Preferred Language
Articles
/
bijps-672
The Impacts of Graded Doses of Pyridoxine on the Biomarkers, Aspartate Aminotransferase, lactate Dehydrogenase and Total Antioxidant Capacity in Doxorubicin-Induced Cardiotoxicity in Female Rats
...Show More Authors

Abstract:

       The aim of the current study was to investigate the possible protective effect of graded doses (5, 10, and 15mg/kg) of pyridoxine hydrochloride intraperitoneally injected against (15mg/kg) doxorubicin-induced cardiotoxicity in female rats. Fifty-six (56) Wistar albino female rats were utilized weighing 180-200 gm allocated into eight groups, seven rats each; Group I: negative control distilled water; Group II: Pyridoxine (5mg/kg); Group III: Pyridoxine (10mg/kg); Group IV: Pyridoxine (15mg/kg); Group V: doxorubicin (15 mg/kg); Group VI: Pyridoxine (5 mg/kg) prior to doxorubicin (15 mg/kg); Group VII: Pyridoxine (10 mg/kg) prior to doxorubicin (15 mg/kg); Group VIII: Pyridoxine (15 mg/kg) prior to doxorubicin (15 mg/kg). DOX caused significant elevations in serum biomarker enzymes of aspartate aminotransferase (AST), lactate dehydrogenase (LDH) and significant reduction in heart tissue homogenate content of total antioxidants capacity (TAOC). Treatment with 15mg/kg pyridoxine for four consecutive days prior to a single dose 15mg/kg doxorubicin resulted in significant reduction in serum enzymes level of AST and LDH. Treatment with 10 or 15mg/kg pyridoxine for four consecutive days prior to a single dose of doxorubicin produced significant increments in TAOC heart tissue homogenate level compared to positive control. In conclusion, pyridoxine supplementation might be a promising adjunctive agent for improving oxidative stress and biological markers for preventing DOX-induced cardiac complications.

Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Tue Sep 05 2023
Journal Name
Migration Letters
The Impact of Climate Change on the Increase in the Frequency of Drought in the Eastern Region of Iraq
...Show More Authors

Aim: This abstract aims to highlight the critical nature of climate change as a pressing challenge facing humanity in the 21st century. It underscores the severe consequences it poses to essential facets of human existence, including water and energy resources, agricultural production, and the broader environmental systems. Method: The abstract primarily utilizes a descriptive approach to emphasize the impact of climate change on the Middle East, particularly the Arab region. It relies on a review of existing knowledge and data related to climate change and its effects on ecosystems and drought patterns. Results: The abstract outlines the direct and indirect repercussions of climate change on human life and the environment. It draws atten

... Show More
View Publication Preview PDF
Publication Date
Sun Jul 01 2018
Journal Name
International Journal Of Geotechnical Earthquake Engineering
Impact Induced Responses of Saturated and Dry Dense Sand
...Show More Authors

The present article includes an experimental study of the behavior of dry and saturated dense sandy soil under the action of a single impulsive load. Dry and saturated dense sand models were tested under impact loads. Different falling masses from different heights were conducted using the falling weight deflectometer (FWD) to provide the single pulse energy. The responses of dense soils were evaluated at surface of soil under impact load. These responses include; displacements, velocities, and accelerations that are developed due to the impact acting at top and the displacement at different depths within the soil using the falling weight deflectometer (FWD) and accelerometers (ARH-500A waterproof, and low capacity acceleration tran

... Show More
Scopus (7)
Crossref (4)
Scopus Clarivate Crossref
Publication Date
Wed Feb 01 2023
Journal Name
Baghdad Science Journal
Phytochemical profile, Antioxidant, Enzyme inhibitory and acute toxicity activity of Astragalus bruguieri
...Show More Authors

The medicinal plants (Astragalus species) have been used traditionally as anti-inflammatory, antioxidant, and Anti-diabetics. The current research investigates the phytochemistry and some biological activity of methanol extract of different parts of Astragalus bruguieri Bioss., a wild medicinal plant grows on Safeen mountain, Erbil, Iraq. The methanol extracts of A. bruguieri were analyzed for total phenolic, flavonoid, and saponin contents. In-vitro antioxidant activity was analyzed by 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays. Furthermore, the plant extracts were examined for in-vitro enzyme inhibitory activity and in-v

... Show More
View Publication Preview PDF
Scopus (10)
Crossref (9)
Scopus Clarivate Crossref
Publication Date
Sun Sep 01 2013
Journal Name
Baghdad Science Journal
Antioxidant and free radical scavenging effects of Iraqi sumac ( Rhus coriaria L)
...Show More Authors

This study was carried out to evaluate the antioxidant activity of Iraqi sumac seeds (Rhus coriaria. L) (Anacardiaceae). Total phenolic compounds and flavoniods were determined in three different sumac seed extracts (SSE) (aqueous,ethanolic and methanolic extract). For extraction Antioxidant activity of SSE were evaluated by various antioxidant assays, including total antioxidant capacity, reducing power,by using 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical scavenging, nitric oxide scavenging, Hydroxyl radical scavenging, and metal ion chelating activities. These various antioxidant activities were compared with ascorbic acid as a standard antioxidant.The results showed that the three(SSE), contained large amounts of phenolic and flavonio

