...Show More Authors
Background: Fast dissolving oral drug delivery system is solid dosage form which disintegrates or dissolves within second
when placed in the mouth without need of water or chewing. In present investigation, an attempt has been made to develop oral
fast dissolving film of calcium channel blocker lacidipine. Method: Five formulas were prepared by solvent casting method
using HPMC (METOLOSE)® as a film forming polymer and evaluated for their physical characteristics such as thickness,
weight variation, folding endurance, drug content, disintegration time and in vitro drug release. The compatibility of the drug
in the formulation was confirmed by FTIR and DSC studies. Result and Conclusion: The optimized formula F1 showed
minimum in vitr
...
Show More