The target of this study was to synthesize several new Ciprofloxacin drug analogs by providing a nucleophilic substitution procedure that provides new functionality at the carboxylic group location. The analogs were synthesized, designed, and characterized by ¹HNMR, and FTIR. The synthetic path began from the reaction of ciprofloxacin drug with morpholine to give compound[B], ciprofloxacin derivative was linked with a variety of primary and secondary amines to give compounds[B1-B9]. The above-mentioned prepared compounds [B3 and B5] were applied to liver enzymes, and the increase in the activity of these enzymes was observed. In addition, a theoretical study was conducted to study the energies and properties of the prepared co

A Ligand (ECA) methyl 2-((1-cyano-2-ethoxy-2-oxoethyl)diazenyl)benzoate with metals of (Co²⁺, Ni²⁺, Cu²⁺) were prepared and characterization using H-NMR, atomic absorption spectroscopy, ultra violet (UV) visible, magnetic moments measurements, bioactivity, and Molar conductivity measurements in soluble ethanol. Complexes have been prepared using a general formula which was suggested as [M (ECA)₂] Cl₂, where M = (Cobalt(II), Nickel(II) and Copper(II), the geometry shape of the complexes is octahedral.

A series of Schiff base-bearing salicylaldehyde moiety compounds (1-4) had been designed, synthesized, subjected to insilico ADMET prediction, molecular docking, characterization by FT-IR, and CHNS analysis techniques, and finally to their Anti-inflammatory profile using cyclooxygenase fluorescence inhibitor screening assay methods along with standard drugs, celecoxib, and diclofenac. The ADMET studies were used to predict which compounds would be suitable for oral administration, as well as absorption sites, bioavailability, TPSA, and drug likeness. According to the results of ADME data, all of the produced chemicals can be absorbed through the GIT and have passed Lipinski’s rule of five. Through molecular docking with PyRx 0.8, these

Poisoning with toxic substances accidently or deliberately can be life threatening and especially in some countries that lack the essential tests and facilities to identify the types and causes of these toxic substances. In Iraq, as many other countries, poisoning is one of the chronic public health problems. However, very little literature about the pattern of poisoning cases, types and age is available in Duhok Governorate. Therefore, this study was conducted to determine the most common patterns of poisoning and the related age and gender in Duhok Governorate from 2016-2018, which would possibly contribute to the early diagnosis and treatment of poisoning. The present study was conducted for three years, started from 1^st of

The coronavirus-pandemic has a major impact on women's-mental and physical-health. Polycystic-ovary-syndrome (PCOS) has a high-predisposition to many cardiometabolic-risk factors that increase susceptibility to severe complications of COVID-19 and also exhibit an increased likelihood of subfertility. The study includes the extent of the effect of COVID-19-virus on renin-levels, glutathione-s-transferase-activity and other biochemical parameters in PCOS-women. The study included 120 samples of ladies that involved: 80 PCOS-patients, and 40 healthy-ladies. Both main groups were divided into subgroups based on COVID-19 infected or not. Blood-samples were collected from PCOS-patients in Kamal-Al-Samara Hospital, at the period between Decembe

يهدف البحث الى:تغطية الافاق الهندسية لمتغيرات الاضاءة في المؤسسات العامة والخاصة والمتمثلة بـ (التباين ونسبة الاضاءة والسطوع ووقت الرؤية ودرجة الانعكاس) وتأثيرها في عملية الادراك البصري المقترن براحة الرؤية للمستخدمين

جهود العلماء في تحديد معنى الإقرار

وحقيقته في الفقه الإسلامي

ملخـــص البحــــث

سورة النحل من سور القرآن الكريم المكية , تحدثت سورة النحل كشأن السور المكية باستفاضة عن مسائل الشريعة وأصولها , التي تنظم الشؤون الداخلية والخارجية للمسلمين , وهي تُعنى بجانب العقيدة والأخلاق والحياة الاجتماعية لتهذيب النفس الانسانية .

تضمنت السورة عدداً من الموضوعات منها العدل والاحسان , والوفاء بالعهد , وابطال الفحشاء والبغي والتوحيد ونقص العهود , وما على ذلك من

معنى وشروط الحركة والاتجاه في تصاميم الاقمشة المطبوعة في العراق

ملخـــص البحــــث

    طبيعة البحث تهدف الى بيان دقة اختيار السياق القرآني لألفاظه فكل لفظة لايمكن ان يسد مسدها لفظ آخر وان كان مرادف له في الدلالة الا ان هناك من الفروق الدلالية الدقيقة بين تلك الألفاظ حتمّت على النص اختيار الفاظ  دون سواها وكيف ان للسياق الدور الاكبر في هذا الاختيار