... Show More
View Publication Preview PDF
Crossref (5)
Crossref
Publication Date
Thu Mar 30 2023
Journal Name
Iraqi Journal Of Science
Effect of Total, Northern and Southern Hemisphere Sunspot Number (Ri, Rn and Rs) on F2- Layer Critical Frequencies at Mid- Latitude Rome Station During the Descending Phase of Solar Cycle 23
...Show More Authors

The relationship between F2- layer critical frequencies (foF2), total sunspot number (Ri), northern hemisphere sunspot number (Rn) and southern hemisphere sunspot number (Rs) at station located in mid- latitudes on latitude near to latitude of Iraq (Rome station, lat.: 42o N and lon.: 13o E) and for 2003(the descending phase of solar cycle 23) were studied.
This research work aims to know the correlation range between them, through correlation coefficients which correlate between them, and hence, the dependence on that index for predicting F2- layer critical frequencies. When the correlation coefficients between foF2, Ri, Rn and Rs were compared for different seasons of 2003, It is found that, correlation coefficient between foF2 and

... Show More
View Publication Preview PDF
Publication Date
Tue Jun 20 2023
Journal Name
Baghdad Science Journal
Preparation, characterization, antioxidant activity of 1-(2-furoyl) thiourea derivatives and study the molecular docking of them as potent inhibitors of Urease enzyme
...Show More Authors

In this work, we synthesized thirteen compounds of 1-(2-furoyl)thiourea derivatives 1-13 by conversion of 2-furoyl chloride to 2-furoyl isothiocyanate by reacting it with potassium thiocyanate in dry acetone in a quite short reflux time then, in the same pot, different of (primary and secondary amines) were added individually to achieve thiourea derivatives. The products were characterized spectroscopically using (FT-IR, 1H NMR and 13C NMR) techniques. Some of them were evaluated as antioxidant agents using DPPH radical scavenging method, and all were examined theoretically as enzyme inhibitors against Bacillus pasteurii urease (pdb id: 4ubp) and  by studying  molecular docking using Autodock (4.2.6) software.

View Publication Preview PDF
Scopus (4)
Crossref (3)
Scopus Crossref
Publication Date
Wed Jul 22 2015
Journal Name
Plant Growth Regulation
Effect of photosynthetic photon flux density on growth, photosynthetic competence and antioxidant enzymes activity during ex vitro acclimatization of Dieffenbachia cultivars
...Show More Authors

View Publication
Scopus (10)
Crossref (11)
Scopus Clarivate Crossref
Publication Date
Fri Mar 01 2013
Journal Name
Journal Of Economics And Administrative Sciences
Role of Total Quality tools to reduce costs and improve quality
...Show More Authors

Abstract

The research aims to study the problem of high production costs and low quality and the use of total quality management tools to detect problems of the high cost of failure and low quality products, diagnosis, and developing appropriate solutions.

To achieve the goal, we studied the overall quality tools and its relationship with the costs and the possibility of improving quality through the use of these tools.

Was limited to these tools and study the relation to the reduction of costs and improving quality have been studied serially by the possibility of the reduction.
To achieve the goal, the study of the concept of total quality management

... Show More
View Publication Preview PDF
Crossref (1)
Crossref
Publication Date
Wed Jul 29 2020
Journal Name
Iraqi Journal Of Science
Biological Activities of Iraqi Fig (Ficuscarica) CrudeEthanolic and Total Flavonoids Extracts
...Show More Authors

The present study focuses on the biological strategy for treating cancer and parasitic infections, such as leishmaniasis antiparasitic activity, forthe crude alcoholic extract ofFicus leaves and their extracted total flavonoids with a comparison between their effects.The flavonoids were extracted from the leaves of the mature Ficuscaricausing the reflux extraction method. Total flavonoids were detected qualitatively by TLC techniquewhich demonstratedthat the plant was rich indifferent flavonoids, especially Rutin, Quercetin, Kaempferol, luteolin and others. Quantitatively, the plant total flavonoids content was 337.3 mg / 100 g fig leaves calculated as rutin.The biologicaleffects of the crude and purified total flavonoi

... Show More
View Publication Preview PDF
Scopus (5)
Crossref (2)
Scopus Crossref
Publication Date
Mon Mar 08 2021
Journal Name
Baghdad Science Journal
The effect of unsecured use of chemical pesticides on the environment and health in Iraq
...Show More Authors

The wide use of pesticides in recent years leads to rapid distribution of these pollutants in the environment (air, water and soil).They were transported by means of air or water to biological ecosystems. They become more toxic through the processes of biological magnification while some of them persist for along period.The aim of this work is to show the negative effect that chemical pesticides causes, and in the same to show their side effect on the environment and health in Iraq. We could conclude that the bad use of these chemicals could cause an urgent impact now or in the future. Governmental offices dealing with these materials should take the right measures to minimize the danger and the misuse of these chemicals by seeking alternat

... Show More
View Publication Preview PDF