Rheumatoid arthritis (RA), is an autoimmune, and inflammatory disease that is closely related to the destruction of cartilage and bone. DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. Recent evidence has demonstrated that DC-SIGN is involved in the pathophysiological of chronic inflammation, so DC-SIGN has been linked to several autoimmune and may play an essential indicator in the pathogenesis and progression of RA. Therefore, the purpose of this study is to determine the serum level of DC-SIGN in RA patients, as well as the level of DC-SIGN based on demographic characteristics. Fifty Iraqi RA patients were enrolled in the study, and a control sample of 38 healthy individuals (ascertain by laboratory and clinical tests) were included and matched by gender, age, and ethnicity with the patients. The DC-SIGN concentration was calculated in the patients’ serum and compared to control using the ELISA assay and the results revealed significantly increased serum level of DC-SIGN (12.047 ± 1.114 vs. 6.863 ± 0.806 ng/ml) was recorded in RA patients compared to controls. When correlating results, it was shown that the concentration of DC-SIGN in the serum did not record a significant difference between gender and age, as well as the blood groups. To determine the impact of the therapeutic status in RA patients on the DC-SIGN level, it was found that the concentration of DC-SIGN level was higher in untreated patients compared to treated patients. Regarding viral infection, when an investigation was conducted in RA patients infected with SARS-CoV-2, the serum level of DC-SIGN in RA patients with COVID-19 showed no change in concentrations compared to uninfected RA patients.
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« This paper presents the indicators of the development of excellent public relations in the institutions of higher education that are possible for three contextual variables: institutional, professional, professional, and effective communication. Therefore, the study used six indicators to measure the excellent public relations in institutions of higher education and scientific research. These indicators are based on the theory of excellence in public relations . Research Objectives: The aim of the research paper is to uncover the institutional, professional, and professional indicators of effective communication of excellent public relations in higher education institutions. Resea |
The mihrab is an architectural element created by the Muslims for the necessities of which the direction of Qibla is set in the mosques, and the front stands in it during the prayer so as to provide a complete description of the Muslims inside the chapel. The mihrab has a third benefit in amplifying the voice during the time of prayer, Peace be upon him) and the Mosque of Damascus, the Mosque of Kairouan, and the Mosque of Amr Balfstat?.
التجليات الاقتصادية والثقافية والاعلامية للعولمة في العالم الثالث
يعد الالف الأول قبل الميلاد هو عهد ازدهار عظيم للعصر الأشوري الحديث إذ يمتد هذا التاريخ من بداية حكم آدد نراري الثاني عام 911 قبل الميلاد وحتى نهاية حكم الاشوريين السياسي عام 612 قبل الميلاد عندما سقطت نينوى على ايدي المقاتلين الميديين والكلدانيين الذين تحالفوا ضد الاشوريين،و وصل الأشوريون في هذا العهد قمة مجدهم في جميع النواحي العسكرية والسياسية حتى أن سلطتهم وصلت الى معظم انحاء
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مشكلة البحث وآهميته :
تعد مرحلة ما قبل المدرسة من المراحل شديدة الأهمية في نمو الأطفال في هذه المرحلة تمتد رغبة الطفل في التعرف على العالم المحيط به ثم تتطور أنشطته لتصبح أكثر عمقا وأتساعا فتتضمن البيئة البعيدة عنه ، هذا فضلا على أن 50% من التنمية الذهنية للطفل تتشكل في السنوات الأربع الأولى من العمر وأن القراءة هي إحدى المكونات الأساسية التي تعززهذا الجانب من التنمية .
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... Show MoreWhat linguists mentioned about the infinitive and its use in the linguistic levels of speech, whether with its verb, or what was mentioned in the difference between the infinitive and the noun of the source, are matters that are related to the phenomenon of hearing in speech, a need necessitated by the nature of the linguistic law
The intellectual and revolutionary movements that have emerged since the beginning of the second half of the first century of the Islamic era did not appear suddenly, but must have preceded by a social consciousness, multi-forms, in the forefront of class awareness and religious awareness, and awareness was more painful, Of the society of the Arabian Peninsula - before Islam - feel it and suffer from it, a sense of injustice and tyranny, oppression and humiliation, and the destruction of dignity as well as poverty and hunger, and the injustice of tribal laws, and tyranny of each other and the tyranny of their heads on the tribes members and families belonging to this tribe or hill
The issue, the existence of God Almighty, and the creativity of the universes including the whale, and assets and how diversified, and faith in him and his lordship and divinity, is a delicate issue, and very important and dangerous, and it occupied human thought old and new, and still occupy it until God takes the land and on it. Many complex issues of thought, behavior, and ethics have resulted in the belief of many communities in the existence of the Almighty, having ruled their minds, depicting their beliefs and distancing their thoughts about slippage and abuse. When they looked at the wonders of creatures and the minutes of the assets, they thought about the planetary and astronomical motion systems. His existence was denied by ath
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