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bsj-7245
The role of Adipocytokines, Vitamin D, and C in Colorectal Cancer
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Colorectal cancer is the world's 3rd most frequent malignant neoplasm and the 4th most common cancer in Iraq. Leptin and Adiponectin are two major Adipocytokines produced by adipose cells that have opposite effects on the formation of colorectal tumors. Leptin induces tumor growth and metastasis, whereas Adiponectin inhibits it. 1,25-Dihydroxyvitamin D controls and limits cancer cell proliferation, differentiation, and survival. Vitamin C deficiency, on the other hand, has been regularly detected in cancer tissues and has potent anti-cancer properties. The purpose of this study was to look at the biochemical role of circulatory Adipocytokine levels (Adiponectin and Leptin) as well as the anti-cancer potentials of Vitamin D and C in CRC patients from Iraq. The research looked at confirmed cases of CRC who were seen at Nanakali Hospital for Blood diseases and Cancer in Erbil before their treatment sessions. A total of 35 patients with confirmed CRC cases and 36 healthy participants who were age, gender, and BMI matched were recruited. ELISA technique was used to quantify serum levels of Adiponectin, Leptin, Vitamin D, & C. The results showed a significant increase (P<0.0001) of serum Adiponectin levels (12.06±1.59) in CRC patients relative to the controls (2.05±0.96). On the contrary, the serum Leptin levels (24.09±2.92) were non-significantly lower (P=0.098) in CRC patients in comparison to controls (53.84±1.54). Furthermore, serum Vitamin D (13.14±1.21) and Vitamin C (1.03±0.10) levels in CRC patients were significantly lower (P<0.0001) when compared to controls (24.49±1.47, 5.78±2.16), respectively. The findings in the current study suggest an imperative biochemical role of Adipocytokines (Adiponectin and Leptin) and Adipose tissue dysfunction in the pathogenesis of CRC patients. Furthermore, decreased serum levels of Vitamin D and C reduce their effective anti-cancer effects, allowing Colorectal malignant neoplasms to survive and develop. Thus, the present study findings suggest Adiponectin and Leptin as potent prognostic and risk factors of CRCs. Also, Vitamin D and C deficiencies are the major risk factors among Iraqi CRC patients.

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Publication Date
Thu Oct 01 2015
Journal Name
Journal Of Educational And Psychological Researches
دور الإرشاد النفسي في تحقيق جودة الحياة بالمجتمع المعاصر
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     Psychological Counseling Services occupies a high position in the developed countries and that for its psychologist services for different sectors of the community members, and has been popularized until recently the wrong concept of the effect, that the psychological service is provided only to the owners of behavior is normal only, Vantage him neglect to provide psychological services a large segment of the community members who are in dire need of these services.

      The counseling service is part of a global social movement seeking to emphasize the quality of life of the human and the emphasis on the value and dignity and the need to live a quiet lif

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Publication Date
Sun Jul 07 2013
Journal Name
Journal Of Educational And Psychological Researches
دور الاسرة العراقية في غرس المنظومة القيمية لدى ابنائها
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The family is e Social first come into contact with filial friction direct and continuing as is the social environment the first to grow the patterns of socialization that make up the life of the individual in the future , especially in forming the personality of both social and cultural , the family's work to lay the foundations of standards called the system value , which is ( religious teachings - customs - traditions - norms ) and is on its way interaction values ​​between family members as well as the transfer of expertise , knowledge and models of behavioral by parents to their children , which will be in accordance with the type of interactions and social relations is also affected dev

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Publication Date
Mon May 01 2023
Journal Name
المجلة العراقية للبحوث الانسانية والاجتماعية والعلمية
دور المحاسبة القضائية في تعزيز اداء مراقب الحسابات الخارجي
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٠ اش١جخ ٗزفقث ٌٟبِ ٟجعبؾٌّا تٔبغٌا ٟف بقزخِ ٟئبنل ( ًئاضل بساحم ) توهم ىلع ءىضلا طٍلسحو بلارم ءادأ ىلع اهرٍثأحو تٍوهملا اهحاءارجإو تمذخخسملا اهحاٍومح ثٍح نم تٍئاضملا تبساحملا دبثبغؾٌا . اسبِٙٚ د ءبمٌلأ ٟمبٌّا ـؾف ٍٝػ ض١وشزٌا يلاخ ِٓ خ١ٔٛٔبمٌا سِٛلأبث خفشؼٌّا ءٛم ٟف دب٠شؾزٌا ًجمزغٌّا ٍٝػ حشظٔ ٌا خجعبؾٌّا ْا شؽبجٌا ظزٕزعاٚ ذٍجٌٍ ٞدبقزللاا َذمزٌا خٍغػ غفد ٟف ُٙغر خ١ئبنم ، خجعبؾٌّا ٟف خِذخزغٌّا خض٠ذؾٌا ت١ٌ

