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Heat Shock Protein70 as Biomarker in Bladder Cancer

The present study aimed to shed light on the urine HSP70 concentration of patients with urinary bladder carcinoma UBC and control subjects as new urinary biomarker. The second aim was to associate this protein concentration with UBC stage and grade in patients with UBC. A direct ELISA was used to quantify urine HSP concentrations in 58 patients with urinary bladder carcinoma UBC with different grades (G) and stages (T) all malignant of them was transitional cell carcinoma (TCC) type , 15 from patients with urinary Bladder disorders other than cancer UBD and 15 healthy subjects(control) . Urine concentrations of HSP70 were elevated in patients with UBC compared to those without UBC (healthy and UBD, P< 0.5). There was a high significant between mean level of HSP70 in patients with T2 tumor stage as compared with patients with stage T3 . Also, there was a high significant increased mean level of HSP70 in patients with G3 as compared with patients with grad1 G1.

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Publication Date
Thu Jun 30 2011
Journal Name
Al-kindy College Medical Journal
The Expression of Epstein-Barr virus in Breast cancer in relation to age

Background: Breast cancer is the most common
malignancy affecting females worldwide. The association
of Epstein-Barr virus (EBV) with this cancer is a longstanding
interest to this field.
Aim: to investigate the presence of EBV in breast tumor
tissue in relation to age.
Patients and Methods: Paraffin-embedded tissue blocks
from 45 female patients with breast tumors (ranged in age
from 28 to 85 years) were retrieved. The cases were
grouped into two categories: group (A): included 30 cases
with breast carcinoma and group (B): included 15 cases
with benign breast diseases as a control group .The
expression of EBV protein was examined
immunohistochemically.
Results: Twelve (40%) of the 30 breast canc

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Publication Date
Sun Jan 03 2016
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Assessment of sociodemographic characteristics in a sample of breast cancer patients in Baghdad.

Background: In Iraq, breast cancer is the most common type of malignancy among the Iraqi population in general. It accounts for approximately one third of the registered female cancers according to the latest Iraqi Cancer Registry.
Objectives: This study was conducted to assess the sociodemographic characteristics of patients with breast cancer in Baghdad.
Methodology: This cross sectional study that was conducted in Baghdad City during a three months period from January to March 2016. It was conducted at Al-Amal National Hospital for Cancer Management. The questionnaire form gathered info about sociodemographic characteristics including: age, gender, educational attainment, marital status, living arrangement, finical status, and d

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Publication Date
Tue Jun 30 2015
Journal Name
Al-kindy College Medical Journal
Surgical –Audit on breast cancer risk factors in AL-Russafa district in Baghdad

Background: Breast cancer remains a substantial cause of morbidity and mortality, there is a need for continued efforts to understand the etiology of the disease, maintain screening effort, implement prevention strategies, and develop better treatments.Objective: To analyze the risk factors, improve early detection and prevention of breast cancer in Al-Russafa district- Baghdad, aiming to increase survival rate and improve the quality of life.Methods: A cross sectional audit of 258 breast cancer cases seen at Al-Elwiya maternity teaching hospital from January2009 to December 2011,data collected from patients files were: age, gender , residency, marital status, parity, age at menarche and menopause age at first live birth, hormonal therap

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Publication Date
Fri Apr 30 2021
Journal Name
Al-kindy College Medical Journal
The Expression of Epstein-Barr virus in Breast cancer in relation to age

Background: Breast cancer is the most common
malignancy affecting females worldwide. The association
of Epstein-Barr virus (EBV) with this cancer is a longstanding
interest to this field.
Aim: to investigate the presence of EBV in breast tumor
tissue in relation to age.
Patients and Methods: Paraffin-embedded tissue blocks
from 45 female patients with breast tumors (ranged in age
from 28 to 85 years) were retrieved. The cases were
grouped into two categories: group (A): included 30 cases
with breast carcinoma and group (B): included 15 cases
with benign breast diseases as a control group .The
expression of EBV protein was examined
immunohistochemically.
Results: Twelve (40%) of the 30 breast canc

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Publication Date
Wed Oct 07 2020
Journal Name
Indian Journal Of Forensic Medicine & Toxicology
Correlation of Toxoplasmosis Seroprevalence and Serum Level of Interleukin-10 in Iraqi Breast Cancer Women

