Spectrophotometric Determination of Paracetamol in bulk and Pharmaceutical Preparations

Rafah K. Ahmed; Saud S.  Muhammad; Enaas A. Khodaer

doi:10.21123/bsj.2015.12.2.317-323

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Publication Date

Sun Jun 07 2015

Journal Name

Baghdad Science Journal

Volume

12

Issue Number

2

DOI

10.21123/bsj.2015.12.2.317-323

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Spectrophotometric Determination of Paracetamol in bulk and Pharmaceutical Preparations

Spectrophotometric determination

Paracetamol

Diazotisation.

Rafah K. Ahmed

Saud S. Muhammad

Enaas A. Khodaer

...Show More Authors

A simple, and rapid spectrophotometric method for the estimation of paracetamol has been developed. The methods is based on diazotisation of 2,4-dichloroaniline followed by a coupling reaction with paracetamol in sodium hydroxide medium. All variables affecting the reaction conditions were carefully studied. Beer's law is obeyed in the concentration range of 4-350 ?gml?1 at 490 nm .The method is successfully employed for the determination of paracetamol in pharmaceutical preparations. No interferes observed in the proposed method. Analytical parameters such as accuracy and precision have been established for the method and evaluated statistically to assess the application of the method.

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Publication Date

Tue Jan 08 2019

Journal Name

Iraqi Journal Of Physics

The structure and optical properties of organic semiconductor bulk hetrojunction blend (NiPcTs/Alq3) thin films

Organic semiconductors

bulk heterojunction blend NiPcTS /Alq3 (B.HJ. blend)

optical properties

XRD.

Atyaf H.

...Show More Authors

The effect of heat treatment on the optical properties of the bulk heterojunction blend nickel (II) phthalocyanine tetrasulfonic acid tetrasodium salt and Tris (8-hydroxyquinolinato) Aluminum (NiPcTs/Alq3) thin films which prepared by spin coating was described in this study. The films coated on a glass substrate with speed of 1500 rpm for 1.5 min and treated with different annealing temperature (373, 423 and 473) K. The samples characterized using UV-Vis, X ray diffraction and Fourier transform Infrared (FTIR) spectra, XRD patterns indicated the presence of amorphous and polycrystalline blend (NiPcTs/Alq3). The results of UV visible shows that the band gap increase with increasing the annealing temperature up to 373 K and decreases with

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Publication Date

Fri Dec 31 2021

Journal Name

Iraqi Journal Of Market Research And Consumer Protection

ULATRAVIOLET ABSORBANCE SEPECTRA FOR ANTIBIOTIC DERIVATIVES (AMINO GLYCOSIDES) USED IN MEDICAL AND PHARMACEUTICAL INDUSTRY: ULATRAVIOLET ABSORBANCE SEPECTRA FOR ANTIBIOTIC DERIVATIVES (AMINO GLYCOSIDES) USED IN MEDICAL AND PHARMACEUTICAL INDUSTRY

Key words: Amino glycosides

organic reagents

ultraviolet-visible spectrometer

melting point apparatus.

Anud M. A.

Ziadan J.

...Show More Authors

Ultraviolet spectrophotometric studies for antibiotic (amino glycoside) derivatives including, Neomycin, Streptomycin, Gentamycin and Kanamycin with special reagents, which are benzoyl chloride; benzene sulfonyl chloride, toluenesulfonyl chloride and phthalic anhydride were made. Amino glycosides derivatives were followed through measurements of the ultraviolet absorbance (A) from which the absorptivity (ε) of the complexes was deduced and molar absorbances using Ultraviolet for products and calculate the number of reagents molecule that combine to amino glycosides.

