Preferred Language
Articles
/
bijps-539
Dose-dependent Anti-inflammatory Effect of Silymarin in Experimental Animal Model of Acute Inflammation
...Show More Authors

Silymarin, a flavolignans from seeds of ‘milk thistle’ “Silybum marianum” has been widely used from ancient times because of its excellent hepatoprotective action. It has been used clinically to treat liver disorders including acute and chronic viral hepatitis, toxin/drug-induced hepatitis and cirrhosis and alcoholic liver disease. The efficacy and dose-response effect of silymarin (125, 250 and 500 mg/kg) were assessed using egg albumin-induced paw edema in rats as a model of acute inflammation. In this model, 56 rats were used and allocated into 7 subgroups each containing 8 rats. All treatments were given intraperitonealy 30 minutes before induction of inflammation by egg albumin and then the increase in paw edema was measured 1h, 2h and 3h after induction of inflammation by using the vernier caliper. The results indicated that silymarin, at doses range used, significantly lowered paw edema (P<0.05) an effect comparable to that produced by the reference drugs, acetyl salicylic acid, meloxicam and dexamethazone. Paw edema suppressive effect of silymarin 250 and 500 mg/kg was comparable and both of them were significantly different from that of silymarin 125 mg/kg (P<0.05). Therefore, silymarin exert an important anti-inflammatory activity in animal model of acute inflammation, which was significantly increased as the dose increased up to 250 mg/kg.

Key words: Silymarin, acute inflammation, dose-response

Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Fri Dec 02 2022
Journal Name
Periodicals Of Engineering And Natural Sciences
Histological and immunohistochemical study of thyroid gland in Caucasian squirrel (Sciurus anamalus) (Gmelin, 1778) by using marker (Anti-Thyroglobulin, Code IR5090)
...Show More Authors

The current study is designed to investigate the histological and immunohistochemical characteristics of the thyroid gland in adult male Sciurus anamalus. This study found that the thyroid gland of the Caucasian squirrel is located in the neck area, below the larynx, on both sides of the trachea. It has two lobes (right and left) with cylindrical shape. The histological studies revealed that the thyroid gland is surrounded by a capsule which consists of connective tissue and forming of two layers which are outer layer and inner layer, and a layer of adipose tissue appears overlapping the outer layer. The inner tissue of the gland consists of follicles with different shapes and sizes, and is lined with simple cuboidal epithelial tissue (foll

... Show More
Publication Date
Wed Sep 02 2020
Journal Name
International Journal Of Pharmaceutical Research
A Study of Anti-Fungal Activity for Some Antibiotics Against Aspergillus spp. and Candida spp. in Iraqi patients with Diabetes Mellitus
...Show More Authors

View Publication
Scopus Crossref
Publication Date
Fri Apr 01 2016
Journal Name
Journal Of Engineering
Experimental Behavior of Steel-Concrete-Steel Sandwich Beams with Truss Configuration of Shear Connectors
...Show More Authors

This paper presents experimentally a new configuration of shear connector for Steel-Concrete-Steel (SCS) sandwich beams that is derived from truss configuration. It consists of vertical and inclined shear connectors welded together and to cover steel plates infilled with concrete. Nine simply supported SCS beams were tested until the failure under a concentrated central load (three- point bending). The beams were similar in length (1100mm), width (100mm), and the top plate thickness (4mm). The test parameters were; beam thickness (150, 200, 250, and 300mm), the bottom plate thickness (4, and 6mm), the diameter of the shear connectors (10, 12, and 16mm), and the connector spacing (100, 200, and 250mm). The test results sh

... Show More
View Publication Preview PDF
Publication Date
Fri Jun 01 2012
Journal Name
Journal Of Engineering
Experimental and numerical evaluation of friction stirs welding of AA 2024-W aluminum alloy
...Show More Authors

Friction Stir Welding (FSW) is one of the most effective solid states joining process and has numerous potential applications in many industries. A FSW numerical tool, based on ANSYS F.E software, has been developed. The amount of the heat gone to the tool dictates the life of the tool and the capability of the tool to produce a good processed zone. Hence, understanding the heat transfer aspect of the friction stir welding is extremely important for improving the process. Many research works were carried out to simulate the friction stir welding using various softwares to determine the temperature distribution for a given set of welding conditions. The objective of this research is to develop a finite element sim

