Zerumbone is a well-known compound having anti-cancer, anti-ulcer, anti-inflammatory and anti-hyperglycemic effects. During its use for the disease treatment, the membrane of erythrocyte can be affected by consumption of this bioactive compound. The current study was the first report of investigation of the hemolytic activities on human erythrocytes and cytotoxic profile of zerumbone. The toxicity of zerumbone on human erythrocytes was determined by in vitro hemolytic assay. Brine shrimp lethality assay was used to evaluate the cytotoxic effect of zerumbone at concentrations 10, 100 and 1000 μg/mL. The human erythrocyte test showed no significant toxicity at low concentrations, whereas hemolytic effect was amplified up to 17.5 % at the highest concentration. The half lethal concentration (LC50) value of zerumbone against brine shrimp was less than 1000 µg /mL (LC50=190 µg/ml) showing the significant toxic nature of this compound. These results provide a baseline in terms of the toxicity of therapeutic formulations from this compound to membrane erythrocytes with a great attention to the highest concentrations, which paves promise for drug development.
The location element indispensable in the film, it is the container that meets the all the elements of the artwork, and place in the cinema topic or space as the existence of a material perceptible senses, is one of the key elements in the drama because he is one of the conditions to achieve supply drama which, with the nature of the vehicle because it is linked to reality the real and the reality of mental imagined, and returns the importance of the place mentally to change the pattern in the building's traditional place in the world of the film, is that the space under the facts of the events imagined or mental and determined by the processors directorial, and where mental in the movies but found himself a world with a pace sometimes s
... Show MoreCommunity peace is achieved in law-based states Constitutional institutions with competence and powers, and otherwise that peace is shaken and begins to collapse. The movement of individuals and groups in the State is regulated by law The law and its proper application without selectivity or exception, and then the sense of equal opportunity and equal rights grows every citizen looks at his spouse, what he has, and when he is unbalanced, a sense of frustration and stealing of rights is generated Societal peace suffers from the shocks of instability and what is reflected in the surrounding environment. Instead of production, demolition takes place, which impedes the achievement of the required peace.
... Show MoreThe research includes a bout IL- IQulle , and their role in scientific of the Islamic – Arabic civilization , for Dr. Khlood M.Namma the proff in the collage of education for woman , Baghdad university , History department .
The research aims to identify the role of educational institutions in instilling the values of integrity among emerging in word and deed and identifies research in educational institutions that have a significant impact in the emerging figures such as (family , school , media , mosque , civil society organizations , youth clubs .Have been identified the most important search terms of ( values ,educational institutions , Integrity) also touched search particular concern values education and its impact on emergent behavior , then separate search in the role of each educational institution to establish moral values in general and the values of integrity, particularly in the behavior of emerging
The Research aimed for identification the significant of health problems that occurrences through
misused of computer for those whom attaches with more than two hours daily and to identification the
nature of demographical characteristics variables and that related variables with using computer. Also to
know the level of user’s knowledge for some attaché’s equipment's and finally creating a new suggested
measurement scale for studying health problems that were occurred through misused of computer.
Creating questionnaire includes several domains (Social problems – family environment, Social problems –
external environment, some health problems attaches with related equipment's, psychological problems,
and hea
הקדמה
הריאליזם הספרותי במשמעו הכללי מצייג אשר כל מה מציינת בה הספרות מציורים מדוייקים לסביבה ולכן אדם. ויש להתחשב בפרטים המשותפים לחיים היומיומית.
האסכולה הריאליזטית מצטיינת בזיאנרים אין זוכים בם איזו אסכולה ספרותית אחרת. האסכולה הזאת הופיעה בספרות העברית החדשה כתוצאה להשפעתה של הספרות העברית בס
... Show MoreThe roots of international relations: peace or war: A critical review A great debate has taken place about international relations between scholars concerning peace and War .The concept of root is matched with that of exception. And the importance of the research lies in the ensuing results in the report about the legitimacy of war and the space it holds, so if the origin of international relation is war .the obstacles against it are going to decrease .and if the origin lies in peace then the dimension of its legitimacy will narrow. key words: international relation –peace-war. Résumé : L’Origine des relations internationales : guerre ou paix : révisions critiques L’origine des relations internationales entre guerre et paix, a s
... Show Moreشَهِدَت منطقة الخليج العربي والسَّاحِل العُماني تصاعد مُستوى الحِراك الشعبي، والمُطالبات بتحقيق الاِستقلال التام، وإنهاء الاِلتِزامات والاِرتِباطات الدولـيَّة سواء كانت في إطار الحِماية أو الاِستِشارة أو الصِّداقة، وأصبحت واجِهات ملحوظة من قِبل الفِئات المُـثـقَّـفة في بدايات العقد الثاني من القرن العشرين، وعبَّرت فيها القِوى الوطنيَّة عن حاجاتها في إجراء عملـيَّات التغيير والتحوّل الاِجتِماعي وعلى
... Show MoreThe science of exegesis was started by the first teacher, the Holy Prophet, and then further developed in various methods and approaches through history