Preferred Language
Articles
/
bsj-1440
Lipid Profile Changes in Toxoplasmosis Aborted Women

Blood lipids are important mediators of host defense during the acute phase of innate immunity. Parasites may induce significant changes in lipid parameters, as has been shown in vitro study where substitution of serum by lipid/cholesterol in medium and in experimental models (in vivo). Thus changes in lipid profile occur in patients that having active infections with most of the parasites. Toxoplasma cannot synthesize cholesterol and depends upon acquisition of low density lipoprotein (LDL)-derived from the host cell, via endocytosis mediated by the LDL receptor or the LDL receptor-related protein.The present study is conducted to evaluate the changes in lipid profile in T. gondii infected women.A total of patients included 87 aborted women who had positive test for toxoplasmosis and a two control groups (115 non toxoplasmosis women): The first control group (negative control) contains 88 apparently healthy women and the second control group (positive control) contains 87 aborted women, were registered from Al-Yarmouk Teaching Hospital in Baghdad. Both control groups had negative test for toxoplasmosis. These samples were collected between the period January 2009 and May 2010. Patients and controls women's had comparable age that ranged between 15-45 years old. Serum samples were collected from each woman in the three groups and then the Enzyme Linked Immunosorbant Assay (ELISA) and Lipid profile assays were performed by using two commercial kits. In the basis of ELISA test anti-T. gondii antibodies (IgG and IgM), detected in the patients sera, three types of toxoplasmosis were identified. These were; acute type, sub-acute type and chronic type. Most of patients had chronic type 75 (86.2%). There were significant decreased in the total cholesterol are 165.05 (control groups 212.44, 213.33 respectively), triglycerides 134.98 (control groups 173.81, 174.40 respectively), LDL 87.78 (control groups 137.32, 135.87 respectively) and vLDL values 26.99 (control groups 34.70, 34.60 respectively). In contrast, there was significant increased in HDL value (49.0) as compared with control groups (40.42, 38.78 respectively). Also the result indicated that there were no significant differences in lipid profile values between the three types of disease. Toxoplasma gondii had a role in changes lipid profile values in infected women which characterized by decrease in cholesterol and triglyceride and LDL with a significant increases in HDL level. Further studies needed to maintain the effect of duration of the toxoplasmosis (acute or chronic) on the changes in lipid profile.

Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Tue Nov 01 2016
Journal Name
Journal Of The College Of Basic Education
Publication Date
Fri Mar 15 2019
Journal Name
Journal Of The College Of Education For Women
Geographical Changes in the Marshes of Iraq

Iraq has a range of small and large marshes, which can be divided into two groups, a group of marshes feeding water from the Tigris and Euphrates rivers, and a group of marshes fed by the seasonal valleys coming from the desert plateau and the aljazera plateau.

The marshes have go through major changes, some of them turning into industrial lakes to store the flood waters of the Tigris and Euphrates rivers. Others have been dried up and turned into agricultural land. Others have dried up and the water has been returned to them in less quantities than before.

The purpose of this research is to but light on the changes that have occurred in these marshes, with the mention of marshes turned into industrial lakes or agricultur

... Show More
View Publication Preview PDF
Publication Date
Sat Dec 11 2021
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Anastrozole Loaded Nanostructured Lipid Carriers : Preparation and Evaluation

Anastrozole (ANZ) is considered constitute of the fourth –generation of Non–steroidal aromatase blockage, ANZ has use for hormone receptor positive breast cancer in postmenopausal women. The serious side effects of ANZ including, vaginal dryness, hot flashes, irritability, breast tenderness and un–stability in circulation.

Nanostructured lipid carriers (NLCs) have recently emerged as a multifunctional platform for drug delivery in cancer therapy.

Five formula were composed of (200 mg of glyceryl monostearate, 40 mg of oleic acid , 1% (w/w) Tween 80, 1% (w/w) Poloxamer 407, 1% (w/w) soy lecithin and Vitamin E Polyethylene Glycol Succinate.

