Breast cancer is the most prevalent malignancy among women worldwide, in Iraq it ranks the first among the population and the leading cause of cancer related female mortality. This study is designed to investigate the correlations between serum and tissue markers in order to clarify their role in progression or regression breast cancer. Tumor Markers are groups of substances, mainly proteins, produced from cancer cell or from other cells in the body in response to tumor. The study was carried out from April 2018 to April 2019 with total number of 60 breast cancer women. The blood samples were collected from breast cancer women in postoperative and pretherapeutic who attended teaching oncology hospital of the medical city in Baghdad and the serum markers evaluated by ELISA technique are Carbohydrate Antigen 15-3 (Ca 15-3), Carbohydrate Antigen 27.29 (Ca 27.29), Anti-Mullerian Hormone (AMH), Tumor Necrosis Factor-Alpha (TNF-α), Interleukin-6 (IL-6), Interleukin-10 (IL-10) and Human Epidiymis Protein-4 (HE4). Tissue samples were collected for the same breast cancer women who attended medical city, Baghdad with total number 30. The tissue markers evaluated by Immunohistochemical technique are Estrogen Receptor (ER), Progesterone Receptor (PR), Human Epidermal Growth Factor Receptor 2 (Her 2/neu) and Cyclin E. The results showed a positive significant correlation (p = 0.017) between Ca 27.29 and Her-2/neu, (p = 0.038) between IL-6 and cyclin E phenotype, (p = 0.051) between TNF-α and Cyclin E intensity, (p = 0.005) between HE4 and Her-2/neu, and negative significant correlation (p = 0.058) between IL-10 and ER score and (p = 0.045) between HE4 with Cyclin E intensity. We conclude from these correlations that positive correlations increasing disease progression, like correlation between Ca 27.29 and Her-2/neu, cyclin E with IL-6 and cyclin E with TNF-α. And the negative correlations may contribute to delay disease, like correlation between IL-10 and ER. From the correlations results in this study, it is clear that the Ca 27.29, Her-2 / neu, cyclin E markers play an important role in disease progression.
يهدف البحث إلى تحليل خطوات التكلفة المس تهدفة الخضراء من أجل تخفيض تكاليف الفشل البيئية المتمثلة بالتكاليف الداخلية والخارجية للشركات الصناعية وجعل منتجاتها صديقة للبيئة وذات ضرر قليل من خلال تخضير المنتجات والتي تؤدي إلى تخفيض تكاليف الفشل البيئية
Abstract The Kenyan policy towards Somalia was influenced by a set of interrelated factors between the two countries and stemmed from the internal environment and most prominent: the geographical factor, ethnic, cultural, religious, political, economic and security, has been dominated by this policy since independence from the British colonial administration in the sixties of the last century and so far the nature of instability and tension, As the two countries are geographically contiguous and as security risks escalate, Kenya in 2011 rushed military action against Somalia, the first military action by Kenya outside its borders since independence.
يعد الأمن البيئي موضوعاً حيوياً لا سيما في العصر الحديث، حيث بدأت تحديات التغير المناخي تتدهور وبسرعة متزايدة. وتزداد أهمية هذا الموضوع مع تصاعد تلك التحديات، أذ يتعين على الجميع لا سيما النساء منهم المشاركة في الحفاظ على البيئة لضمان استدامتها للأجيال الحالية والمستقبلية. ويُعد الحفاظ على البيئة والموارد الطبيعية أمراً ضرورياً لضمان استدامة الكوكب ومستقبل الأجيال القادمة. وفي هذا السياق، يأتي دور المرأة
... Show Moreتم ت داول مصطلح الأزمة ا دلولية في السياسية ا دلولية خال القرن التاسع عش ر لتحدي دا ملدة الانتقالية بين السلم والحرب سواء أ دت الأزمة إلى نشوب صراع مسلح أم مت ت ت سويتها بالطرق السلمية، وتع دالأزمة ا دلولية مرحلة مت هيدية ل لحرب وهي ا رملحلة التي يسعى فيها أ طرا فالأزمة إلى إبعاد احتمالية نشوء أ و اندلاع الحرب، فالأزمة ه ي مدة حرجة ومرحلة خطيرة بين وقتي السلم والحرب، إن العلاقات ا دلولية تكاد ت عيشأ زمات متلاحقة ع
... Show MoreOf good reasoning (the art of unique moral turn him poets of Andalusia in
poetry verse emitter myself, and to achieve a very technical. Either the emitter is
related to the nature of the environment and the composition of personal Andalusia
of appetite for life and interaction with the legibility beautiful, and it was (wit)
feature in them even said they are charming as Bagdad ions , and either art, it made
them this color to show their ability intellectual in the search for bugs, and
stimulate their imaginations in a contract equations in the interpretation and find
justifications for the ideas and meanings Exaggeratedly times, and especially in the
purpose of praise, and novelty in many cases, as in the spinning
The povety in a subjct of one of the most important problems that
accompanied the development process in iraq and is now pointing in the
depth of institutional struetues and threaten the sociol fabric and cohesion
mechamisms .
The study included of the most importana social problems that
accompamied thecrises and occupation in iraq as aproblem of unemployment
aworce, forced displacement and disintegration of family and juvenile
delinguency and the problems of drug addiction .
The study relied on sample slected from the city of Baghdad ,showed
the most important results of that two-thirds of the asssets of an urban sample
compared to one third of them from rural aelcyrounds and that there is
arelationship
مثل الوعي الطبقي اعلى مراحله لدى الفكر الماركسي الحديث عند كل من ماركس وانجلز ولينين ليس مجرد انعكاس للواقع وانما يكون بصورة جدلية من خلال انعكاس الوعي على الواقع واعادة انتاجه فبعد ان كان الوعي هو نتاج تطور الواقع اصبح اداة في تطوير الواقع، أي تأثير البنى الفوقية على البنى التحتية( المادية التاريخية) بعكس ما دعى اليه ماركس، اذ أعطى لينين للوعي دوراً كبيرا في التطور التاريخي، وعد الوعي الطبقي هو الاداة التي
... Show MoreIn this study, the researcher aimed to define and measure the relevance and effect of the governmental organizations in complying with Iraqi Ministry of Transportation's requirements towards achieving the social responsibility, embodied in the ten commandments of the United Nations Findings displayed the availability of realization regarding organization managers towards social responsibility with their various capabilities and tendencies in relation with the representing entries of those Ten Commandments.The study showed the relation between the effectiveness of those organizations and dimensions of the ten commandments of social responsibility, with the existence of a significant effect for the said effectiveness on achiev
... Show Moreتكمن مشكلة البحث بان المؤسسات عامةـ والتعليمية منها خاصةفي الوقت الحاضرتواجه ظروف بيئيةتفرض عليها حتمية التغيير ، وذلك بسبب التحولاتالتي تحدثفي عالمناالحالي سواءًكان على المستوىالمحلي أو العالمي أو على المستوىالمؤسسة نفسها مما يجعلمؤسساتنا التربويةبحاجةملحةلمواجهة هذا التغيير القادم وذلك من خلال معالجةالمشكلاتالتي قد تظهر بطرق مبتكرة وابداعية مغايرةللطرقالتقليدية ،وذلك من خلال تهيئة المناخ الت
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