... Show More
View Publication Preview PDF
Crossref (2)
Crossref
Publication Date
Thu Dec 01 2022
Journal Name
Journal Of Engineering
An Experimental Study of Compaction and Strength of Stabilized Cohesive Soil by Stone Powder
...Show More Authors

The In this experimental study, natural stone powder was utilized to improve a cohesive soil’s compaction and strength properties. According to the significant availability of limestone in the globe, it has been chosen for the purpose of the study, in addition to considering the existing rock industry massive waste. Stone powder was used in percentages of 4, 8, 12, 16% replaced from the soil weight in dry state. Some of cohesive soil’s consistency, shear, and compaction properties were depicted after improvement. The outcomes yielded in significant amendments in the experimented geotechnical properties after stone powder addition considering 60 days curing period. Cohesion and friction angle were notably increased by

... Show More
View Publication Preview PDF
Crossref
Publication Date
Sat Jan 01 2022
Journal Name
Thermal Science
Experimental investigation of the thermal performance of wet cooling tower with splash fills packing
...Show More Authors

With the increasing intensity of the ecological and environmental problems and the scarcity of fresh water, this paper was introduced to investigate the ability to use treated wastewater as a cooling media via studying its behavior throughout a cooling tower. The simultaneous transfer of heat and mass from the treated wastewater to air over splash-fill packing arranged in a zigzag manner was studied. The characteristic of the cooling tower, the outlet water temperature, and the rejected heat were investigated as the water-to-air ratio and inlet water temperature were varied. The core results show that the cooling tower of the tower decreases with increasing water-to-air ratio, and increases with the raise of inlet water temperature.

... Show More
View Publication
Scopus (8)
Crossref (6)
Scopus Clarivate Crossref
Publication Date
Wed Nov 03 2021
Journal Name
European Journal Of Humanities And Educational Advancements (
Impact of ASSURE Model on Mathematical Correlation and Achievement in Mathematics
...Show More Authors

Publication Date
Mon Jul 01 2019
Journal Name
Iop Conference Series: Materials Science And Engineering
3D geological model of Nahr Umr/Ratawi oil field in Basra
...Show More Authors
Abstract<p>The study includes building a 3-D geological model, which involves get the Petrophysical properties as (porosity, permeability and water saturation). Effective Porosity, water saturation results from log interpretation process and permeability from special correlation using core data and log data. Clay volume can be calculated by six ways using IP software v3.5 the best way was by using gamma Ray. Also, Water Resistivity, flushed zone saturation and bulk volume analysis determined through geological study. Lithology determined in several ways using M-N matrix Identification, Density-Neutron and Sonic-Neutron cross plots. The cut off values are determined by Using EHC (Equivalent Hydra</p> ... Show More
View Publication
Scopus Crossref
Publication Date
Sun Jan 01 2023
Journal Name
International Conference Of Computational Methods In Sciences And Engineering Iccmse 2021
Penetration of charged particles in ZnO using energy loss function model
...Show More Authors

In this paper, we propose an approach to estimate the induced potential, which is generated by swift heavy ions traversing a ZnO thin film, via an energy loss function (ELF). This induced potential is related to the projectile charge density, ρq(k) and is described by the extended Drude dielectric function. At zero momentum transfer, the resulting ELF exhibits good agreement with the previously reported results. The ELF, obtained by the extended Drude model, displays a realistic behavior over the Bethe ridge. It is observed that the induced potential relies on the heavy ion velocity and charge state q. Further, the numerical results show that the induced potential for neutral H, as projectile, dominates when the heavy ion velocity is less

... Show More
View Publication
Scopus Crossref
Publication Date
Sat Dec 30 2023
Journal Name
Iraqi Journal Of Science
Design of Optimal Control for the In-host Tuberculosis Fractional Model
...Show More Authors

     In this article, we investigate a mathematical fractional model of tuberculosis that takes into account vaccination as a possible way to treat the disease. We use an in-host tuberculosis fractional model that shows how Macrophages and Mycobacterium tuberculosis interact to knowledge of how vaccination treatments affect macrophages that have not been infected. The existence of optimal control is proven. The Hamiltonian function and the maximum principle of the Pontryagin are used to describe the optimal control. In addition, we use the theory of optimal control to develop an algorithm that leads to choosing the best vaccination plan. The best numerical solutions have been discovered using the forward and backward fractional Euler

... Show More
View Publication Preview PDF
Scopus (1)
Scopus Crossref