cell. Arch
STUDY ON THE MUTATION OF ASXL1 IN ACUTE MYELOID LEUKEMIA IN IRAQI PATIENTS

The present study was designed to shed light on the molecular effects caused by acute myeloid leukemia (AML). It was also aimed to investigate ASXL1 point mutations in newly AML patients as compared to healthy control. The study comprised of 43 AML Iraqi patients and their ages ranged between 16-75 years. It included 23 females and 20 males compared with 20 healthy controls. Results revealed that the extracted DNA from 30 AML patients and amplified by PCR to obtain ASXL1 gene from exon 12 showed larger bands (479). Among forty three patients, two of them displayed point mutations of deletion and substitution, while the others were normal since no mutations were detected. The total of mutations in two mutated patients was 27 mutations, the m

... Show More
Scopus
Preview PDF
Publication Date
Sun Apr 03 2005
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Possible Role of Interleukins 6 and 10 in Colorectal Carcinoma in Iraqi Patients

Background : It is quite accepted that interleukins (IL) in general play a crucial role in response to injuy , infection and on cogenic trans formation , among there are IL-6 and ILJO.
Aim of this study is to find out the possible role of IL_ and IL, 10 in colo rectaI carcima in Iraqi patients.
Subjects and Methods: forty patients with colorectal cancer (CRC) composed with 30 healthy controls were enrolled in this study. Serum conc. Of IL-6 and IL -lOwere estimated in both groups using ELIZA technique.
Results: Serem levels of IL-6 and IL-10 were significantly increased (P<0.001) in compassion with control group.
Conclusion: these cytokins could be used as a markers for tumor progression .

Crossref
View Publication Preview PDF