Rheumatoid arthritis (RA), is an autoimmune, and inflammatory disease that is closely related to the destruction of cartilage and bone. DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. Recent evidence has demonstrated that DC-SIGN is involved in the pathophysiological of chronic inflammation, so DC-SIGN has been linked to several autoimmune and may play an essential indicator in the pathogenesis and progression of RA. Therefore, the purpose of this study is to determine the serum level of DC-SIGN in RA patients, as well as the level of DC-SIGN based on demographic characteristics. Fifty Iraqi RA patients were enrolled in the study, and a control sample of 38 healthy individuals (ascertain by laboratory and clinical tests) were included and matched by gender, age, and ethnicity with the patients. The DC-SIGN concentration was calculated in the patients’ serum and compared to control using the ELISA assay and the results revealed significantly increased serum level of DC-SIGN (12.047 ± 1.114 vs. 6.863 ± 0.806 ng/ml) was recorded in RA patients compared to controls. When correlating results, it was shown that the concentration of DC-SIGN in the serum did not record a significant difference between gender and age, as well as the blood groups. To determine the impact of the therapeutic status in RA patients on the DC-SIGN level, it was found that the concentration of DC-SIGN level was higher in untreated patients compared to treated patients. Regarding viral infection, when an investigation was conducted in RA patients infected with SARS-CoV-2, the serum level of DC-SIGN in RA patients with COVID-19 showed no change in concentrations compared to uninfected RA patients.
Praise be to God, Lord of the worlds, and may blessings and peace be upon the most honorable of all creation, Abi Al-Qasim Muhammad, who is the messenger of mercy to the worlds and upon the God of the pure and good companions all
احكام التركز الاقتصادي للمشاريع دراسة مقارنة
The problem of informal settlements in Iraqi is one of the most serious problems due
to its economic, social and security impacts which jeopardize the society safety and stability.
This study investigates the present situation of informal settlements in the Baghdad
governorates as well as approaches followed in making decisions to either upgrade or remove
those areas. Requirements of each decision are also discussed.
Study methods relied on both office and field studies to collect data and information
needed. The study revealed important findings that would help take appropriate measures that
deal with the informal settlements in Iraqi. The study also proposes effective mechanisms to
preclude both an increase in c
تضطلع المصارف على اختلاف انواعها بعمليات كثيرة متطورة, نظمها قانون التجارة رقم (30) لسنة 1984 في الفصل الثاني من الباب الرابع . و العمليات المصرفية على تنوعها تؤثر في الحياة الاقتصادية للبلد بشكل مباشر وان نجاح المصارف او اخفاقها في ممارسة هذه العمليات ينعكس هو الاخر على النشاط الاقتصادي في بقية القطاعات، مما يقتضي اخضاع المصارف الى رقابة واشراف البنوك المركزية لضبط اعمالها وتوجيهها وجهة سليمة تخدم مصالح ج
... Show Moreتدور فكرة هذا البحث عن كيفية خلق الله تعالى للعالم؟
Stop the search on the performance of the stylistic literary messages sent by
Abu Mohammed Amer bin Said Altakrna to the kings of his time and Ullach
highlighting the method of the three levels is psychological and away the consignee
and the receiver Taster literary text.
Level voice and rhythmic, which dealt with (alliteration and Naturalization
voice, and repetition and parallelism, and rhyme and toning) and its impact on the
taste and the emotional art between the sender and the receiver Bashklah.
Who has studied the structural level (introductory sentence order methods in the
messages, generally have much style presentation and brief delays and actor, and
then end the moral and intellectual martyrdom and de
لقد نشا علم التحقيق على ايدي المحدثين المسلمين الذين وضعوا قواعد هذا العلم وظهرت مؤلفات عدة في هذا المجال ، لكن ما قام به الاقدمون لم يشكل قواعد علم مستقل بذاته ومنذ ظهور الطباعة بدأت حركة تحقيق المخطوطات ، وتعددت مناهج التحقيق فكان للمستشرقين منهجهم الخاص وظهر منهج التحقيق والاخراج الفني والعلمي للمخطوط .
Alfonso Sastre escribió La Sangre y la ceniza, su primera obra dentro de la llamada “Tragedia Compleja” en los primeros años de la década de los sesenta, pero la primera edición no apareció hasta el año 1967 y fue en lengua italiana. Por causa de la censura la obra estuvo prohibida a lo largo de muchos años, finalmente su primera edición en castellano apareció en el número 1 de la revista Pipirijaina, en octubre del año 1976. El estreno tuvo lugar en el Teatro Villarroel de Barcelona en enero de 1977, a cargo del Colectivo de Teatro ‹‹El Búho›› el cual realizó con este espectáculo una gira por toda España y más tarde lo ha representado en los Festivales Internacionales de T
... Show MoreEducation represents a different their areas, especially after the educational cornerstone of Staff of the community in which young person’s that can stand up and shared the overall development process.
In order for education to be effective in the community, there is a need to develop to cope with the process development of civilization and modern technology. And for that to be achieved the goal of current research to stand on the advancement of the educational process through Knowledge of educational strategies that had previously requirements put forward for the development of educational process as well as through Knowledge of the mo
... Show More