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The role of TNF-? in the pathogenesis of multiple myeloma “a study in Iraqi patients”
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During recent years, there has been an increasing interest in the investigation of the cytokines roles in pathogenesis of cancer, thus the study aimed at evaluating the level of tumor necrosis factor-alpha(TNF-?) in sera of Iraqi multiple myeloma (MM) patients. Beta 2-microglobulion (?2-m) was assessed to determine if there was any association between this cytokine and the level of ?2- m, as the latter is related to the stage of the disease. In addition, the age and gender were also taken into consideration. Furthermore, we investigated the relationship between IgG and TNF-? in sera of patients. 49 Iraqi patients (27 males and 22 females).The patients were also divided into two groups: the first group included (17) patients who were recently diagnosed and not received any treatment at the time of collecting samples while the second group included (32) patients who received treatment. A further group was also investigated which included (12) apparently healthy individuals (9 males and 3 females), who were regarded as a control group. Serum TNF-? and ?2- m were determined using enzyme-linked immunosorbent assay (ELISA).while the concentration of IgG was measured by radial immune diffusion plates The study reached to the following results: TNF-? levels were not significantly elevated in the patients with MM compared to control group (5.98 ± 8.47 SD vs. 4.85 ± 12.1 SD) and no significant differences (P > 0.05) were observed in the mean (6.02 ±8.1SD vs 5.9 ±9.4SD) concentration of TNF-? in patients with MM who received treatment, when compared with those who did not take the treatment .In addition, there are positive significant correlations between TNF-? and ? 2 Microglobulin (r = 0.316, P = 0 .027), and no relationship between IgG and TNF-? (r = - 0.032, P = 0.829).Furthermore, the study observed that, there was no correlation between TNF-? on the one hand and factors of age and gender on the other hand.

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Publication Date
Mon Feb 04 2019
Journal Name
Iraqi Journal Of Physics
Structural and optical properties of CdO and CdO0.99Cu0.01 thin films prepared by pulsed laser deposition technique
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Structural and optical properties of CdO and CdO0.99Cu0.01 thin
films were prepared in this work. Cadmium Oxide (CdO) and
CdO0.99Cu0.01semiconducting films are deposited on glass substrates
by using pulsed laser deposition method (PLD) using SHG with Qswitched
Nd:YAG pulsed laser operation at 1064nm in 6x10-2 mbar
vacuum condition and frequency 6 Hz. CdO and CdO0.99Cu0.01 thin
films annealed at 550 C̊ for 12 min. The crystalline structure was
studied by X-ray diffraction (XRD) method and atomic force
microscope (AFM). It shows that the films are polycrystalline.
Optical properties of thin films were analyzed. The direct band gap
energy of CdO and CdO0.99Cu0.01 thin films were determined from
(αhυ)1/2 v

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Publication Date
Mon Jan 01 2024
Journal Name
Aip Conference Proceedings
Synthesis and characterization of (Fe2O3)1-x(MgO)x thin film composites for NH3 gas sensors
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This research is presenting a study of optical and structural properties of (Fe2O3)1-x(MgO)x composites synthesized as thin film that can be used as a gas sensor. Pulsed laser deposition technique was used to prepare thin films of (Fe2O3)1-x(MgO)x. The pattern of X-ray diffraction of the composites powder showed the consistency of iron oxide (α-Fe2O3) hematite phase along with the planes (104) and (110) as preferred planes for crystal growth where the intensities of which varied with MgO content. The crystal size of the thin film material was varied in between (26.8-35.1) nm. The diffraction pattern of the pulsed laser deposited thin films was absent from any diffraction peaks. The maximum transparency obtained of hematite

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Publication Date
Wed Feb 29 2012
Journal Name
Al-khwarizmi Engineering Journal
Effect of Fuel Cetane Number on Multi-Cylinders Direct Injection Diesel Engine Performance and Exhaust Emissions
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Due to the energy crisis and the stringent environmental regulations, diesel engines are offering good hope for automotive vehicles. However, a lot of work is needed to reduce the diesel exhaust emissions and give the way for full utilization of the diesel fuel’s excellent characteristics.

