Hepatitis, a condition of liver’s inflammation that can be self-limiting or, in certain chances, it may lead to liver cancer, fibrosis or cirrhosis. Hepatitis viruses mainly cause hepatitis in the world. People with hepatitis C have predominant chances to develop diabetes as HCV virus participates in causing type 2 diabetes. HCV virus causes pathogenesis in two ways: it either directly destroys the β cells of pancreas or contributes to the specific autoimmunity of β cells. The present cross sectional study was done in Wazirabad Tahsil of Gujranwala District to analyze the percentage of patients suffering from hepatitis C who had the risk of diabetes mellitus. For this research work, demographic information and data about any other medical history were collected by using a questionnaire. Blood samples were collected from hospital and real time PCR was performed to measure the viral load and blood sugar was measured by using glucometer. Data were then analyzed by using statistically designed software. A total of 29.33% patients, having hepatitis C, were found to be diabetic in Tehsil Wazirabad. 14.70% male and 38.59% female patients having hepatitis C were diabetic. From results shown that the patients of hepatitis C are at higher risk to develop diabetes, therefore; it is supposed that persons having hepatitis C should regularly visit doctors for routine check-up of diabetes and change their life style to reduce the risk of developing diabetes.
Interleukin-35 (IL-35) is a new member of IL-12 family of cytokines, and its role in pathogenesis of hepatitis B virus (HBV) infection has been recently suggested. Accordingly, a case-control study was conducted during June - October 2018 to determine IL-35 serum level in Iraqi patients with chronic HBV infection. The results revealed that IL-35 level was significantly decreased in patients as compared to control (163 vs. 301 pg/ml; p < 0.001). However, such decreased level was more pronounced in patients at the age groups < 40 and 40 – 50 years (165 and 145 pg/ml, respectively) as compared to the corresponding age groups in control (482 and 234 pg/ml, respectively). In the case of gender groups, both male
... Show MoreBackground: Immunoassays are one of the oldest techniques used in diagnostic virology where a number of serologic techniques, with different degrees of sensitivity and specificity, for the detection of HCV antigens and their specific antibodies, have been developed.
Materials and methods: One hundred and four sera samples were collected from National Center for Blood Transfusion, Gastroenterology and Liver Diseases Hospital, Central Public Health Laboratories and Teaching Laboratories. According to the manufacturers practical instructions, many available methods for detecting Anti-HCV antibodies, including enzyme linked immunosorbent assay (ELISA), immunochromatographic assay (ICA), recombinant immunoblot
Rheumatoid arthritis (RA), is an autoimmune, and inflammatory disease that is closely related to the destruction of cartilage and bone. DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. Recent evidence has demonstrated that DC-SIGN is involved in the pathophysiological of chronic inflammation, so DC-SIGN has been linked to several autoimmune and may play an essential indicator in the pathogenesis and progression of RA. Therefore, the purpose of this study is to determine the serum level of DC-SIGN in RA patients, as well as the level of DC
... Show MoreBackground: Many workers have described the prevalence of HBV markers and anti-HCV among selected populations including health care personnel in Iraq. The purpose of this study is to describe the demographic characteristics and risk factors of hepatitis B and C in a sample of Iraqi health care workers (HCWs).
Materials and methods: A total of 1656 HCWs selected from Baghdad city was included in this study. A questionnaire form was filled for each HCW by direct interview. The data requested
included demographic characteristics and risk factors of exposure to HBV and HCV. HCWs were screened for the presence of HBsAg, anti-HBs and anti-HCV.
Results: A higher prevalence of HBsAg, anti-HBs and anti-HCV was de
Back ground: Oxidative damage has been suggested to play a key role in accelerating inflammation and to be involved in the pathogenesis of rheumatoid arthritis (RA) and
osteoarthritis (OA). Many studies had shown that those patients have low antioxidants level and are at risk of increased oxidative stress.
Objective: This study was designed to examine the levels of serum Total Antioxidant Status (TAS). Malondialdehyde (MDA) as index of lipid peroxidation and C–Reactive Protein (CRP) as a
marker of oxidative stress in patients with RA and OA and compared them with healthy control.
Method: Serum TAS , MDA and CRP levels were measured in 16 RA and 24 OA patients and compare with those obtained from 25 healt
Hepatitis B is an inflammation of the liver that caused by Hepatitis B virus (HBV) which is DNA virus that infects the human and some kinds of animals such as chimpanzees and birds. This disease considered as the major disease of mankind and a serious global public health problem. HBsAg, HBeAg, HBcAb, HBeAb and HBsAb are markers used to detect the presence and the stage of infection. The current study included (181) individuals from both sexes, (137) males and (44) females. By ratio 3.11: 1.The mean age of patients 2.4033 ± 0.83519 (range 18-73) years as follows < 20 (11.6%), 21–40 (47.5%), 41–60 (29.8%) and > 60 (11.0%) . These patients are 73 (40.4%) Blood donors from Central Blood Bank, 88 (48.6%) Chronic kidney failure at Ibn –
... Show MoreObjective(s): To Evaluate Diabetes self –management among patients in Baghdad City and to compare
between these patients self-management relative to the type of the disease.
Methodology: A descriptive design was conducted in Baghdad city, started from November 16th 2017 to the
end of May 17 th 2018 in order to evaluate Diabetes self-management. Purposive (non-probability) sample,
which was consisted of (120) patients who were diagnosed with D.M. The sample is comprised of (60) patient
with diabetes type I and (60) patient with diabetes type II. It is consisted of (60) male and (60) female. A
questionnaire is constructed for the purpose of the study. It is composed of (42) items. Reliability and validity of
the ques
Background: Diabetes mellitus is a common health problem of the world. Iron may be a part of the cause of the disease and its Complications
Objectives: This study was designed to determine the relationship between the levels of iron indices and diabetes mellitus type 2. Type 2
Type of the study: Cross –sectional study.
Methods: diabetes mellitus is clinical condition characterized by hyperglycemia due to the absolute or relative deficiency of insulin. It is also followed by pathological abnormalities like impaired insulin secretion, peripheral insulin resistance, and excessive hepatic glucose production. Although type 2 diabetes mellitus i
... Show MoreCox regression model have been used to estimate proportion hazard model for patients with hepatitis disease recorded in Gastrointestinal and Hepatic diseases Hospital in Iraq for (2002 -2005). Data consists of (age, gender, survival time terminal stat). A Kaplan-Meier method has been applied to estimate survival function and hazerd function.
Background: Cervical spondylotic myelopathy (CSM) is considered the most serious consequence of cervical spondylosis and accounts for the majority of non_traumatic paraparesis and/or quadriparesis. The electrical property of the spinal cord and its susceptibility to injuries renders electrophysiology relevant to the management of CSM. Somatosensory evoked potentials study (SEPs) is an objective assessment of the functional integrity of the neural pathway.
Objective: Utilizing both of the median and the posterior tibial SEPs in evaluating the functional integrity of the cervical spinal cord in patients with CSM and to correlate the SEPs findings with the clinical and MRI findings.
Patients and methods: Twenty two patients with CSM (