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bsj-2398
Preparation and Characterization some New of Naproxen Drug Derivatives
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In this research four steps of the new derivatives of Naproxen drug have been made which are known as a high medicinal effectiveness; the first step involved converting Naproxen into the corresponding ester (A) by reaction Naproxen with methanol absolute in presence H2SO4. While the second step involved treatment methyl Naproxen ester (A) with hydrazine hydrate 80% in presence of ethanol .The third reaction requires synthesis of Schiff bases (C1-C10) by condensation. of Naproxen hydrazide (B) with many substituted aromatic aldehydes . Finally, the fourth step synthesized new tetrazole derivatives ( D1- D10) by the reaction of the prepared Schiff bases (in the third step) with Sodium azide in THF as a solvent .The prepared compounds were characterized by physical properties ,(FT-IR) ,UV, and somewhat of them by 1H-NMR, 13C-NMR spectroscopy.

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Publication Date
Wed Jan 04 2017
Journal Name
Iraqi Journal Of Science
Histological study of the Isotretinoin drug effect on the intrauterine prenatal development in the pregnant mice
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Publication Date
Sun Jul 07 2024
Journal Name
Pakistan Journal Of Life And Social Sciences
Antibacterial Activity of Silver Nanoparticles Prepared from Camellia Sinensis Extracts in Multi-Drug Resistant Pseudomonas aeruginosa
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The purpose of this study to synthesize and characterize silver nanoparticles using phenolic compounds obtained from Camellia sinensis, to test the antibacterial properties of biosynthesized nanoparticles on the formation of biofilms in multidrug-resistant Pseudomonas aeruginosa. Ten isolates of P. aeruginosa were obtained from the Genetic Engineering and Biotechnology Institute laboratories of the University of Baghdad. By using the VITEK-2 system and culturing the isolates on cetrimide agar, the diagnosis was confirmed. Camellia sinensis silver nanoparticles (CAgNPs) were created using an extract of the plant's aqueous and methanolic leaves. Based on the results of the nanoparticle synthesis, spherical nanoparticles that may be single or

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Publication Date
Mon Nov 29 2021
Journal Name
Iraqi Journal Of Science
Histological study of the Isotretinoin drug effect on the intrauterine prenatal development in the pregnant mice
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The isotretinoin drug is 13-cis-retinoic acid, is the treatment of severe acne and some skin cancers and used for dermatological conditions, this study was designed to detect the toxic role of the isotretinoin on the intrauterine development after implantation in albino mice during pregnancy. There are very little studies which indicating the side-effect of this drug on intra-uterine growth, so in the present research we tried to study the toxic effect of isotretinoin on the endometrial changes of uterus during the 2nd. and 3rd. trimester of gestation in pregnant mice after treatment with single chronic dose of the Isotretinoin drug (20 mg/B.wt) from first day of gestation until 21 days the last day of gestation.
The present study exa

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Publication Date
Wed Feb 01 2023
Journal Name
Colloid Journal
Application of Hydrophilic Lipophilic Difference Theory for Fenofibrate Formulation as a Self-Emulsifying Drug Delivery System
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Improved oral bioavailability of lipophilic substances can be achieved using self-emulsifying drug delivery systems. However, because the properties of self-emulsifying are greatly influenced by surfactant amount and type, type of oil used, droplet size, charge, cosolvents, and physiological variables, the synthesis of self-emulsifying is highly complex; consequently, only a small number of excipient self-emulsifying formulations has been developed so far for clinical use. This study reports a highly effective procedure for developing self-emulsifying formulations using a novel approach based on the hydrophilic-lipophilic difference theory. Microemulsion characteristics, such as the constituents and amounts of oil and surfactant electrolyte

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Publication Date
Fri Sep 17 2021
Journal Name
Canadian Journal Of Physics
Synthesis, characterization, photoluminescence, and antibacterial activities of silica-graphene oxide composites
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In this research, a novel thin film Si-GO10 and nanopowders Si-GO30 of silica-graphene oxide (GO) composite were prepared via the sol–gel method and deposited on glass substrates using spray pyrolysis. X-ray diffraction (XRD) results showed a relatively strong peak in the graphite layer that corresponds to the (002) plane. Transmission electron microscope (TEM) images showed that SiO2 nanoparticles were randomly distributed on the surface of GO plates, and the particle size in these nanopowders was below 50 nm. Field emission scanning electron microscopy (FESEM) analysis demonstrated that silica nanoparticles on the surface of GO plates exhibited almost spherical and rod-like nanoparticle shape, which in turn confirmed the formation of Si

