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Antimicrobial Activity of Silver Nanoparticles on Pathogenic Bacteria
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Nosocomial infection is acquired contamination of hospitals and health care units caused by multidrug resistant bacteria. Currently, bacterial resistance to antimicrobial medication represents a complicated public health problem. Recent studies on the antimicrobial activity of silver nanoparticles (AgNPs) attracted researchers worldwide to focus on the safe synthesis of AgNPs as antimicrobial agents against multidrug resistant bacteria. The antimicrobial efficacy of AgNPs on pathogenic bacteria isolated from clinical cases of acquired hospital infection was targeted in this project. Fifty specimens of stool were collected through private laboratories in Baghdad from patients who suffered diarrheal symptoms. Bacterial isolation, identification, and characterization via culturing on MacConkey agar, Salmonella shigella agar, and IMVic analysis were done besides, using polymerase chain reaction (PCR) through amplifying inf B gene for molecular characterization. The obtained isolates were tested for antimicrobial sensitivity via disk diffusion assay against; Gentamycin, Amoxicillin, Tetracycline, Ceftriaxone and a suspension of silver nanoparticles (1mM AgNo3 reduced by 1% tri-sodium citrate). Results of isolation and IMVic showed the obtained isolates were Klebsiella spp., Enterobacter spp., Citrobacter spp., and PCR assay confirmed their pathogenicity. Disc diffusion assay showed the sensitivity of the isolates (mm); Gentamycin (24.94 ± 0.1), Amoxicillin (2.11 ± 0.13), Tetracycline (12.15 ± 0.1), Ceftriaxone (12.35 ± 0.1). Whereas, all isolates are sensitive to AgNPs (24.12 ± 0.3). This result of the antimicrobial effect of AgNPs on nosocomial infection promises for developing AgNPs solution as a product used in the sterilization of furniture, floors and hospital water cycles

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Publication Date
Thu Jan 01 2015
Journal Name
Chemistry And Materials Research
Anticancer Activity of New Di-Nuclear Copper (I) Complex
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In-vitro biological activities of the free new H4L ( indole-7-thiocarbohydrazone) ligand and its Ni(II), Pd(II) , Pt(II), Cu(II), Ag(I), Zn(II) and Cd(II) complexes are screened against two cancerous cell lines, that revealed significant activity only for [Cu2Cl2(H4L)2(PPh3)2] after 72 h treatment by the highest tested concentrations. The Copper(I) complex was characterized by X-ray Crystallography and the NMR spectra, whereas it has been confirmed to have momentous cytotoxicity against ovarian, breast cancerous cell lines (Caov-3, MCF-7). The apoptosis-inducing properties of the Cu(I) complex have been investigated through fluorescence microscopy visualization, DNA fragmentation analysis and propidium iodide flow cytometry.

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Publication Date
Mon Jul 01 2019
Journal Name
Journal Of Physics: Conference Series
Production and antibacterial activity of biosurfactant from Saccharomyces cerevisiae
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Abstract<p>A total of four types of instant dry yeast <italic>Saccharomyces cerevisiae</italic> which are Gloripan, Swan, Super Man (China) and Saf (Turkey), were obtained from the local market in Baghdad, Iraq. All the types were identified according to their morphological characteristics and screened for their ability to produce biosurfactant by oil spread method. Biosurfactant was extracted and partially purified by precipitation with ammonium sulfate at saturation ratio75%. Antibacterial activity of crude and partially purified biosurfactant was tested against twenty isolates of <italic>Pseudomonas aeruginosa</italic> and the results showed that crude biosurfactant has no</p> ... Show More
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Publication Date
Mon Mar 27 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Phytochemical Investigation and Antioxidant Activity of Iraqi Tribulus terrestris
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The aim of the present study was to characterize the Iraqi Tribulus terrestris for the presence of biologically active phyto-chemicals using methanolic extracts of the plant (aerial parts) by Gas Chromatography –Mass spectrometry (GC/MS), while the mass spectra of the compounds found in the extract was matched with the National Institute of Standards and Technology (NIST) library , in addition to study the antioxidant activity of plant extract , results confirmed the presence of therapeutically potent compounds in the Iraqi Tribulus terrestris extract predominantly alkaloids, flavonoids, saponins, tannins and terpenoids. Antioxidant potential of Iraqi Tribulus terrestris

