In this research four steps of the new derivatives of Naproxen drug have been made which are known as a high medicinal effectiveness; the first step involved converting Naproxen into the corresponding ester (A) by reaction Naproxen with methanol absolute in presence H2SO4. While the second step involved treatment methyl Naproxen ester (A) with hydrazine hydrate 80% in presence of ethanol .The third reaction requires synthesis of Schiff bases (C1-C10) by condensation. of Naproxen hydrazide (B) with many substituted aromatic aldehydes . Finally, the fourth step synthesized new tetrazole derivatives ( D1- D10) by the reaction of the prepared Schiff bases (in the third step) with Sodium azide in THF as a solvent .The prepared compounds were characterized by physical properties ,(FT-IR) ,UV, and somewhat of them by 1H-NMR, 13C-NMR spectroscopy.
The research aims to find the impact of a proposed strategy according to the Luria model on realistic thinking among fifth-class scientific students and their achievement in mathematics. To achieve it, the experimental research method and the quasi-experimental design were used for two equal groups, one of them is a control group taught in traditional way and the other is an experimental one taught according to strategy based on Luria model. The research community represents the students of the fifth scientific class from the General Directorate of Education of Karkh First. The research sample (40) students were deliberately chosen and distributed equally between the two groups after making sure that they were equals in their previo
... Show MoreThe first step in this research is to find some of the necessary estimations in approximation by using certain algebraic polynomials, as well as we use certain specific points in approximation. There are many estimations that help to find the best approximation using algebraic polynomials and geometric polynomials. Throughout this research, we deal with some of these estimations to estimate the best approximation error using algebraic polynomials where the basic estimations in approximation are discussed and proven using algebraic polynomials that are discussed and proven using algebraic polynomials that are specified by the following points and if as well as if .
For the second step of the work, the estimatio
... Show MoreIn this work, the annual behavior and cross-correlation between three different solar-ionospheric indices were evaluated: Smoothed Sunspot Number (SSN), Ionospheric T-Index (T-index), and Solar Flux (F10.7 cm) index during solar cycles 23 and 24. The annual behavior for the three tested indices of the maximum and minimum years of the two solar cycles was studied. The correlative conducts between the studied indices were evaluated for the studied periods (1996-2008) and (2008-2019) of the 23rd and 24th solar cycles. The annual correlation between the studied indices was represented by the linear regression equation. The suggested mutual correlation equation gave a good agreement with the observed annual average values of the test
... Show MoreIn this paper, customers’ expectations are continually shifting due to the business environment’s growing competition and substantial changes. As a result, organisations no longer viewed it as a static objective but as an ever-evolving aim. From this vantage point, the research has explored the accounting literature in search of novel approaches to addressing the strategic dimensions of quality, cost and time. Getting them to respond positively to the customer’s requests also requires recognising their needs and controlling their impact on these dimensions. With the removal of operations that do not contribute any value to the product’s value chain and a reduction in manufacturing costs through continuous improvement, the ou
... Show MoreSince its first description as a cytotoxic agent, Olea europaea leaves extract gained significant popularity against human breast cancer, ethyl acetate extract of Olea europaea leaves obtained by acid hydrolysis method was evaluated in vitro as cytotoxic agent against new human breast cancer (AMJ13) cell line, using the MTT assay. One main pentacyclic triterpenoid; oleanolic acid, was isolated from leaves of Olea europaea by well-known two different methods, but not used for this compound before, the acidic hydrolysis method and basic acidic method. The presence of oleanolic acid was proved in both methods with qualitative and quantitative d
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