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Antiplatelts Activity of Vitamin E in Relation to Dose and Duration of Therapy
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           Vitamin E, having the well known antioxidant activity  through scavenging free radicals Ùˆ it occurs in several  isomeric forms , these isomers have relatively different functions . One of these actions is related to its ability to inhibit platelets aggregation and hence thrombosis. The present study included a total number of apparently healthy  62 males . 11of them served as standard group , treated  with 100 mg aspirin /day for more than one month . Another 31 subjects were randomly grouped into 5 groups that received different daily doses of α – tocopherol : 400 IU , 800 IU and 1200 IU for  2-6 months.The remainder ( 20 ) subjects served as  a control  group ( received no therapy ) . Platelets function was assessed based on measuring bleeding time and  Slide Platelets  Aggregation Time ( SPAT ) Meanwhile , thiobarbituric acid reactive substances  (TBARS) were measured as a marker for oxidative stress. The results showed that the commercially available vitamin E preparations  (α- tocopherol ) could exert anti-coagulant effect ,such effect is more dependant on duration of therapy , rather than dose related action .In addition to it’s antioxidant effect, which seems to be significantly correlated to it’s antiplatelets effect  ( r=0.994 ,p<0.05).Hence , long  term administration   of high doses of vitamin E  could be effective in decreasing the incidence of thrombosis ,which in turn depends on platelets function. Such effect might not affect bleeding time obviously , but it could reduce chances for platelets recruitment , which might represent an additional advantageous action for vitamin E  over other antioxidants.

Key Words :  Vitamin E  , α -  Tocopherol ,   Antiplatelets

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Publication Date
Wed Oct 11 2023
Journal Name
Journal Of Educational And Psychological Researches
Cognitive Behavioral Therapy for Internet Addicts
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The study aims to explore the effect of cognitive behavioral therapy on internet addiction among university students. The experimental method was used. The study population consisted of (100) university students (50 males, 50 females). The Research sample included (13) University students at Baghdad University addicted to the Internet (9 males, 4 females), divided into two groups:  a control group consisting of (6) individuals (4 males, 2 females) and an experimental sample consisting of (6) individuals (4 males, 2 females). The Scale of Internet Addiction by Young (1996), which was translated and modified into the Arabic language by (Moegel and Prism, 2016), was administered to the study sample. The sample was subjected to two sess

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Publication Date
Mon Apr 17 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Effect of Variety, Gibberellic Acid Concentration and Spraying Duration on Steroidal Saponine Concentration of Trigonella foenum – graecum L.
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A biological experiment was conducted in the field of Biology Department-College of Education (Ibn Al-Haitham) University of Baghdad for growing season of (2004-2005), to study the effect of two varieties of the fenugreek plant (Trigonella foenum – graeccum L.) and gibberellic acid concentration (0, 25, 50, 100, 125) part per million and duration of four spraying (15, 20, 25, 30) day determining concentration medicinal active saponine compounds like (Trigonelline, choline, Carpaine and Gentianine).  The experiment was performed according to complete Randomize Complete Blocks Design (RBCD) by three replicate was adopted, means were compared by using the least significant difference at (0.05) probability level. Results showed t

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Publication Date
Wed Jan 01 2020
Journal Name
Research Journal Of Pharmacy And Technology
The effectiveness of topical vitamin k cream 1% in the treatment of steroid-induced rosacea
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Publication Date
Sun Apr 16 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Synthesis, Characterization and Antibacterial Activity of Some New Five-Seven Membered Rings Attached to Sulfonamide Compounds
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   This work includes the  synthesis of some new five- seven heterocyclic rings derived from benzenesulfonylhydrazide as starting material. Its condensation with 4-methoxy and 4nitro benzaldehyde gives the Schiff bases (1a,b). Schiff bases were reacted with cyclic anhydrides given  Oxazepine, Thiazepine derivatives(2,3,4 a,b)(seven membered ring) and with 2-mercapto benzoic acid gives thiazine derivatives (6a,b)(six membered ring) finally with thioglycolic acid give thiazolidine ring(five membered ring) scheme(3). The synthesized compounds have been characterized by melting points,FT-IR, 1H-NMR spectroscopy ,13CNMR and Elemental analysis. some of synthesized  compounds were tested for their antibacterial activity

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Publication Date
Mon Aug 26 2019
Journal Name
Iraqi Journal Of Science
Depth dose measurement in water phantom for two X-ray energies (6MeV and 10MeV) in comparison with actual planning
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The purpose of this study is to measure doses delivered at different depths in water phantom at vertical position in comparison with the actual planning in order to verify the dose delivered to the tumor in addition to the measurement of the effect penumbra dose to assess the dose leaking to the healthy soft tissue.