Toxoplasmosis is regarded as one of the most important global life-threatening diseases in immune-compromised people. The intracellular protozoon Toxoplasma gondii is the causative pathogen of toxoplasmosis. Aim of this study is to investigate the possible association between T. gondii infection and breast cancer (BC) in Iraqi women, also to assess the effect of T. gondiion interleukin 10 (IL-10) of the immune response. By ELISA method, blood samples from 81 women with breast cancer and 60 apparently healthy women have been examined for presence of anti-toxoplasmaantibodies, also the levels of serum IL-10 were estimated in these subjects. Results showed that women with BC had the highest prevalence rate of toxoplasmosis. The anti- T.gondii

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Publication Date
Sun Oct 02 2011
Journal Name
Journal Of The Faculty Of Medicine Baghdad
In Vitro Study of Mutagenicity and Genotoxicity of Some Bacterial Secretions associated with Bladder Tumors Tissues on Human Lymphocytes by Using Blood Tissue Culture Techniques

Background: Cytogenetic studies have been used to assess carcinogenic or mutagenic exposures and effects early in occupational, biological and environmental settings. Bacterial infection has not traditionally been considered asa major causes of cancer. Bacteria have been linked to cancer by two mechanisms: induction of chronic inflammation and production of carcinogenic bacterial metabolites.
Objective: Because of new concepts in relating infection with certain malignancies the present study is performed. Therefore this study was conducted to determine the effects of bacterial products associated with biopsies of bladder tumor on human lymphocytes tissue cultures in vitro. Moreover, if there is any relation between these products for

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Publication Date
Sun Oct 18 2020
Journal Name
Diagnostics
Diagnostic Accuracy of Oral Fluids Biomarker Profile to Determine the Current and Future Status of Periodontal and Peri-Implant Diseases

Severe periodontitis is ranked as the sixth most prevalent disease affecting humankind, with an estimated 740 million people affected worldwide. The diagnosis of periodontal diseases mainly relies upon assessment of conventional clinical parameters. However, these parameters reflect past, rather than current, clinical status or future disease progression and, likely, outcome of periodontal treatment. Specific and sensitive biomarkers for periodontal diseases have been examined widely to address these issues and some biomarkers have been translated as point-of-care (PoC) tests. The aim of this review was to provide an update on PoC tests for use in the diagnosis and management of periodontal diseases. Among the PoC tests developed so

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Publication Date
Mon Jan 01 2024
Journal Name
2nd International Conference For Engineering Sciences And Information Technology (esit 2022): Esit2022 Conference Proceedings
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Publication Date
Thu Nov 30 2023
Journal Name
Iraqi Journal Of Science
Determination of Spacewise− Dependent Heat Source Term in Pseudoparabolic Equation from Overdetermination Conditions

      This paper examines the finding of spacewise dependent heat source function in pseudoparabolic equation with initial and homogeneous Dirichlet boundary conditions, as well as the final time value / integral specification as additional conditions that ensure the uniqueness solvability of the inverse problem. However, the problem remains ill-posed because tiny perturbations in input data cause huge errors in outputs. Thus, we employ Tikhonov’s regularization method to restore this instability. In order to choose the best regularization parameter, we employ L-curve method. On the other hand, the direct (forward) problem is solved by a finite difference scheme while the inverse one is reformulated as an optimization problem. The

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Publication Date
Thu Nov 30 2023
Journal Name
Iraqi Journal Of Science
Influence of Heat Transform and Rotation of Sutterby Fluid in an Asymmetric Channel

     In this research, the effect of the rotation variable on the peristaltic flow of Sutterby fluid in an asymmetric channel with heat transfer is investigated. The modeling of mathematics is created in the presence of the effect of rotation, using constitutive equations following the Sutterby fluid model. In flow analysis, assumptions such as long wave length approximation and low Reynolds number are utilized. The resulting nonlinear equation is numerically solved using the perturbation method. The effects of the Grashof number, the Hartmann number, the Hall parameter, the magnetic field, the Sutterby fluid parameter, and heat transfer analysis on the velocity and the pressure gradient are analyzed graphically. Utilizing MATHEMATIC

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