Preferred Language
Articles
/
bsj-3072
In Silico Analysis of Regulatory Elements of the Vitamin D Receptor
...Show More Authors

Vitamin D receptor (VDR) is a nuclear transcription factor that controls gene expression. Its impaired expression was found to be related to different diseases. VDR also acts as a regulator of different pathways including differentiation, inflammation, calcium and phosphate absorption, etc. but there is no sufficient knowledge about the regulation of the gene itself. Therefore, a better understanding of the genetic and epigenetic factors regulating the VDR may facilitate the improvement of strategies for the prevention and treatment of diseases associated with dysregulation of VDR. In the present investigation, a set of databases and methods were used to identify putative functional elements in the VDR locus. Histone modifications, CpG Islands, epigenetic marks at VDR locus were indicated. In addition, repeated sequences, enhancers, insulators, transcription factor binding sites and targets of the VDR gene, as well as protein-protein interactions with bioinformatics tools, were reported. Some of these genetic elements had overlapped with CpG Islands. These results revealed important new insight into the molecular mechanisms of the VDR gene regulation in human cells and tissues.

Scopus Clarivate Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Wed Jan 01 2014
Journal Name
Journal Of The College Of Languages (jcl)
سةرهةلَداني رِؤذنامةنووسيي كوردي و رِؤلَي لة ثةرةسةندني زمان و ئةدةبدا
...Show More Authors

Appearance of the Kurdish press in the Kurdish literature was affected by as set of both external and internal factors. The former was realized in the spreading of press and publications especially at the neighboring countries in the second half of the 19th century. The latter factors, external ones ,were concerned the political situations undergone by the Kurdish people who severely suffered injustice practiced by the Othman authority .All these reasons had driven the educated to migrate to search for more safe places to practice their cultural actions with absolute freedom. Consequently, the first newspaper was issued on 22/4/1898 in Cairo which pointed the birth of the Kurdish press inside and outside Kurdistan region which

... Show More
View Publication Preview PDF
Publication Date
Tue Oct 05 2021
Journal Name
Arab Science Heritage Journal
مظاهر الترف في الوظائف ابان العصر الفاطمي
...Show More Authors

The Fatimids were arguing with the Abbasids in everything, even in the causes of civilization, and the Islamic moderization had matured,

View Publication Preview PDF
Crossref
Publication Date
Sun Jul 02 2006
Journal Name
Political Sciences Journal
السياسة الامريكية وحركة الاصلاح السياسي في السودان
...Show More Authors

السياسة الامريكية وحركة الاصلاح السياسي في السودان

View Publication Preview PDF
Crossref
Publication Date
Sun Apr 01 2007
Journal Name
Journal Of Educational And Psychological Researches
( دور التخطيط في تنمية وتطوير المؤسسات التعليمية)
...Show More Authors

الأهمية :

التخطيط بالمعنى العام مارسته بعض الجماعات ، وكثير من الأفراد عبر العصور فهم حاولوا أو يحاولون التحكم في مستقبل حياتهم أو حياة أبنائهم ، وقد حدثنا التأريخ عن بعض التجارب لمواجهة الأزمات والكوارث التي هددت بعض الشعوب ، ولعل قضية سيدنا يوسف عليه السلام وهي تشير الى خطته لمواجهة المجاعة المنتظرة ، ومقوماتها حسن التخزين وضبط الأستهلاك وفترتها الزمنية ، فضلاً عن أمثلة تاريخية لموا

... Show More
View Publication Preview PDF
Publication Date
Sun Apr 01 2007
Journal Name
Journal Of Educational And Psychological Researches
مراحل التعليم ونظام التهذيب في جمهورية افلاطون
...Show More Authors

يحتل افلاطون (427-327 ق.م) المكانة الاولى بين الفلاسفة والمفكرين والمربين على امتداد تاريخ البشرية ، ويعد بعض الباحثين كتابه الشهير(الجمهورية) كتاباً في التربية والتعليم قبل ان يكون كتاباً في الاخلاق والسياسة ، فهذا الكتاب – المحاورة ضم بين دفتيه أجوبة على الكثير من الاسئلة التربوية والتعليمية عوضاً عن مضامينه الاخلاقية والسياسية والمعرفية والنفسية ، التي ساقها افلاطون باسلوب ادبي متين على شكل محاورة طو

