The aim of the present study is to highlight the role of total cholesterol (TC), triacylglycerol (TG), Glycated hemoglobin A1c and iron in Iraqi women with multiple sclerosis and also to examine the biochemical action of copaxone (which is the most widely used in the 21st century to treat multiple sclerosis) on these biochemical parameters. This is the first study in Iraq which deals copaxone action on TC , TG , HbA1c and iron. Ninety women in their fourth decade suffering from multiple sclerosis were enrolled in this study. They were divided into: the first (group B) composed of (30) women without any treatment related to multiple sclerosis or any treatment linked with chronic or inflammatory diseases. The second (group A1) included (30) women under treatment with copaxone for 1 year, whereas the third group (group A2) involved (30) women under treatment with copaxone for 2 years. Patients groups were compared with a healthy control group (group C) composed of (30) healthy women, TC, TG, HbA1c and iron levels were determined in the sera of patients and control groups. Results of the present study has revealed that TC was high significantly increasing in the sera of group B (250.68±9.76) mg/dl compared with group C (175.36±8.81) mg/dl, while it was high significantly decreasing in the sera of groups A1 (211.88±5.90) mg/dl and A2 (212.12±5.60) mg/dL compared with group B (250.68±9.76) mg/dl. Beside, a non-significant difference was suggested between groups A1 (211.88±5.90) mg/dl and A2 (212.12±5.60) mg/dl. The present study also reported that TG was high significantly increasing in group B (224.84±10.76) mg / dl compared with group C (131.36±7.53) mg/dL whereas a significant decrease was shown in group A1(142.48±4.63) mg/dl and group A2 (195±4.20) mg/dl compared with group B (224.84±10.76) mg / dl. Surprisingly, a highly significant increase was reported in group A2 (195±4.20) mg/dl compared with group A1(142.48±4.63) mg/dl. The present study also suggested that HbA1c level was high significantly increasing in the sera of group B (6.53±0.57) mg/dl compared with group C (4.99±0.07) mg/dl. Oppositely, it was high significantly decreasing in the sera of groups A1 (4.72±0.42) mg/dl and A2 (4.53±0.35) mg/dl compared with group B (6.53±0.57) mg/dl. Futhermore, a non-significant difference was noted between groups A1 (4.72±0.42) mg/dl and A2 (4.53±0.35) mg/dl. This study also reported that iron level was high significantly decreasing in the sera of group B (37.31±4.24) µg / dl compared with group C (98.23±9.21) µg/ dl, whereas it was significantly increasing in the sera of groups A1 (44.05±6.32) µg/dl and A2 (45.31±6.82) µg/dl compared with group B (37.31±4.24) µg/dl . A non significant difference was shown between groups A1 (44.05±6.32) µg / dl and A2 (45.31±6.82) µg / dl.
Laboratory model tests were performed to investigate the behavior of shallow and inclined skirted foundations placed on sandy soil with R.D%=30 and the extent of the impact of the positive and negative eccentric-inclined loading effect on them. To achieve the experimental tests, it was used a box of (600×600) mm cross-sectional and 600mm in height and a square footing of (50*50) mm and 10 mm in thickness attached to the skirt with Ds=0.5B and various an angle of (10°, 20°, 30°). The results showed that using skirts leads to a significant improvement in load-carrying capacity and decreased settlement. In addition, when the skirt angle increased, the ultimate load improved. Load-carrying capacity decreased with increasing eccentri
... Show MoreThis study aims to isolate the pathogenic yeasts from genital tract and investigate their relationship with the age .The results clarified that the most pathogenic yeast isolated from genital tract was Candida albicans , also the results of C.albicanas isolates susceptibility test, to different antifungal revealed that they were sensitive to Miconazole, Ketoconazole and Clotrimazol and were resistant to Nystatin and Grisofulvin. The study of relationship of vaginal infection with the age showed that the incidence of infection with Candida was high among females age group (19-39 years).
Multiple sclerosis (MS) is a chronic, inflammatory demyelinating disease of central nervous system with complex etiopathogenesis that impacts young adults (Lee et al., 2015), and MS impacts younger and middle aged character and leads to a range of disabilities that can alter their daily routines (Yara et al, 2010). Although, the exact cause of MS is still undetermined, the disease is mediated by adaptive immunity through the infiltration of T cells into the central nervous system (Bjelobaba et al, 2017). MS causes the Focal neurological symptomsand biochemical changes in the molecular level and the variation of neural cells such as loss or alteration of sensation, motor function, visible signs such as blurred vision or transient blindness,
... Show MoreThe present study aimed to look for the differences in the oxidative stress status in sera and saliva samples of type 2 diabetic Iraqi patients with and without proliferative diabetic retinopathy. As well as to look for the possibility whether this status can be measured in saliva as an alternative sample to that of serum, hence to achieve that total oxidant status, total antioxidant status and oxidative stress index were measured in both sera and saliva samples of two groups of patients with type 2 diabetes mellitus and the healthy individuals. Upon the comparison between patients without proliferative diabetic retinopathy and the control sample the results showed presence of a significant increase (p < 0.05) of total oxidant st
... Show MoreBackground: Multiple myeloma (MM) is characterized by clonal proliferation of malignant plasma cells within the bone marrow. In most patients, monoclonal immunoglobulin heavy chains or light chains are produced and are associated with organ dysfunction. The growth factor B-cell activating factor (BAFF) plays an important role in the pathogenesis of multiple myeloma due to its ability to promote B-cell survival, expansion, and differentiation. Objective: to measure the circulatory level of B-cell activating factor in multiple myeloma patients in relapsed and remission states and explore its possible correlations with the clinical staging, β2-microglobulin, and interleukin-6. Methods: This cross-sectional study was performed on 60
... Show MoreThe objective of this study is to determine levels of some pro-inflammatory cytokines (IL-12 and SIL-2R) in pregnant women with polycystic ovary syndrome (PCOS) and also to determine incidence of spontaneous abortion during first trimester in pregnant women with PCOS compared with non-PCOS pregnant women. This Study was performed on (93) women, consisted of: 1- (63) pregnant women during the first trimester, which included:A- (33)PCOS pregnant women and subdivided into the following groups: (20) successful pregnant PCOS, (7) blighted Ovum PCOS and (6) missed abortion PCOS. B- (30) non-PCOS pregnant women, which included: (27) successful pregnant control and (3) non-PCOS pregnant women were withdrawn from this study because of their abortion
... Show MoreBackground: Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age with primary manifestations of infertility, menstrual dysfunction and clinical or biochemical hyperandrogenism (hirsutism, acne and elevated androgen). Adiponectin is the most abundant adipokine. It has insulin-sensitizing, anti-atherogenic, and antiinflammatory actions.Objective: Low adiponectin levels in women with PCOS have been largely attributed to obesity which is common among these patients. Therefore, the aim of this study was to measure adiponectin levels in normal weight women with PCOS and its contribution to development of disease.Subjects and Methods: Fifty two (52) women were included in this study with age ra
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