Cardiovascular disease is one of the most common comorbidities associated with enlarged extremities, occurring in 60 % of patients with acromegaly. The aim of this study is to evaluate the relationship of growth hormone and insulin such as growth factor-1 with obesity, dyslipidemia, hyperglycemia, and pro-inflammatory cytokines (IL-2, IL-6, IL-10), as risk factors for cardiovascular disorder in acromegaly patients. Eighty subjects were included and categorized into two groups: 40 acromegaly patients and 40 of the control group. The results indicated weight excess, hyperglycemia, hypertension, lipid disorder, and elevated levels of interleukins (2, 6, and 10). The correlation of both GH and IGF-1 with each of weight, BMI, systolic blood pressure, diastolic blood pressure, FBS, HbA1c, cholesterol, triglyceride, LDL, IL6, IL2, and the atherogenic index was found to be positive and significant. Meanwhile, only IGF-1 was significantly correlated with IL10. We conclude that elevated levels of IL2, IL6, IL 10 and their association with both GH and IGF-1 as well as to lipid disorder, hyperglycemia, and hypertension criteria of acromegaly patients are all risk factors for cardiovascular disease, suggesting the necessary clinical examination for cardiovascular disorder in patients with acromegaly patients.
The concept of education is not actually restricted to children or school students, but rather every person should be educated and followed up if he is intended to grow and prove, with effort and time allocation as to fulfill that goal. Thus , the current paper aims to a thinking education and to educate that thinking in teacher and it is not new to deal with the personal characteristics of teacher in the different scientific , and educational researches . But ,these research did not address the necessity of acquiring the skill of thinking, especially as it affects teacher's presentation of the content of the curriculum or even content outside the curriculum, and therefore, there is n
... Show MoreIraqi provinces suffer many of the environmental problems, appear explained these problems in the city of Basra, Basra, the largest province and is among Iraq's provinces in the annexation of oil fields, which is experiencing an oil production operations of large, it suffers from the burning of gas associated with oil extraction resulting in the emission severe gas process including toxic hydrogen sulfide gas (h2S) and oxides of carbon, sulfur and nitrogen in addition to the release of toxic metal elements such as mercury, arsenic, vanadium, which caused the man many serious diseases. , And perhaps one of the most important of these problems are worsening air quality and increasing cases of air pollution and the deterioration of the qual
... Show MoreMany pharmaceutical molecules have solubility problems that until yet consist a hurdle that restricts their use in the pharmaceutical preparations. Lacidipine (LCDP) is a calcium-channel blocker with low aqueous solubility and bioavailability.
Lipid dosage forms are attractive delivery systems for such hydrophobic drug molecules. Nanoemulsion (NE) is one of the popular methods that has been used to solve the solubility problems of many drugs. LCDP was formulated as a NE utilizing triacetin as an oil phase, tween 80 and tween 60 as a surfactant and ethanol as a co-surfactant. Nine formulas were prepared, and different tests performed to ensure the stability of the NEs, such as thermodyna
... Show MoreIsradipine related to dihydropyridine (DHP) class of calcium channel blockers (CCBs). It is used to treat hypertension, angina pectoris, as well as Parkinson disease. It goes under the BCS class II drug (low solubility-high permeability). The drug will experience extensive first-pass metabolism in liver, thus, oral bio-availability will be approximately15 to 24 %.
The aim of the study is preparing stable oral oil in water (o/w) nanoemulsion of isradipine to promote the colloidial dispersion of isradipine in the nano range, so that it may be absorded by intestinal lymphatic transport in order to avoid hepatic first-pass metabolism (israpidi
... Show MoreBackground: The quantity and the quality of available bone, influence the clinical success of dental implants surgery. Cone beam Computed tomography is an established method for acquiring bone images before performing dental implant. Cone beam computed tomography is an essential tool for treatment planning and post-surgical procedure monitoring, by providing highly accurate 3-D images of the patient's anatomy from a single, low-radiation scan which yields high resolution images with favorable accuracy. The aim of study is the Measurement of alveolar bone (height and buccolingual width) and density in the mandible among Iraqi adult subject using CBCT for assessment of dental implant site dimensions. Material and method: The study sample in
... Show MoreRadiological assessment due to existing of natural occurring radioactive materials
(NORM) in South Rumaila oil field was achieved in this study. Different samples
including soil, sludge, scale, oil, and water were collected from different stages of
oil and gas production in Markazia Degassing Station (SDS) in South Rumaila oil
field. Radioactivity of Ra-226, Th-232 and K-40 were measured using gamma
spectrometry system based on HPGe detector with efficiency of 30%. The results
show that some locations within SDS are contaminated with NORM. The activity of
Ra-226, Th-232 and K-40 range between 18.4 to 312.8, 9.4 to 140.8 and 66.4 to
800.8 (Bq/kg) respectively. The places to be more contaminated among the other
p
Investigation of geotechnical vulnerability (liquefaction) and Zonation of the southern region of the Caspian Sea is my most important aim in terms of destructive earthquakes hazard potential. Past geologic events on the south coast of Caspian Sea indicates that destructive earthquakes lead to the death of numbers in this area. Remained evidence of seismic events happening indicates extensive landslides, liquefaction and soil subsidence in the residential and even natural area. Therefore, in this study determination of geotechnical vulnerability (liquefaction) intensity in southern coast of Caspian Sea against natural forces resulting from earthquakes and coastal construction via geographical information system e
... Show MoreThe study investigates the anion and cation concentrations and their distribution in the Dammam aquifer to assess the groundwater suitability for irrigation and livestock in Sayed Al-Shuhadaa, Karbala, central Iraq. It lies between longitudes 43º 29' 00'' – 43º 40' 00'' E and latitudes (32º 17' 00'' – 32º22' 00'') N. The physicochemical properties, cations and anions were measured in 14 active wells distributed in the study area. The assessment was conducted based on the sodium adsorption rate (SAR), sodium percentage (Na%), electrical conductivity (EC), total dissolved solids (TDS), and Hydrogen number (pH). Groundwater in the study area is very good for livestock and characterised b
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