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Publication Date
Sat Nov 20 2021
Journal Name
Al-mustansiriyah Journal Of Science
Biosynthesis and Characterization of TiO2 Nanoparticles by Lactococcus lactis ssp. lactis
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Lactococcus lactis ssp. lactis isolated from raw milk was used for titanium dioxide (TiO2) nanoparticles biosynthesis. Biosynthesized TiO2 nanoparticles were characterized using UV-vis spectroscopy, Atomic Force Microscopy (AFM) (1.97 nm), X-ray diffraction (XRD) appa-ratus, Field Emission Scanning Electron Microscopy (FE-SEM), Energy dispersive X-ray anal-ysis (EDX) spectra and Fourier Transform Infrared Spectroscopy (FTIR). Result was 408.21 cm-1 that belong to anatase Titania. L. lactis ssp. Lactis isolates had the ability to synthesize TiO2 nanoparticles, the characterization results presented that the biosynthesized nanoparti-cles were at wavelength (344-347) nm; approving the formation of anatase phase of TiO2 NPs; spherical c

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Publication Date
Fri Jul 29 2022
Journal Name
Research Journal Of Pharmacy And Technology
Characterization and Testing the properties of PEKK- Strontium- hydroxyapatite composite material
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Polymers, being one of the most important materials in dentistry, offer great physical and mechanical qualities, as well as good biocompatibility. Aim of this study was done to evaluate the Polyetherketoneketone and Polyetherketoneketone polymer composite material used as dental implant through tensile strength, Fourier Transform Infrared analysis FTIR, and wettability). Polyetherketoneketone composites (Polyetherketoneketone and Strontium-containing hydroxyapatite) with selected weight percentage ratios of (0, 10%, 20%, 30%), were fabricated using a compression molding technique”, The study involved Samples preparation (sheets) shaped and form into the desired shape according to standard for tests which included tensile strength,

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Publication Date
Wed Apr 19 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Characterization of CdO film AFM and XRD Diffraction Using Rietveld Refinement
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Nano particles of Cadmium Oxide (CdO) thin films were prepared by spray pyrolysis technique. The synthesized film is annealed at (200 , 300, 450) o C for 3 hours .  The XRD and AFM for the analysis of its structural and micro-structural characteristic has been preformed. The average grain size was found to be about 32.50 nm .There is a preferred orientation along (200)   plane  with texture coefficient 1.79, 1.644, 1.763 and 1.792  for deposited and annealed films, corresponding to grain size 57,58 ,51 and 51 nm. The variations of stress with temperature is ranged from 0.157 - 0.376 GPa .
 

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Publication Date
Sat Jun 15 2019
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Isolation and Characterization Salt Tolerant Strains Of Rhizobium leguminosarum bv. Viciae
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Seven strains of Rhizobium leguminosarum bv. vicide were isolated
and purified from the root nodules of faba bean (Viciae faba) plants
collected from different agroclimatic locations in Baghdad and Diyala
provinces of Iraq. Screening of these strains gives four salinity tolernat  strains which tolerate 1-5% sodium chloride supplement mannitol to  salt yeast extract (M Y) medium. Colony forming units for the four tolerant strains under stress conditions were significantly reduced in comparison with those under normal conditions. Different tests were used to study the surface properties of stress tolerant strains under  normal and stress conditions. No differences were found in the production of lipopolysaccharid

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Publication Date
Sun Dec 30 2018
Journal Name
Journal Of Engineering
Synthesis and Characterization of Titanium Dioxide Nanoparticles under Different pH Conditions
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Ethanol as a solvent, a precursor of titanium isopropoxide and a stabilizer of either hydrochloric acid or ammonium hydroxide was used to prepare a titanium dioxide aqueous solution. The aqueous solutions with different values of pH and the morphology of the resultant reaction of the nanoparticles of titanium dioxide were investigated. The X-ray diffraction showed that at low temperatures and with acidic solutions, rutile structures are more favorable to grow on titanium dioxide synthesized, while at low and average temperatures and with base solutions, anatase phase is more pronounced. The crystalline form and the re-confirmation of the crystallite size growth were observed by the scanning electron microscopy. The atomi

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