The mean particle size, polydispersity index, zeta potential, entrapme

... Show More
Scopus (10)
Crossref (6)
Scopus Crossref
View Publication Preview PDF
Publication Date
Thu May 31 2018
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Seroprevalence of Toxoplasmosis Antibodies among Diabetes Mellitus Patients and Assessment some Biochemical Markers

         Toxoplasma gondii is an protozoan intracellular coccidian protozoan parasite. Latent toxoplasmosis threat to immunocompetent individuals. Diabetic patients are more susceptible to infect with toxoplasmosis due to their low level of immunity response. The purpose of this research is to define the association between toxoplasmosis and diabetes mellitus and detection serum levels of chemokines (monocyte chemoattractant protien-1 and transforming growth factor-β) in diabetic patients infected with toxoplasmosis. Serum samples were collected from 120 diabetic patients and 50 healthy individuals as a control group  from the Imamein Kadhimein Medical City in Baghdad. In order&nbs

... Show More
Crossref (1)
Crossref
View Publication Preview PDF
Publication Date
Sun May 12 2019
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Prevalence of Fibromyalgia in Infertile Women

Background: Fibromyalgia is a functional disorder of growing importance characterized by chronic widespread musculoskeletal pain. It frequently affects women of child bearing age. Infertility is failure to achieve pregnancy within a 12 month period for sexually active individuals under 35 years of age and failure to conceive within a 6 months period for those over 35 years, which can have a major psychosocial impact on the affected person’s life.

Objectives: To estimate the prevalence of fibromyalgia among a sample of infertile women; and to study its relationship with age, length of marriage, duration and type of infertility.

Patients and Methods: A cross-sectional stu

... Show More
Crossref
View Publication Preview PDF
Publication Date
Sun Aug 06 2017
Journal Name
International Journal Of Science And Research
Prevalence Rate of Toxoplasmosis and its Effects on Some Liver Functions in Blood Samples of Volunteers' Students

Recently, young people have shown a desire to keep cats as pets, despite being threatened with health problems including toxoplasmosis. Therefore, the current study was aimed to detect toxoplasmosis infections among of volunteers students as well as spreading health awareness among students and knowledge about the importance of this disease. Prevalence rate and effects of liver functions were tested by measured levels of Aspartate aminotransferase (AST) and Alanine aminotransferase (ALT) enzymes while the OnSiteToxo IgG/IgM combo rapid test was used in the diagnosis of the disease. The blood samples were collected from 76 volunteers (35 male and 41 female). The results showed that, the total percentage of infections was 27.6% and all infect

... Show More
Publication Date
Wed Aug 30 2023
Journal Name
Iraqi Journal Of Science
Periodontal Disease: A Predictive Profile

    Periodontal diseases such as gingivitis and periodontitis are considered common diseases. This study is aimed to predicate these diseases using non-harmful specimens such as saliva throughout the detection of some parameters. In the beginning, a random 51 patients' saliva was collected from outpatients who suffered from different degrees of periodontal diseases. Concurrently, another 40 people who appeared to be healthy were collected, and both patients and healthy people were subjected to a questionnaire form and diagnosed by a specialist dentist. The results of this study revealed that there is no significant difference between males and females in infection with periodontal diseases. As well, smoking is not acting as the main f

... Show More
Scopus Crossref
View Publication Preview PDF
Publication Date
Mon Jan 01 2018
Journal Name
Journal Of Global Pharma Technology
Auto-antibodies Profile in Children Infected with Visceral Leishmaniasis

Visceral leishmaniasis (VL) is a parasitic infection caused by an intracellular growth of Leishmania spp. in macrophage cells. The autoimmune disorder is a condition takes place when the immune system produces antibodies which incorrectly attacked its own body tissues. VL has been involved as an effect or on the autoimmune aspect. This study was conducted to identify the auto antibodies profile in patients infected with VL. The presences of auto antibodies in 21 Iraqi children infected with VL were tested for laboratory autoimmune aspect. The highest percentage of seropositive in Leishmania patients was observed for anti-ds DNA, anti-Mi-2, anti-Ku and anti-PCNA antibodies (90.5%, 90.5%, 90.5% and 61.9%) respectively, while the lowest percen

... Show More
Scopus
Publication Date
Sat Jan 01 2022
Journal Name
Indian Journal Of Tuberculosis
Scopus (8)
Crossref (6)
Scopus Crossref
View Publication
Publication Date
Tue Jun 30 2015
Journal Name
Al-kindy College Medical Journal
Symptoms profile of patients with major depression in Baghdad

:Background: Many studies had stated that there are marked variations in the clinical presentation of depressive states between different cultures.Objectives: The main aim of the study is to identify the symptoms profile of patients with major depressive disorder living in Baghdad.Method: Ninety two patients with major depressive disorder consulting Ibn-Rushd psychiatric teaching hospital were studied thoroughly to identify the frequency of symptoms among them. The fifth edition of the Arabic version of the Mini-International Neuropsychiatric Interview (M.I.N.I) was used to identify the Diagnostic and Statistical Manual – fourth edition (DSM-IV) symptoms. A list of other symptoms, which were found to present variably in depression acco

... Show More
View Publication Preview PDF