... Show More
View Publication Preview PDF
Publication Date
Tue Dec 28 2021
Journal Name
Arab Science Heritage Journal
التراث العماري في ناحية بامَرني (دراسة ميدانية)
...Show More Authors

  The historical documentation of the architectural archeology has a fundamental and great importance in evaluating the architectural product that has suffered from neglect

View Publication Preview PDF
Crossref
Publication Date
Mon Oct 22 2018
Journal Name
Arab Science Heritage Journal
الرياضة الرياضة في الاندلس (ركوب الخيل انموذجا)
...Show More Authors

              Riding in Andalusia was a sport emphasized by Islam. It also works to strengthen the muscles, prevent them from sagging, gain vitality and vitality, regulate blood circulation and improve brain and heart function. The research we discussed in the study is not limited to a particular class. Most Andalusian rulers practiced equestrian And they hold concerts and competitions of horse competition, as happened during the reign of Caliph al-Hakam al-Mustansir and Muzaffar ibn Abi Amer and the governor adopted Ben Abbad and the Caliph Muhammad bin Bani al-Ahmar, the governor of the city of Granada in the presence of the great poets such as the son of Abu Salt and Ibn

... Show More
View Publication Preview PDF
Publication Date
Wed Oct 01 2008
Journal Name
Journal Of Educational And Psychological Researches
العنف ضد المرأةدراسة ميدانية في مدينة بغداد
...Show More Authors

      لطالما تحاشينا الخوض في الحديث عن المرأة , وكل ما يتعلق بها من موضوعات , خصوصا في سياق ما يطرح حولها من أمور كأنها لاتخص غيرها مثل : " الحرية "   "والمساواة "  " والحقوق " ... وغيرها من المواضيع التي تعج بها الكتب والشاشات والبرامج والمؤتمرات والندوات , التي غالبا ما ترفع فيها الشعارات المؤدلجة وتوضع اخرى , في أتون محموم , إن دل على شيئ فانه يدل بالدرجة الاولى عن مدى الفوضى الفكرية التي نعي

... Show More
View Publication Preview PDF
Publication Date
Mon Dec 01 2008
Journal Name
Journal Of Economics And Administrative Sciences
خطة الصيانة الوقائية ومحاكاتها على وفق معايير هندسة المعولية دراسة حالة في الشركة العامة للصناعات الجلدية - معمل رقم 7-
...Show More Authors

This research is an attempt to study and evaluate the maintenance function at Factory 7 - The State General Company for Leather Industries, and to design a computerized preventive maintenance system to design and to analyze preventive  maintenance.  To accomplish the objectives of this research, data were gathered and analyzed according to the reliability engineering criteria for the period 2/1– 30/6/2005, then a preventive maintenance plan was designed for each machine of the sample study using the computerized system designed in this research. A Monte Carlo Simulation methodology was used for the purpose of evaluating the performance of the preventive maintenance plan of each machine for one year. The simulation res

... Show More
View Publication Preview PDF
Crossref
Publication Date
Tue Jan 01 2013
Journal Name
Ibn Al-haitham Jour. For Pure & Appl. Sci.
Synthesis and Spectroscopic of Some new Metal Ions Complexes's with [N-(4-Methoxy Benzoyl Amino)-Thioxo Methyl] Leucine
...Show More Authors

A new ligand [N-(4-methoxy benzoyl amino)-thioxo methyl ] leucine (MBL) was prepared from the reaction of (4-methoxy benzoyl isothiocyanate with leucine acid in molar ratio (l:l), it was characterized by elemental analysis (C.H.N.S), FT-IR, UV-Vis, 1H and 13C-NMR. The complexes of the bivalent ions (Mn, Fe, Co, Ni, Cu, Zn, Cd and Hg ) have been prepared and characterized too. The structural was established by elemental analysis (C.H.N.S), FT-IR, UV-Vis spectra, conductivity measurements atomic absorption and magnetic susceptibility and determination of molar ration (M:L). The complexes showed characteristic behavior of tetrahedral geometry around the metal ions except with (Cu) complex showed square planer.