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Publication Date

Sat Jun 01 2019

Journal Name

Acta Chromatographica

A simple stability-indicating HPLC method for simultaneous analysis of paracetamol and caffeine and its application to determinations in fixed-dose combination tablet dosage form

Ahmed Bassam

Siok-Yee

Nasir Hayat

Ahmed Bassam

Muhammad Nura

Seok-Ming

...Show More Authors

A simple, economic, rapid, reliable, and stability-indicating high-performance liquid chromatography (HPLC) method has been developed and validated for the simultaneous determination of paracetamol (PCM) and caffeine (CF) in solid dosage form. The chromatographic separations were achieved with a Waters Symmetry® C18 column (5 μm, 4.6 × 150 mm), using a mixture of methanol and water (40:60, v/v) as a mobile phase, under isocratic elution mode with a flow rate of 0.8 mL/min, and ultraviolet (UV) detection was set at 264 nm. The oven temperature for the column was set and maintained at 35 °C. The method was validated according to International Conference on Harmonization (ICH) guidelines, and it demonstrated excellent linearity, wi

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(25)

Publication Date

Mon Jun 08 2020

Journal Name

Research Journal Of Chemistry And Environment

High Performance Liquid Chromatographic and Areaunder Curve spectrophotometric Methods forEstimation of Cefixime in Pure and MarketedFormulation: A Comparative Study

Cefixime

HPLC

AUC

spectrophotometric

Marketed Formulation

Bahaa

...Show More Authors

Cefixime is an antibiotic useful for treating a variety ofmicroorganism infections. In the present work, tworapid, specific, inexpensive and nontoxic methods wereproposed for cefixime determination. Area under curvespectrophotometric and HPLC methods were depictedfor the micro quantification of Cefixime in highly pureand local market formulation. The area under curve(first technique) used in calculation of the cefiximepeak using a UV-visible spectrophotometer.The HPLC (2nd technique) was depended on thepurification of Cefixime by a C18 separating column250mm (length of column) × 4.6 mm (diameter)andusing methanol 50% (organic modifier) and deionizedwater 50% as a mobile phase. The isocratic flow withrate of 1 mL/min was applied, the temper

Publication Date

Thu Nov 01 2018

Journal Name

Environmental Technology & Innovation

Extraction of glycyrrhizin from licorice (Glycyrrhiza Glabra L.) by bulk liquid membrane

GlycyrrhizinLicoriceKinetic procedureLiquid membraneExtraction

Wasan O.

Basma I.

Maha Hadi

...Show More Authors

In this work, the extraction of glycyrrhizin from Licorice using bulk liquid membrane technique was developed and optimized. The effect of various parameters such as pH of stripping and donor solutions, temperature, stirring speed and kinetic parameters were investigated. Moreover, to study the impact of the polarity of membrane solvent, two types of extraction solvents were used as a membrane solvent: n-Hexane was used as a non-polar solvent and 1-Hexanol was as a polar solvent. The optimum extraction condition was found (95.53%) using 1-Hexanol, rotating speed was 400 rpm, and pH of the acceptor and donor solutions were 8 and 5.5, respectively. The reaction kinetics constants ( and ) for the transport of glycyrrhizin from the donor pha

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(18)

(13)

Publication Date

Tue Jun 30 2020

Journal Name

Iraqi Journal Of Chemical And Petroleum Engineering

Process Optimization Study of Pb(II) Removal by Bulk Liquid Membrane (BLM)

Lead ions

Xylene oil

Response Surface Methodology

Analysis of Variance.

Nashwan

Hussain

...Show More Authors

Box-Wilson experimental design method was employed to optimized lead ions removal efficiency by bulk liquid membrane (BLM) method. The optimization procedure was primarily based on four impartial relevant parameters: pH of feed phase (4-6), pH of stripping phase (9-11), carrier concentration TBP (5-10) %, and initial metal concentration (60-120 ppm). maximum recovery efficiency of lead ions is 83.852% was virtually done following thirty one-of-a-kind experimental runs, as exact through 2⁴-Central Composite Design (CCD). The best values for the aforementioned four parameters, corresponding to the most restoration efficiency were: 5, 10, 7.5% (v/v), and 90 mg/l, respectively. The obtained experimental data had been

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(3)

Publication Date

Tue Jun 30 2020

Journal Name

Iraqi Journal Of Chemical And Petroleum Engineering

Process Optimization Study of Pb(II) Removal by Bulk Liquid Membrane (BLM)

Nashwan

Hussain M.

