The interleukin-1 family has multifaceted roles in men٫s reproductive syste. Out of these is interleukin-1 receptor antagonist (IL-1RN) which exists in men gonads, and in case of infection and inflammatory process, its activity is increased. The current study aims to verify a possible linkage of Variable Number Tandem Repeat (VNTR) polymorphism of the IL-1RN gene with human men infertility. The study groups enrolled included 100 infertile men and 100 fertile and healthy men. Their seminal fluids were subjected to analysis. Also peripheral blood samples were collected for the assessment or detection of polymorphic Variable Number Tandem Repeats (VNTR) polymorphism of interleukin-1 receptor antagonist gene (IL-1RN). Two alleles, namely IL-1RN1 allele corresponding to 410bp fragment and IL-11RN2 that corresponding to 240bp fragments, are a marker for human men infertility, detected by PCR technique. The results delineated a high frequency of IL-1RN2 allelic gene variants (26%), and two VNTR allelic gene variants carriers IL-1RN1 and IL-1RN2 (16%) among infertile men with significant impacts on sperm motility and morphology (P< 0.000-0.002) respectively. This prospective study inKurdistan region (Erbil –Iraq) defined a significant impact of VNTR polymorphism of IL-1RN gene in the etiology of men infertility especially on sperm motility and morphology; particularly carriers of IL-1RN2 allelic variants
Aim: To determine the expression of tissue inhibitors of metalloproteinases (TIMP-2) in oral squamous cell carcinoma (OSCC) and the difference in its expression level between positive and negative HPV-16 (human papilloma virus- 16) OSCC patients. Methods: This study was conducted on 33 biopsies obtained from patients with OSCC and 10 normal oral mucosa as controls. In situ hybridization (ISH) was used to investigate the presence of HPV-16, while immunohistochemistry (IHC) was used to estimate the expression level of TIMP-2. Results: The TIMP-2 was expressed in 27 (81.8%) of OSCC sections with no significant difference between its expression level in HPV-16 positive and HPV-16 negative OSCC cases (p=0.058). TIMP-2 was found to be hig
... Show MoreModern linguistic theories have given the researchers some real opportunities to find out important linguistic phenomena that
Hegel's book entitled"The science of Beauty" is a serious attempt to establish a foundationfor this science. Hegel decided from the beginning, that his research is limited to artistic beauty more than natural beauty. He regards artistic beauty above the natural beauty as the former is the product of the soul.
Everything that comes from the soul is superior to what is found in nature and the worst idea that penetrates human's thoughtbetter than any product of the nature. Man turned to art as a means of his awareness of his superior soul and his interests. All nations poured their highest outputs of their perceptions in the product of art.
... Show MorePraise be to God, Lord of the worlds, and prayers and peace be upon our master Muhammad and upon his family and companions as a whole.
The topic of attention was drawn to the attention of the speakers, as it made me ponder it carefully, and my goal in that is to know the reason for the interest of the speakers and their care for it, and to clarify from their books the purpose of making this topic one of the advanced investigations with them.
The idea of writing a paper on the subject of consideration was not absent from my thinking, because I saw the attention of speakers on this issue, as they made it one of the first issues that they deal with studying in their work
... Show MoreAl-Jahiz was an aesthetic philosopher, and the concept of beauty for Al-Jahiz depended on objectivity and focus on the idea of moderation
تعد فرقة المعتزلة من الفرق الإسلامية الكبيرة التي شغلت حيزاً كبيراً في التاريخ الإسلامي, فقد ظهرت المعتزلة كفرقة ذات نسق عقيدي مميز الى الوجود في العصر الأموي , ولكنها شغلت الفكر الإسلامي في العصر العباسي عندما بلغت أوج قوتها ردحاً طويلاً من الزمن .
The Islamic thought still suffers from the problems posed by Western thought in the modern era, especially after the establishment of the modern Arab state, and replacing the intellectual reference that prevailed at that time, which is represented by Islamic thought with another intellectual reference represented by Western thought. Since then, thinkers and innovators and reformers and intellectuals of the Islamists, Are trying to get out of these many problems and multiple, after imposing the nature of that thought and those references with all their consequences, and one of these problems that is still Islamic thought suffers, the bilateral problem that some academics have raisedThe title of the symposium failed The Islamic thought and
... Show MoreThrough the title of the research, it is clear that beliefs in different religions are considered the important principles that distinguish religions, sects, and sects from each other, and belief is the important foundation and pillar on which the individual and society is based, because God Almighty called for reflection and reflection to choose his peaceful belief away from blind imitation. It is (belief in the existence of God, and His unification - and glorifying His attributes - and belief in the prophets in general, and belief in the angels in general, and in the revealed books in general).
Praise be to God, Lord of the worlds, and prayers and peace be upon the master of the messengers, his family and all his companions. And after:
This research talks about a topic that has taken a great deal of attention and controversy among many Arabic language scholars, which is the subject of poetic necessity, but it does not talk about the necessity in general, but one of the scholars and writers who had stances and references to this issue was chosen in many places from their books. Abu Al-Ala 'Al-Maari was among the scholars who dealt with this issue on numerous occasions and occasions, and this was evident in his books.
We chose this topic to see how Abu Al-Ala
... Show Moreاثناء تفاعل الديزنة تكونت صبغة أزو جديدة عن طريق تفاعل 3-امينوفينول مع 2,4,6-ثلاثي هيدروكسي اسيتوفينون . ثم تم تفاعل هذا الليكاند مع بعض ايونات العناصر الكروم والحديد الروديوم والروثينيوم بتكفؤهم الثلاثي والكوبلت الثنائي والموليبدينوم سداسي التكافؤ مكونة معقدات فلزية مختلفة بأشكال هندسية متعددة. تم ملاحظة تناسق مجموعة الازو مع ايونات العناصر من خلال ملاحظة ظهور حزم امتصاص الفلز مع النتروجين والاوكسجين ب
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