Metalloendopptidase MEP
cystatin C
diabetic nephropathy (DN)
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Metalloendo peptidase is a neutral endopeptidase that cleaves
peptides at the amino side of hydrophobic residues and
inactivates several peptide hormones, including atrial natriuretic
factor, giucagon, enkephalin, substance p, neurotensin, oxytocin,
and bradykinin. It is also a major enzyme for the degradation of
beta-amyloid. This study aimed to measure enzyme activity and
compare it with other biochemical changes in sera patients with
diabetic nephropathy. The study included 35 pathological
samples of people with diabetic nephropathy, 24 samples from
males and 11 samples from females, as well as the same number
of healthy people as a comparison group of 15 males, 20 females,
with the ages of both groups of patients with diabetic
nephropat
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