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bsj-7594
Lead acetate deteriorates the improvement effect of L-arginine and tetrahydrobiopterin on endothelin-1 receptors activity in rat aorta
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Endothelin-1 (ET-1) is a potent vasoconstrictor hormone that has been identified as an important factor
responsible for the development of cardiovascular dysfunctions. ET-1 exerts its vasoconstrictor activity
through two pharmacologically distinct receptors, ETA and ETB that are found in vascular smooth muscle
cells (VSMCs) and the vasodilator activity through an ETB receptor located on endothelial cells. This study
aimed to show the impact of 1µM L-arginine (LA), 100µM tetrahydrobiopterin (BH4), and their combined
effect on ET-1 activity in both lead-treated and lead-untreated rat aortic rings. This means, investigating how
endothelial dysfunction reverses the role of nitric oxide precursor and cofactor. In this study, Rat aortic rings
have been pre-incubated with BH4, LA and their combination. Subsequently, the aortic rings were preincubated with 200µM N-Nitro-L-arginine methyl ester (L-NAME) and 0.5µM BQ-123. Then, the vascular
response to cumulative doses of rat ET-1 was analyzed in each of the above-mentioned groups (LA, BH4, LA
& BH4, L-NAME, BQ-123), in the presence and absence of lead acetate 1µM Pb (C2H3O2)2. ET-1 efficacy and
potency were significantly decreased in the presence of LA, BH4, and LA and BH4 combination in the untreated
group, while it significantly increased in the presence of lead. In the second trial of experiments ET-1 efficacy
markedly decreased in BQ-123- incubated cells in both lead-treated and untreated aortic rings. In the presence
of lead, the efficacy of ET-1 was raised with the use of L-NAME. In conclusion, LA and BH4 can be considered
pharmacological agents to alter the potency of ET-1-induced vasoconstriction and concomitantly lower blood
pressure.

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Publication Date
Sun Jun 18 2023
Journal Name
Arab Science Heritage Journal
أضواء على نشأة مدينة الفلوجة وتطورها
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The study search for the history and the beginning of Faluja city in addition to its growing and developing stages , as well as its planning nature through ottoman era depending on aerial map of Falluja in 1919 as it is the oldest map from Baghdad Real Estate Department, this mentioned map is characterized by the accuracy of the information,

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Publication Date
Sun Feb 25 2024
Journal Name
Baghdad Science Journal
Hybrid CNN-based Recommendation System
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Recommendation systems are now being used to address the problem of excess information in several sectors such as entertainment, social networking, and e-commerce. Although conventional methods to recommendation systems have achieved significant success in providing item suggestions, they still face many challenges, including the cold start problem and data sparsity. Numerous recommendation models have been created in order to address these difficulties. Nevertheless, including user or item-specific information has the potential to enhance the performance of recommendations. The ConvFM model is a novel convolutional neural network architecture that combines the capabilities of deep learning for feature extraction with the effectiveness o

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Publication Date
Thu Jul 01 2010
Journal Name
Political Sciences Journal
ملاحظات اولية على قانون الانتخابات ونتاجاتها
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ملاحظات اولية على قانون الانتخابات ونتائجها

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Publication Date
Mon Aug 01 2011
Journal Name
مجلة الحقوق كلية القانون الجامعة المستنصرية
اثر انعدام الاهلية على الشركة التضامنية
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اثر انعدام الاهلية على الشركة التضامنية

Publication Date
Wed Nov 02 2022
Journal Name
الجامعة العراقية
الحاجات الارشادية وعلاقتها بالانفتاح على الخبرة
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Publication Date
Wed Oct 11 2023
Journal Name
Journal Of Educational And Psychological Researches
Cognitive Behavioral Therapy for Internet Addicts
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The study aims to explore the effect of cognitive behavioral therapy on internet addiction among university students. The experimental method was used. The study population consisted of (100) university students (50 males, 50 females). The Research sample included (13) University students at Baghdad University addicted to the Internet (9 males, 4 females), divided into two groups:  a control group consisting of (6) individuals (4 males, 2 females) and an experimental sample consisting of (6) individuals (4 males, 2 females). The Scale of Internet Addiction by Young (1996), which was translated and modified into the Arabic language by (Moegel and Prism, 2016), was administered to the study sample. The sample was subjected to two sess

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Publication Date
Sun Feb 25 2024
Journal Name
Baghdad Science Journal
Containerized Event-Driven Microservice Architecture
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Microservice architecture offers many advantages, especially for business applications, due to its flexibility, expandability, and loosely coupled structure for ease of maintenance. However, there are several disadvantages that stem from the features of microservices, such as the fact that microservices are independent in nature can hinder meaningful communication and make data synchronization more challenging. This paper addresses the issues by proposing a containerized microservices in an asynchronous event-driven architecture. This architecture encloses microservices in containers and implements an event manager to keep track of all the events in an event log to reduce errors in the application. Experiment results show a decline in re

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Publication Date
Sat Nov 02 2024
Journal Name
العلوم القانونية والسياسية
الحروب والصراعات وتداعيتها على الامن الانساني
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تعد الحروب و الصراعات واحدة من اقدم الظواىر التي عرفتها المجتمعات البشرية وان ىذه الظاىرة تجسدت في البداية على مستوى الصراعات الفردية عندما كانت ترتقي الى مستوى الاشتباك وكانت بدائية في وسائلها وادواتها ،وكما ان ظاىرة الحرب بدأت من الاسرة ومن ثم القبيلة والعشيرة وانتهت بالدولة ،اذ ان ظاىرة الحروب بشكلها التقليدي تأخذ شكلا تدميريا بعد ان تتطور ابعادىا القصوى وان حدوثها ىو تضارب مصالح واىداف الاطراف وانها ال

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Publication Date
Mon Dec 01 2008
Journal Name
Political Sciences Journal
تأثير تكوين الشخصية على السلوك السياسي
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تأثير تكوين الشخصية على السلوك السياسي

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Publication Date
Sun Jun 20 2021
Journal Name
Baghdad Science Journal
Projective MDS Codes Over GF(27)‎
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MDS code is a linear code that achieves equality in the Singleton bound, and projective MDS (PG-MDS) is MDS code with independents property of any two columns of its generator matrix.   In this paper, elementary methods for modifying a PG-MDS code of dimensions 2, 3, as extending and lengthening, in order to find new incomplete PG-MDS codes have been used over . Also, two complete PG-MDS codes over  of length  and 28 have been found.

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