A kind of cetane number improver has been proposed and tested to be used with diesel fuel as                 ameans of reducing exhaust emissions. The addition of (2-ethylhexyl nitrate) was designed to raise fuel cetane number to three stages, 50, 52 and 55 compared to the used conventional diesel fuel whose CN was 48.5. The addition of CN improver results in the decre

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Publication Date
Fri Jan 01 2021
Journal Name
Aip Conference Proceedings
Structural, morphology and optical properties of AlxSb1-x thin films prepared by Pulsed laser deposition (PLD)
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AlxSb1-x compounds with different aluminum content(x=0.1, 0.3 , 0.5 , 0.7 and 0.9 ) were prepared by mixing the two elements in the appropriate ratios in quartz ampulla which then sealed and put in an oven at 1273 and left 5 hours. The obtained powder were grinded and then pressed in pellets shape which will be the target to prepare thin films samples. AlxSb1-x thin films were synthesized by PLD with ~ 150nm in thickness .The structures of AlxSb1-x powders and thin films were determined using X–ray diffraction. The data revealed that all the prepare AlxSb1-x bulk and thin films have polycrystalline . The results showed that increasing of Al reduced the crystallinity of the prepared samples at the first but then the opposite take pla

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Publication Date
Wed Jun 26 2019
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Synthesis, Characterization and Acute Anti-inflammatory Evaluation of New Mefenamic Acid Derivatives Having 4-Thiazolidinone Nucleus
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Mefenamic acid (MA) is one of the non-steroidal anti-inflammatory drugs, it is widely used probably due to having both anti-inflammatory and analgesic activity, the main side effects of mefenamic acid include gastrointestinal tract (GIT) disturbance mainly diarrhea, peptic ulceration, and gastric bleeding. The analgesic effects of NSAIDs are probably linked to COX-2 inhibition, while COX-1 inhibition is the major cause of this classic adverse effects. Introduction of thiazolidinone may lead to the increase in the bulkiness leads to the preferential inhibition of COX-2 rather than COX-1 enzyme. The study aimed to synthesize derivatives of mefenamic acid with more potency and to decrease the drug's potential side effects, new series of 4-t

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Publication Date
Sun Dec 25 2022
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Epicatechin product of Camellia sinensis leaves detection by thin layer chromatography and high performance liquid chromatography
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The current study performed in order to detect and quantify epicatechin in two tea samples of Camellia sinensis (black and green tea) by thin layer chromatography (TLC) and high performance liquid chromatography (HPLC). Extraction of epicatechin from black and green tea was done by using two different methods: maceration (cold extraction method) and decoction (hot extraction method). Qualitative and quantitative determinations of epicatechin in two tea samples were investigated. Epicatechin identification was made by utilizing preliminary chemical tests and TLC. This identification was also boosted by HPLC and then quantified epicatechin in all ethyl acetate fractions of two tea samples. This research revealed the existence of epica

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Publication Date
Wed Jun 03 2026
Journal Name
F1000research
Green biosynthesized silver nanoparticles using aqueous extract of Salix alba: antimicrobial and cytogenetic effects on mitosis
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Background Green synthesis of silver nanoparticles (AgNPs) using plant extracts has gained increasing attention as an environmentally friendly alternative to conventional chemical methods. Salix alba L contains bioactive phytochemicals that can act as reducing and stabilizing agents during nanoparticle synthesis. This study aimed to synthesize AgNPs using an aqueous bark extract of S. alba and to evaluate their antimicrobial and cytogenetic effects. Methods Silver nanoparticles were synthesized by mixing S. alba aqueous e

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Publication Date
Thu Feb 01 2024
Journal Name
Doklady Chemistry
Synthesis, Characterization, and Biological Evaluation of New Cyclic Quinazoline Derivatives as Potential Antibacterial and Antifungal Agents
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Heterocyclic compounds are crucial for medicinal chemistry and the development of therapeutic agents like broad-spectrum antibiotics. This study devised a facile procedure to synthesize novel antimicrobial bicyclic heterocycles from 2-mercapto-3-phenylquinazolin-4(3H)-one. Advanced analytical techniques including 1 H and 13C NMR, elemental analysis, and FT-IR spectroscopy characterized the intricate chemical structures of the products. In vitro assays tested the heterocycles against aerobic and anaerobic bacterial strains using fluconazole and ciprofloxacin as antifungal and antibacterial controls. Results demonstrated the formidable broad-spectrum antibacterial and antifungal activities of the synthesized compounds, with growth inhibition

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Publication Date
Wed Jul 01 2026
Journal Name
Journal Of Materials In Civil Engineering
Optimum Proportions and Properties of Foamed Concrete Made with Waste Plastic as Fine and Coarse Aggregate
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This research aimed to explore the use of foamed concrete (FC), a lightweight concrete, by replacing sand with crushed plastic from washing machines to improve environmental and thermal properties. The primary components included traditional materials like cement, water, and a foaming agent, along with the innovative use of waste plastic (WP). Utilizing Minitab software, the study applied the Response Surface Method to optimize mix designs, reducing the experimental mixtures to 31, which were then tested for dry density, porosity, water absorption, shrinkage, compressive strength, splitting tensile strength, and thermal conductivity. Results indicated a significant 24% reduction in dry density when using plastic as fine and coarse aggregate

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Publication Date
Fri Dec 01 2023
Journal Name
Russian Journal Of General Chemistry
Preparation, Characterization, and Biological Activity of Mixed Schiff Base Ligand Complexes with Amino Acid L-Proline
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