     Percentage depth dose (PDD) values was measured at field sizes (5×5,10×10,15×15, and 20×20) cm2, and the depth dose was measured between (0-16) cm deep at 4cm intervals, for both energies 6 MeV and 10 MeV X-ray beam. Other readings were taken at different distances 1cm and 2cm outside of the actual beam in orthogonal directions at depth of 4 cm. These measurements we

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Publication Date
Wed Nov 30 2022
Journal Name
Iraqi Journal Of Science
Measurement of Radiation Background and Estimation of the Annual Effective Dose for Workers in the Radiochemistry Laboratories at the Al-Tuwaitha Site
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      This study was achieved to calculate the annual effective dose equivalent (AEDE) in units of (mSv.y-1), and the average radiation dose rate (ADR) in units of (μSv.h-1) which were measured by portable devices.   The study was carried out on the workers of the destroyed radiochemistry laboratory located at Al-Twuitha nuclear site (south of Baghdad). Radiation background was determined for comparison with the radioactive dose of soil samples measured with HPGe detector and portable devices type LUDLUM.  The radioactivity levels of the area around the radiochemistry laboratory building were within the limits of radiation background.  The result showed a significant increase of the annua

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Publication Date
Sat Jan 20 2024
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
The Dynamic Role of PD-1, Vitamin D, RANKL, and Sclerostin in Iraqi Patients with Systemic Lupus Erythematosus
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Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease, with a wide range of clinical symptoms. Some studies have indicated the association between RANKL, Sclerostin, PD-1, and vitamin D concentrations and the pathogenesis of SLE. The current study aimed to evaluate the role of RANKL, Sclerostin, PD-1 and vitamin D in the pathogenesis of SLE. The study included 180 females diagnosed SLE patients and healthy control (60 females as early diagnosed patients without treatment, 60 females as patients under treatment with (prednisolone, and hydroxychloroquine), and 60 females healthy as a control group, with ages ranging from 20 to 45 years. The serum concentration levels of RANKL, Sclerostin, PD-1 and vitamin D were assessed by E

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Publication Date
Wed May 10 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Effect of Rhizopus Stolonifer Metabolic Products on Serum Vitamin C , some elements and catalase in albino male rats
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 The present study was designed to investigate the effect of R. stolonifer metabolic products on some antioxidant defenses and some elements (Cu, Fe, Ca) . The experiment was performed using 25 mature male rats, their age average was about (3-3.5) months and their weight average was about (200-225) gm. The animals were randomly divided into 5 equal groups (five animals for each): control (treated orally with normal saline) and four treatment groups were drenched orally with four concentrations of R. stolonifer metabolic products (15, 30, 60,120) μl/kg body weight. The animals were treated with one single dose of the previously described concentrations then left for 15 days. Animals of different groups were sacrificed under light

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Publication Date
Sun May 26 2019
Journal Name
Iraqi Journal Of Science
Determination of Vitamin B6 (pyridoxine hydrochloride) in Pharmaceutical Preparations Using High Performance Liquid Chromatography
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Determination of vitamin B6 (pyridoxine hydrochloride) was described using high performance liquid chromatographic method. The analysis was achieved by cosmos IL 5C18-MS-II column (250 mm x 4.6 mm i. d., 5µm particle size) at room temperature. The mobile phase used was Acetonitrile, buffer solution (Citric acid, Na2HPO4 pH4) buffer solution in the ratio (70:30) (V: V). the flow rate was set to 1.25 mL.min-1 and the retention time 1.82 min with UV-detection at 282 nm. Beer's law was obeyed over the concentration range 10-1250 µg.mL-1. The method was accurate (relative error % less than 0.05%), precise (RSD better than ±1.05%), average recovery 100.

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Publication Date
Wed Nov 30 2022
Journal Name
مجلة الجامعة العراقية
The competencies of lecturers and their roles in managing E-training workshops, a Pedagogical Pointview
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The aim of the research is to shed light on identifying the extent of the university professor's competencies and their roles in managing and training participants in e-training workshops as a pedagogical point view. The research sample consisted of a group of (30) university professors (lecturers) in the training workshops, in scientific,humanitarian and social disciplines, including (12) a university professor (holding a trainer certificate), , the research methodology is descriptive, and the community is a group of trained participants. (115) participated in (40) e-training workshops organized by the Center for Continuing Education at the University of Baghdad (and the selection of workshops within the researcher's specialization in the

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