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Publication Date
Fri Jan 01 2016
Journal Name
Kmitl Science And Technology
Antibacterial Activity of Lactobacillus buchneri Bacteriocin against Vibrio parahaemolyticus
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Eleven yoghurt samples were collected from local markets in Baghdad to isolate Lactobacillus buchneri. Only 3 isolates of L. buchneri were found and the isolate No. 3 was the most producer of bacteriocin. Bacteriocin was adsorbed 100% onto silicic acid at pH 6.0-7.0. Below or above these pH values, adsorption was decreased, ranging between 35 and 90%. Therefore, pH 6.0 was used for the purification procedure. The purification procedure including silicic acid adsorption/desorption and cation-exchange chromatography (CEC) resulted in a 11.11 fold increase in the final specific activity of pure bacteriocin (1176.47 Au/mg) compared to the culture supernatant which was 32.64 Au/mg. The molecular weight was determined to be about 3.4 kDa. The bac

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Publication Date
Sun Mar 01 2020
Journal Name
International Journal Of Pharmaceutical Research
Antibacterial activity of lectin-like bacteriocin extract from P.putida
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Publication Date
Mon Nov 14 2022
Journal Name
Biomedicine
Antibacterial activity of klebocin against methicillin resistance Staphylococcus aureus
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  Introduction and Aim: Bacteriocins are antimicrobial peptides that have bactericidal and/or bacteriostatic activity against other bacteria. The aim of this study was to assess the antibacterial efficiency of Klebocin a K. pneumoniae bacteriocin, against biofilm formation by clinical isolates of methicillin resistant Staphylococcus aureus MRSA.   Materials and Methods: S. aureus isolated from clinical samples was identified according to vitek 2 system Antibiotic susceptibility test was performed according to disc diffusion method. Vitek 2 compact system was also used to detect MRSA strains. Agar well diffusion method was used to evaluate the antibacterial activity of klebocin from K. pneumoniae towards 11 strains of S. aureus by

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Publication Date
Sun Mar 24 2024
Journal Name
مجلة العلوم التربوية والنفسية
إقامة البرهان على من ادعى مخالفة النعمان في مسائل من الحدود
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إن اختلاف الفقهاء مصدر عظيم لثروة فقهية كبيرة، ومن مظاهر الخلاف الفقهي مؤاخذات علمية يوردها بعض العلماء على علماء آخرين بدعوى مخالفتهم الأدلة الشرعية، أو القواعد المقررة لاستنباط الأحكام الشرعية، ومن تلك المؤاخذات ما أورده الإمام المحدث أبو بكر ابن أبي شيبة رحمه الله تعالى على أبي حنيفة النعمان رحمه الله حيث إنه ساق في مصنفه الكثير من الأحاديث والآثار التي عد الإمام أبا حنيفة رحمه الله مخالفا لما تقتضيه من

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Publication Date
Wed Apr 02 2025
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Green Synthesis and Characterization of Vanadium Oxide Nanoparticles using Plant Extract
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This study employed the biosynthetic technique for creating vanadium nanoparticles (VNPs), which are affordable and user-friendly; VNPs was synthesized using vanadium sulfate (VOSO4.H2O) and a plant extract derived from Fumaria Strumii Opiz (E2) at a NaOH concentration of 0.1 M. This study aims to investigate the potential applications of utilizing an adsorbent for metal ions to achieve environmentally friendly production and assess its antibacterial activity and cytotoxicity. The reaction was conducted in an alkaline environment with a pH range of 8–12. The resulting product was subjected to various characterization techniques, including Fourier transform infrared spectroscopy, ultraviolet-visible spectroscopy, x-ray diffraction (XRD), t

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Publication Date
Tue Aug 01 2023
Journal Name
Journal Of Materials Science: Materials In Electronics
Fabrication and characterization of CoxMn0.25−xMg0.75Fe2O4 nanoparticles for H2S sensing applications
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Publication Date
Fri Jun 20 2025
Journal Name
Journal Of Kufa For Chemical Sciences
Biosynthesis of Zirconium Oxide Nanoparticles from Different Plant Extracts: A Review
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