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Publication Date
Sun Jan 05 2014
Journal Name
Journal Of Educational And Psychological Researches
دور المؤسسات التربوية في ترسيخ قيم النزاهة لدى الناشئة
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   The research aims to identify the role of educational institutions in instilling the values ​​of integrity among emerging in word and deed and identifies research in educational institutions that have a significant impact in the emerging figures such as (family , school , media , mosque , civil society organizations , youth clubs .Have been identified the most important search terms of ( values ​​,educational institutions , Integrity) also touched search particular concern values ​​education and its impact on emergent behavior , then separate search in the role of each educational institution to establish moral values ​​in general and the values ​​of integrity, particularly in the behavior of emerging

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Publication Date
Fri Mar 01 2019
Journal Name
مجلة الحقيقة الجزائر
دور الإدارة المصرفية الرشيدة في ضمان مخاطر الائتمان المصرفي
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دور الإدارة المصرفية الرشيدة في ضمان مخاطر الائتمان المصرفي

Publication Date
Sat Jan 01 2022
Journal Name
دور تحرير تجارة الخدمات في تنشيط الاستثمار الاجنبي بالعراق
دور تحرير تجارة الخدمات في تنشيط الاستثمار الاجنبي بالعراق
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Publication Date
Sun Sep 19 2021
Journal Name
Journal Of Al-rafidain University College For Sciences ( Print Issn: 1681-6870 ,online Issn: 2790-2293 )
دور فلسفة الذكاءات المتعددة في تفعيل مفاهيم اليقظة الاستراتيجية - بحث وصفي تحليلي لآراء عينة من المدراء العاملين في وزارة الصناعة والمعادن
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تناول البحث أبعاد الذكاءات المتعددة كمتغير مستقل بأبعاده الفرعية الثمانية ( الذكاء الاجتماعي ،الذكاء الطبيعي، الذكاء البصري، الذكاء المنطقي، الذكاء اللغوي، الذكاء الموسيقي، الذكاء الحركي/الحسي، الذكاء الشخصي/ البيئي) واليقظة الاستراتيجية كمتغير تابع بأبعاده الفرعية الثلاثة ( اليقظة التجارية، اليقظة التنافسية ، اليقظة التكنولوجية) وقد تم اختيار عينة من المديرين العاملين في وزارة الصناعة والمعادن، فق

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Publication Date
Sat Apr 01 2023
Journal Name
مجلة كلية بغداد للعلوم الاقتصادية الجامعة
دور استراتيجية الانتاج الانظف في حماية البيئة وتخفيض التكاليف
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ان حماية البيئة وتخفيض التكاليف من األهداف التي تسعى الوحدات االقتصادية الى تحقيقها لكي تتماشى مع التوجه العالمي لحماية الموارد الطبيعية وإنتاج منتجات صديقة للبيئة وفي الوقت نفسه التخلص من االلتزامات التي تتحملها الوحدات االقتصادية من تكاليف بيئية وغر امات مما يؤدي الى ارتفاع كلف االنتاج ، يهدف البحث الى دراسة المرتكزات المعرفية الستراتيجية اإلنتاج األنظف وتحديد التكاليف التي يمكن تخفيضها خالل مراحل اا

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Publication Date
Fri Nov 21 2025
Journal Name
Kufa Journal Physical Education Sciences
دور الاعداد التكنلوجي للطالبات في التفاعل مع التعليم الالكتروني
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Publication Date
Sun Jan 03 2016
Journal Name
Journal Of Educational And Psychological Researches
دور الإرشاد النفسي في تحقيق جودة الحياة بالمجتمع المعاصر
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 Psychological Counseling Services occupies a high position in the developed countries and that for its psychologist services for different sectors of the community members, and has been popularized until recently the wrong concept of the effect, that the psychological service is provided only to the owners of behavior is normal only, Vantage him neglect to provide psychological services a large segment of the community members who are in dire need of these services.

                The counseling service is part of a global social movement seeking to emphasize the quality of life of the human and the emphasis on the value and dign

... Show More
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