Zerumbone is a well-known compound having anti-cancer, anti-ulcer, anti-inflammatory and anti-hyperglycemic effects. During its use for the disease treatment, the membrane of erythrocyte can be affected by consumption of this bioactive compound. The current study was the first report of investigation of the hemolytic activities on human erythrocytes and cytotoxic profile of zerumbone. The toxicity of zerumbone on human erythrocytes was determined by in vitro hemolytic assay. Brine shrimp lethality assay was used to evaluate the cytotoxic effect of zerumbone at concentrations 10, 100 and 1000 μg/mL. The human erythrocyte test showed no significant toxicity at low concentrations, whereas hemolytic effect was amplified up to 17.5 % at the highest concentration. The half lethal concentration (LC50) value of zerumbone against brine shrimp was less than 1000 µg /mL (LC50=190 µg/ml) showing the significant toxic nature of this compound. These results provide a baseline in terms of the toxicity of therapeutic formulations from this compound to membrane erythrocytes with a great attention to the highest concentrations, which paves promise for drug development.
The research paper talks about one of the topics that deals with one of the high-style styles in the Holy Qur’an that carries with it a high and influential style in directing the Qur’anic context, as the verses are singled out with certain words, each of which came out to other meanings, which is what was called in the past “what the wording agreed and the meaning differed Or the so-called “faces and analogues” and the meaning of analogues in the language and the Qur’an; To mention a word in a place and it means a meaning other than the other, and to interpret each word with a meaning other than the other meant by the faces, and accordingly the goal of the research is in the linguistic significance, in order to reveal the tr
... Show MoreAddresses current research to the subject of metaphor as a field important in the design of industrial product, so it was a problem search: Does industrial product which is designed mainly to reflect the principle of metaphor role in receiving, and how the application of mechanisms theory correct as stipulated in institutions metaphor properly for this orientation in achieving those metaphors. What are the relations of reciprocity that influenced the establishment of the design and construction of the system for industrial product, the objectives of the research were standing on the interactive nature of the relations between the metaphor and the process of industrial product design? And identify strengths and weaknesses in the processes
... Show MoreJean-Paul Sartre est la figure principale de l’existentialisme au XXe siècle et spécialement à partir des années cinquante. En partant du travail dans les lycées dans les années trente comme professeur de philosophie, passant par la guerre qui l’obligeait à rester comme témoin passif jusqu’à de l’après guerre avec la naissance de l’existentialisme, Sartre déploie tous ses efforts pour une référence intellectuelle majeure sur tous les fronts: littéraire, philosophique et politique. Dans tous ses livres Sartre aborde le statut de la littérature des idées et de l’écrivain dans la société. Il apparait comme un réactionnaire qui cherche à « régler ses comptes avec le milieu bourgeois dans leq
... Show MoreIf the syntactic structure is a reflection of what is in the mind of the creator of synergies
نالت الحياة الادبية في مملكة غرناطة الاندلسية حظاً كبيراً
تتسارع التحولات السياسية في العصر الحديث، وتتزايد التحديات التي تواجه المجتمعات، حيث يظهر التطرف كظاهرة تهدد أمن الدول واستقرارها، وتعد الإصلاحات السياسية خطوة حيوية نحو تحقيق تنمية مستدامة وتحقيق التوازن في المجتمعات. أذ يهدف هذا البحث إلى استكشاف وتحليل دور الأصلاح السياسي كآلية فعالة في مكافحة ظاهرة التطرف. وطالما أن الدول في المنطقة العربية تعاني من التسلط والأستبداد وغياب دور المؤسسات السياسية الفعل
... Show MoreThe aesthetic dimension in popular subjects is one of the important topics in the history and culture of peoples, as it is the vessel from which their faith, traditions, original values, language, ideas, practices and way of life are derived, which expresses their culture and national identity, and it is the bridge of communication between generations throughout the ages.
It is one of the main pillars in the process of development and development, and popular subjects have special images related to real daily life, and they are the best source for man to narrate through him in his portrayal of daily life in general, and for the artist in particular, who is part of this daily life and its vocabulary, as he interacts with it so that
... Show Moreنشأ الانسان منذ بدأ الخليقة محباً للجمال بما يراه من حوله في الطبيعة وكان حريصاً على تزيين نفسه ومنزله بجلود الحيوانات أذ كان السجاد في مراحله الأولى بدائية حتى بلغت الذورة عندما أكتسى السجاد خملة زادته فائدة بأن جعلته أكثر مقاومة وأكثر حفظاً للدفء (الجبوري،2001 ، ص10)وأن التطور الهائل في العلم في هذه السنوات أدى الى أستخدام الكثير من المنتجات والوسائل التي سهلت على الأنسان الكثير من أمور حياته (العبود،2008،ص12) “
... Show Moreإن أهميـة بحثنـا تتضـح مـن خـلال التطـرق إلى دراسـة المـذهب العسـكري في حقبـة الاتحـاد السـوفيتي السـابق وإبـراز الجوانـب الرئيسـة المتعلقـة بفلسـفة المـذهب العسـكري السـوفيتي ومضـامينه الاستراتيجية مــن جانــب، وفلســفة المــذهب العســكري الروســي لمرحلــة مــا بعــد الحــرب البــاردة والتغـيرات المهمـة الـتي طـرأت عليـه، ممـا أفـرز لنـا بطبيعـة الحـال مضـامين مـذهب عسـكري روسـي جديــد قــد يتقــا
... Show MoreThe Iraqi outfit is characterized by special features and identity that are closely related to the traditions, customs, religious and social beliefs and other references of the Iraqi environment and its factors affecting the individual and society. Every place in Iraq has its own uniform, which differs in terms of its artistic, aesthetic and functional components from place to place.
The abaya, especially worn by women, is especially distinct in terms of the design of the uniform, the nature of the cloth made of it, as well as the color of the abaya, which is dominated by black in most designs. The Dar Al-Taros Center and Textile Research initiated the construction of theoretical and practical bases in the design of contemporary
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