...Show More Authors

Box-Wilson experimental design method was employed to optimized lead ions removal efficiency by bulk liquid membrane (BLM) method. The optimization procedure was primarily based on four impartial relevant parameters: pH of feed phase (4-6), pH of stripping phase (9-11), carrier concentration TBP (5-10) %, and initial metal concentration (60-120 ppm). maximum recovery efficiency of lead ions is 83.852% was virtually done following thirty one-of-a-kind experimental runs, as exact through 24-Central Composite Design (CCD). The best values for the aforementioned four parameters, corresponding to the most restoration efficiency were: 5, 10, 7.5% (v/v), and 90 mg/l, respectively. The obtained experimental data had been utilized to st

(3)

Publication Date

Mon Dec 30 2002

Journal Name

Iraqi Journal Of Chemical And Petroleum Engineering

Aerobic Filter Treatment of Pharmaceutical Waste

Nahidh W

Hammodi A

Kassim H

Abbas H

...Show More Authors

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Publication Date

Mon Feb 14 2022

Journal Name

Proceedings Of The National Academy Of Sciences

Pharmaceutical pollution of the world’s rivers

John L.

Alistair B.A.

Dana W.

Kenneth M. Y.

Racliffe W. S.

Cristóbal

Aiko D.

Julie

Marc

Robert A.

Alejandra

Aida

Anja

Pedro

Macarena

Chris

Magdalena

Monique

Thais

Vahagn

Yekaterina

Clare S.

Christopher J.

Thilo

Tapos

Volga

Jessica

Jean L.

Francisco

Maria T. P.

Victorien

Gildas

Oumar

Jules M.

Linda E.

Michelle

Donald

Romaric

Jaime

Guang-Guo

Chang-Er

Martha

Jina

Jean-Paul

John

Suspense A.

Penelope

Silvia

Nikolina

Milena

Despo

Lida

Vladimíra

Jan

María

Bayable A.

Jeanne

Arnaud

Peter

Ilia

Sven

Gerasimos

Halldór P.

Molly

Thatikonda

Manisha

Anindrya

Adee

Nima

Ali

Omar

Salem S.

Francesco

Benny

Tom

Koffi Marcellin

Bakhyt

Raikhan

Lydia

Jemimah K.

Peter

Victor

Nathaniel T.

Sheck

Ahmad Zaharin

Ley Juen

Mahamoudane

Seydou T.

Rik

Olatayo

Muhammad

Ziad

Aaron

Jorge Manuel

María

Heidi

Ian

Fabio

Alhaji Brima

Bashiru M.

Vesna

Mitja

Melusi

Kyungho

Habyeong

John L. Celestino

Andreu

Priyanie

Anna

Gisela

Armin K.

Alex C.

Jheng-Jie

Rebecca

Madaka

Ulas

Turgut T.

Julius B.

Yuliya

Yuriy

Horacio

Andrés

Douglas B.

Maritza

David

Charles

...Show More Authors

Environmental exposure to active pharmaceutical ingredients (APIs) can have negative effects on the health of ecosystems and humans. While numerous studies have monitored APIs in rivers, these employ different analytical methods, measure different APIs, and have ignored many of the countries of the world. This makes it difficult to quantify the scale of the problem from a global perspective. Furthermore, comparison of the existing data, generated for different studies/regions/continents, is challenging due to the vast differences between the analytical methodologies employed. Here, we present a global-scale study of API pollution in 258 of the world’s rivers, representing the environmental influence of 471.4 million people across

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(1362)

(1328)

Publication Date

Tue Sep 01 2020

Journal Name

Al-nahrain Journal Of Science

Spectrophotometric Determination of Co(II) in Vitamin B12 Using2-(biphenyl-4-yl)-3-((2-(2,4-dinitrophenyl) hydrazono)methyl) imidazo [1,2-a]pyridine as Ligand by Flow Injection–Merging Zone Analysis

Suhair

Bushra

Naeemah

...Show More Authors

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