Rheumatoid arthritis (RA), is an autoimmune, and inflammatory disease that is closely related to the destruction of cartilage and bone. DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. Recent evidence has demonstrated that DC-SIGN is involved in the pathophysiological of chronic inflammation, so DC-SIGN has been linked to several autoimmune and may play an essential indicator in the pathogenesis and progression of RA. Therefore, the purpose of this study is to determine the serum level of DC-SIGN in RA patients, as well as the level of DC-SIGN based on demographic characteristics. Fifty Iraqi RA patients were enrolled in the study, and a control sample of 38 healthy individuals (ascertain by laboratory and clinical tests) were included and matched by gender, age, and ethnicity with the patients. The DC-SIGN concentration was calculated in the patients’ serum and compared to control using the ELISA assay and the results revealed significantly increased serum level of DC-SIGN (12.047 ± 1.114 vs. 6.863 ± 0.806 ng/ml) was recorded in RA patients compared to controls. When correlating results, it was shown that the concentration of DC-SIGN in the serum did not record a significant difference between gender and age, as well as the blood groups. To determine the impact of the therapeutic status in RA patients on the DC-SIGN level, it was found that the concentration of DC-SIGN level was higher in untreated patients compared to treated patients. Regarding viral infection, when an investigation was conducted in RA patients infected with SARS-CoV-2, the serum level of DC-SIGN in RA patients with COVID-19 showed no change in concentrations compared to uninfected RA patients.
تطوير الاداء الاداري لرؤساء الاقسا العممية في جامعة واتسط في ضوء وظائفيا الادارية د ا رسة ميدانية ىدفت تطوير الاداء الاداري لرؤساء الاقسا العممية في جامعة واسط في ضوء وظائفيا الادارية وت بناء استبانة تكونت 410 وعمى مجموعة مف الخب ا رء مف عمداء ومعاونيف :/ مف = 8 فقرة اذ ت تطبيقيا خلاؿ العا الد ا رسي 4109 اساتذة ورؤساء اقسا باستخدا اسموب دلفي بواقع جولتيف وباعتماد نسبة اتفاؽ 1<% وكاف عددى 81 خبي ا رً وتوصمت الد ا رسة الى
... Show MoreThe environment plays a fundamental role in the production of
poetry. It is often said that poets are the products of their environment.
The environment has a clear impact on poets in terms of their style
and their choice of simple and reader-friendly words, which do not
require linguistic dictionaries but suit the readers.
The research aims to study the contribution of tax information systems to increase tax revenues, and to identify how efficiently used information systems currently by the tax authority and their effectiveness in the detection of irregularities by the tax payers such as the cleclaration of incorrect statements that do not show real results of their business activities or hide information from sources related to their income subject to tax, which would negatively affect the outcome of tax revenues and thus damage important sourse of the public treasury of the states resources. The data of research was collected by studying and analysing the tax information systems used by the General Commission of taxs and its branches and a number of prac
... Show MoreThe research includes a description of the controversial issues mentioned by Ibn Al-Anbari in his book between the Egyptians, Basra and Kufa. The reason for choosing the book is because it
This study aims at measuring the sectarian prejudice attitude with sample of college student and secondary school students. It also aims at detecting the impact of similarities and differences of the sectarian belief with the parents on the development of sectarian prejudice with their parents according the following variables (gender,grade,achievement of the parents).
The study restricted by a sample consists of (Baghdad,Al-mustansiriya,and Al-Qadisiyah) students and the fourth grade students (males and female). To achieve the goal of this study , the researcher built atoll to measure the sectarian prejudice attitude after verifying its psychometric characteristics , after analyzin
... Show MoreThe research deals with one of the rights of women, which Islam granted them, and the pledge of allegiance to women, despite its simple part, represents an important and basic feature of the uniqueness that distinguishes the Islamic religion from all the heavenly religions
تعد الحوكمة من المداخل التي نالت اهتمام العديد من الباحثين والدارسين في مجال الإدارة والسياسة بوصفها إحدى الفلسفات السائدة والمرغوبة في الفترة الحالية , وأصبح ينظر إليها دواء لجميع الامراض التي تعاني منها الأجهزة الإدارية عموماً بالأخص العامة منها . وقد ارتبط هذا المفهوم بمفاهيم إعادة التنظيم Reforme والاصلاح الإداري المجه لتحسين كفاءة وفاعلية أداء تلك الاجهزة وبما ينعكس على مجمل السمات والمميزات التي تتعلق ب
... Show MoreThis study aims to identify human resources development and its role in the development of the insurance industry in the national insurance company, and to inspect how the recruitment requirements for human resource development and its impact in setting up efficient and skilled staff ,good, effective and well prepared based on scientific grounds.
The concept has been identified the insurance industry as well as understanding human resources and its management and development the main requirements that lead to improve performance within the company. Divided into two main functions, the first type is the staff requirements and functions and the second kind is the requirements and functions of human resource development
... Show MoreThe attention of civil society organizations, governments and international non-governmental organizations in recent years has focused on the acute practices adopted by companies with the aim of reducing the tax burden, and the results of these practices have a negative impact on the tax revenues that the state uses to finance public needsThe aim of the research is to measure the impact of the voluntary disclosure of companies on tax planning for the period from 2011 to 2015 and the research community is in the General Tax Authority. The research sample is 6 companies within the private sector in the financial, banking, insurance and industrial fields. The research was based on a special model to measure the optional disclosure,
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