Breast cancer is the most prevalent malignancy among women worldwide, in Iraq it ranks the first among the population and the leading cause of cancer related female mortality. This study is designed to investigate the correlations between serum and tissue markers in order to clarify their role in progression or regression breast cancer. Tumor Markers are groups of substances, mainly proteins, produced from cancer cell or from other cells in the body in response to tumor. The study was carried out from April 2018 to April 2019 with total number of 60 breast cancer women. The blood samples were collected from breast cancer women in postoperative and pretherapeutic who attended teaching oncology hospital of the medical city in Baghdad and the serum markers evaluated by ELISA technique are Carbohydrate Antigen 15-3 (Ca 15-3), Carbohydrate Antigen 27.29 (Ca 27.29), Anti-Mullerian Hormone (AMH), Tumor Necrosis Factor-Alpha (TNF-α), Interleukin-6 (IL-6), Interleukin-10 (IL-10) and Human Epidiymis Protein-4 (HE4). Tissue samples were collected for the same breast cancer women who attended medical city, Baghdad with total number 30. The tissue markers evaluated by Immunohistochemical technique are Estrogen Receptor (ER), Progesterone Receptor (PR), Human Epidermal Growth Factor Receptor 2 (Her 2/neu) and Cyclin E. The results showed a positive significant correlation (p = 0.017) between Ca 27.29 and Her-2/neu, (p = 0.038) between IL-6 and cyclin E phenotype, (p = 0.051) between TNF-α and Cyclin E intensity, (p = 0.005) between HE4 and Her-2/neu, and negative significant correlation (p = 0.058) between IL-10 and ER score and (p = 0.045) between HE4 with Cyclin E intensity. We conclude from these correlations that positive correlations increasing disease progression, like correlation between Ca 27.29 and Her-2/neu, cyclin E with IL-6 and cyclin E with TNF-α. And the negative correlations may contribute to delay disease, like correlation between IL-10 and ER. From the correlations results in this study, it is clear that the Ca 27.29, Her-2 / neu, cyclin E markers play an important role in disease progression.
The impact of management control systems (MCS) on organizations performance empirical research has been the subject of numerous studies during the past decade in developed and emerging economies. In the contemporary competitive, complex and changing global business environment, firms are being challenged to adopt business models that enable them to address the strategic uncertainties and risks they face in their business environments. The main issue of this study is that management accounting researchers argue that one of the ways firms can continually rejuvenate themselves to survive and succeed in these complex and uncertain environments is to understand the role of management control systems in Formulating a b
... Show Moreالفلسفة السياسية وفلاسفتها دراسة في فكر الفيلسوف ليو شتراوس
God bestowed upon the Imams of the Ahl al-Bayt (peace be upon them) knowledge and wisdom, in addition to give them virtue as long as it was not given to anyone from the worlds. knowledge have been enriched from them that cause pride.
Islam is a religion that God wanted to be a platform emerges from human steps in various walks of devotional and economic life, etc, so it went Islam, guids human beings being as successor of God on earth.
The result that the worship of man for the Lord, which is one of the reconstruction of the land that is the secret of the sustainability of human life on the ground, often urged the Sunnah on the reconstruction of the earth and the importance of planting them and paired the reconstruction work that obtained by the human reward which would Allah his home in the Hereafter, There construction of the earth does not involve just planting them; it takes many forms Maintaining them and not marring the form of reconstruction and
... Show MoreGod Almighty sent down the Noble Qur’an to guide people in all areas of their lives, including the field of functional business.
Praise be to God, Lord of the Worlds, and prayers and peace be upon our master and beloved Muhammad and all his family and companions. As for what follows:
Advantage of the science of management for a lot of other sciences vitality and openness to the rest of the science and knowledge of the various branches fields, and at the same time, overlapping and intermingling majora between the various branches of administration and specialties, and based on this fact, the idea of this research to come out of one of the important topics with two topics of vital in the field of strategic management, namely patterns Strategic Command, and the effectiveness of senior management teams. I've seen the science of management, particularly in the field of strategic management, large shifts and changes, especially in the last two decades, as the RPR Strategic Management rich field of research and the emergenc
... Show MoreThere was a huge role in the history of a muslim woman and several books have mentioned that politically or in religion and even scientifically and socially which leaded a lot of women to look up to these women who helped in keeping the religion just in the right form for other generations
This research deals with the ideas of Imam Muhammad bin Al-Waleed bin Khalaf bin Sulaiman bin Ayyub , Al -Qurashi, The Moroccan, The Andalusian, Al-Maliki. He was known as Abu Bakr Al-Tartoushey , where thesis deals with the details of his personal life and as well as his scientific path as well as his works, and also covered the views of jurisprudence in the personal status and especially on the subject of divorce and inheritance,
The government gave the muslims additional things to the sum of money ,it was al rizq which was given to the mujahidin .
Those who distributed the ata where called al urafa ,they were from the best biography people