Aim: To evaluate the cytotoxic activity of newly synthesized a series of novel HDAC inhibitors comprising sulfonamide as zinc binding group and Isatin derivatives as cap group joined by mono amide linker as required to act as HDAC inhibitors. Materials and Methods: The utilization of sulfonamide as zinc binding group joined by N-alkylation reaction with ethyl-bromo hexanoate as linker group that joined by amide reaction with Isatin derivatives as cap groups which known to possess antitumor activity in the designed of new histone deacetylase inhibitors and using the docking and MTT assay to evaluate the compounds. Results: Four compounds have been synthesized and characterized successfully by ART-FTIR, NMR and ESI-Ms. the compounds w

In this work, two groups of nanocomposite material, was prepared from unsaturated polyester resin (UPE), they were prepared by hand lay-up method. The first group was consisting of (UPE) reinforced with individually (ZrO2) nanoparticles with particle size (47.23nm). The second group consists of (UPE) reinforced with hybrid nanoparticles consisting of zirconium oxide and yttrium oxide (70% ZrO2 + 30% Y2O3) with particles size (83.98nm). This study includes the effect of selected volume fraction (0.5%, 1%, 1.5%, 2%, 2.5%, 3%) for both reinforcement nano materials. Experimental investigation was carried out by analyzing the thermo-physical properties like thermal conductivity, thermal diffusivity and specific heat for the polymeric composit

The research deals with the collection of Allamah Ali al-Nuri’s guidance on readings, which he included in his book (Ghaith al-Naf’ fi al-Qira’at al-Sabe) and singled out it in a separate study,

    There is nothing new in saying that Baghdad is the capital of world culture for eight centuries during the Islamic caliphate, it was the Arab book manuscript and copied books worldwide touring most of the capitals of the world

أولاً: مشكلة البحث:

لاحظ الباحث عن طريق خبرته – المتواضعة- في أثناء عمله في ميدان التدريس في أقسام القرآن الكريم والتربية الإسلامية ان هناك ضعفاً في المستويات وتدنياً واضحاً في التفكير المنظومي للطلبة في مادة الإعجاز القرآني، ويرى الباحث أن هذا التدني يعود إلى أسباب عديدة من أبرزها: طرائق تدريس المادة، وغزارة المادة الدراسية، وصعوبة استيعابها في الوقت القصير المخصص لها، وان

The deviation from the rules and standards of the Arabic language is considered a melody, so the criteria were quantitative and temporal and be  deviate from the general rule  which are called abnormal and accept in time in the age of eloquence.

إمتاز ابن حجر بعلميته ، وغزارة عطائه في وضع كتب قيمة وتصانيف موسوعية  فكانت كتبه  هذه يشار لها  بالبنان .

اعتنى الكثير من  العلماء فاحتلت المرأة  مكانة متميزة  في كتبهم وخصصوا  لمعطياتها أجزاء واضحة ضمن مؤلفاتهم  ويعد أبن حجر أحد  هؤلاء العلماء الافذاذ الذين اعتنوا  بالمرأة  ، وهذا يعني انه أفرد لها جزءاً خاصاً بها سماه ( كتاب النساء) وهو يقع ضمن الجزء الرابع  من كتابه ، على الر

The poet dependent formation of a caupillary to stimuli ,sensory based on the areas of cognition in cluding raises every sense in the mind of therecipient , taking advantage of the senses which help him to perception and imagination and photography .i wanted in my Research that showed silent in the poetry of muslim Ibn al walid by the method of use the senses and then method of imaging divided the research to the axes according to topics hair began to praise ,I have found through mating poetic image with silent about the poet in the purpose of praise that he wanted . the caliphate of yazidI bnmazidknignt courageous , and thisis found in the clear signals in the poems silent poet what he wanting saying . The purpose that I choose to look out